(Q35723875)

English

Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair

scientific article published on 12 January 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

0 references

1 reference

ChEBI release 2020-05-28

1 reference

ChEBI release 2020-05-28

author name string

A D Bulgar

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

L D Weeks

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Y Miao

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

S Yang

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Y Xu

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

C Guo

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

S Markowitz

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

N Oleinick

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

S L Gerson

9

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

L Liu

10

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

12 January 2012

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Europe PubMed Central

PubMed publication ID

9 August 2017

Cell Death and Disease

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Europe PubMed Central

PubMed publication ID

9 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

e252

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3270269/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3270269/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1038/cddis.2011.135

0 references

Synthetic lethality: exploiting the addiction of cancer to DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Uracil DNA N-glycosylase promotes assembly of human centromere protein A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

DNA topoisomerase II and its growing repertoire of biological functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation

1 reference

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Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins

1 reference

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12 July 2018

Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide.

1 reference

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Reverse engineering of regulatory networks in human B cells

1 reference

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12 July 2018

Characterization of an archaeal family 4 uracil DNA glycosylase and its interaction with PCNA and chromatin proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells

1 reference

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12 July 2018

Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation

1 reference

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A serine protease is involved in the initiation of DNA damage-induced apoptosis

1 reference

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12 July 2018

Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Molecular, biochemical, and cellular pharmacology of pemetrexed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Uracil in DNA--occurrence, consequences and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

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Diversity of gene expression in adenocarcinoma of the lung

1 reference

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Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

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12 July 2018

Topoisomerase II can unlink replicating DNA by precatenane removal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Genome maintenance mechanisms for preventing cancer

1 reference

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12 July 2018

Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents

1 reference

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12 July 2018

Post-replicative base excision repair in replication foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues

1 reference

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IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

DNA glycosylases in the base excision repair of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270269

12 July 2018

Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG gene

1 reference

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12 July 2018

Relationship between 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas

1 reference

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12 July 2018

Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme

1 reference

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12 July 2018

Processing in vitro of an abasic site reacted with methoxyamine: a new assay for the detection of abasic sites formed in vivo.

1 reference

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Targeting base excision repair suggests a new therapeutic strategy of fludarabine for the treatment of chronic lymphocytic leukemia

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25 September 2018

Blockage of abasic site repair enhances antitumor efficacy of 1,3-bis-(2-chloroethyl)-1-nitrosourea in colon tumor xenografts

1 reference

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25 September 2018

Base excision repair as a therapeutic target in colon cancer.

1 reference

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25 September 2018

Apurinic sites are position-specific topoisomerase II poisons.

1 reference

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25 September 2018

A specific partner for abasic damage in DNA

1 reference

https://api.crossref.org/works/10.1038%2FCDDIS.2011.135

21 January 2018

A new approach to the study of the base-excision repair pathway using methoxyamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22237209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The type of DNA glycosylase determines the base excision repair pathway in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22237209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection against methylation-induced cytotoxicity by DNA polymerase beta-dependent long patch base excision repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/22237209

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CDDIS.2011.135

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dimensions Publication ID

0 references

release_mosfm2hvzffzjn2kyl4ensooyq

1 reference

https://api.fatcat.wiki/v0/release/mosfm2hvzffzjn2kyl4ensooyq

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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