(Q35724871)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

review article

1 reference

title

Systematic review: bile acids and intestinal inflammation-luminal aggressors or regulators of mucosal defence? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

1

1 reference

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20 February 2020

Nick Powell

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

author name string

R P Vincent

3

1 reference

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20 February 2020

D Ehrlich

4

1 reference

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20 February 2020

I Bjarnason

5

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20 February 2020

B Hayee

6

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20 February 2020

language of work or name

English

0 references

publication date

29 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

Alimentary Pharmacology & Therapeutics

20 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

volume

42

1 reference

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20 February 2020

issue

7

1 reference

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20 February 2020

page(s)

802-817

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades

20 February 2020

cites work

1 reference

Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity

21 January 2018

1 reference

Role of CAR and PXR in xenobiotic sensing and metabolism

21 January 2018

1 reference

Identification of a nuclear receptor for bile acids

21 January 2018

1 reference

Bile acids: natural ligands for an orphan nuclear receptor

21 January 2018

1 reference

21 January 2018

Physiology of FGF15/19

1 reference

Bile salt biotransformations by human intestinal bacteria

21 January 2018

1 reference

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

21 January 2018

1 reference

Bile acids: trying to understand their chemistry and biology with the hope of helping patients

21 January 2018

1 reference

Bile acids and the gut microbiome

21 January 2018

1 reference

A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis

21 January 2018

1 reference

Bile salt malabsorption in regional ileitis, ileal resection and mannitol-induced diarrhea

21 January 2018

1 reference

Bile acid studies in uncomplicated Crohn's disease

21 January 2018

1 reference

Bile acid absorption kinetics in Crohn's disease on elemental diet after oral administration of a stable-isotope tracer with chenodeoxycholic-11, 12-d2 acid

21 January 2018

1 reference

Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT

21 January 2018

1 reference

Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation

21 January 2018

1 reference

c-Fos is a critical mediator of inflammatory-mediated repression of the apical sodium-dependent bile acid transporter.

21 January 2018

1 reference

Bile acid studies in patients with Crohn's colitis

21 January 2018

1 reference

Effects of ileal resection on biliary lipids and bile acid composition in patients with Crohn's disease

21 January 2018

1 reference

Bile composition in inflammatory bowel disease: ileal disease and colectomy, but not colitis, induce lithogenic bile

21 January 2018

1 reference

Kinetics of primary bile acids in patients with non-operated Crohn's disease.

21 January 2018

1 reference

Shotgun cholanomics of ileal fluid

21 January 2018

1 reference

Ileal dysfunction in Crohn's disease assessed by the postprandial serum bile acid response

21 January 2018

1 reference

Postprandial serum bile acids in resected and non-resected patients with Crohn's disease.

21 January 2018

1 reference

Fasting and postprandial serum concentrations of glycine- and taurine-conjugated bile acids in Crohn's disease.

21 January 2018

1 reference

Medical management of patients with ileal pouch anal anastomosis after restorative procto-colectomy

21 January 2018

1 reference

Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel disease

21 January 2018

1 reference

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases.

21 January 2018

1 reference

Surface area of the digestive tract - revisited

21 January 2018

1 reference

21 January 2018

1 reference

Intestinal permeability defects: is it time to treat?

21 January 2018

1 reference

Healthy controls have as much bile reflux as gastric ulcer patients

21 January 2018

1 reference

Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics

21 January 2018

1 reference

Bile salt damage of egg phosphatidylcholine liposomes.

21 January 2018

1 reference

Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells

21 January 2018

1 reference

Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation.

21 January 2018

1 reference

Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions.

21 January 2018

1 reference

Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis

21 January 2018

1 reference

Bile acid hydrophobicity is correlated with induction of apoptosis and/or growth arrest in HCT116 cells

21 January 2018

1 reference

Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids

21 January 2018

1 reference

Modulation of the fecal bile acid profile by gut microbiota in cirrhosis

21 January 2018

1 reference

Colonic inflammation and secondary bile acids in alcoholic cirrhosis

21 January 2018

1 reference

Characterization of bacteria in biopsies of colon and stools by high throughput sequencing of the V2 region of bacterial 16S rRNA gene in human

21 January 2018

1 reference

The treatment-naive microbiome in new-onset Crohn's disease

21 January 2018

1 reference

Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases

21 January 2018

1 reference

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

21 January 2018

1 reference

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota

21 January 2018

1 reference

Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's disease mucosa.

21 January 2018

1 reference

High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn’s disease

21 January 2018

1 reference

Adherent invasive Escherichia coli strains from patients with Crohn's disease survive and replicate within macrophages without inducing host cell death

21 January 2018

1 reference

Adherent-invasive Escherichia coli isolated from Crohn's disease patients induce granulomas in vitro

21 January 2018

1 reference

Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response

21 January 2018

1 reference

Pathogenesis of aphthoid ulcers in Crohn's disease: correlative findings by magnifying colonoscopy, electron microscopy, and immunohistochemistry

21 January 2018

1 reference

Crohn disease--associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae

21 January 2018

1 reference

Colonic mucosa-associated diffusely adherent afaC+ Escherichia coli expressing lpfA and pks are increased in inflammatory bowel disease and colon cancer.

21 January 2018

1 reference

Bile salts induce long polar fimbriae expression favouring Crohn's disease-associated adherent-invasive Escherichia coli interaction with Peyer's patches.

21 January 2018

1 reference

Dihydroxy bile acids increase mucosal permeability and bacterial uptake in human colon biopsies.

21 January 2018

1 reference

Intestinal permeability, non-steroidal anti-inflammatory drug enteropathy and inflammatory bowel disease: an overview

21 January 2018

1 reference

Mitochondrial damage: a possible mechanism of the "topical" phase of NSAID induced injury to the rat intestine

21 January 2018

1 reference

COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice

21 January 2018

1 reference

Review: The Biochemical Basis of Non-Steroidal Anti-Inflammatory Drug-Induced Damage to the Gastrointestinal Tract: A Review and a Hypothesis

21 January 2018

1 reference

Enterohepatic circulation of indomethacin and its role in intestinal irritation

21 January 2018

1 reference

Indomethacin-induced intestinal lesions in the rat

21 January 2018

1 reference

NSAIDs: take with food or after fasting?

21 January 2018

1 reference

Effect of indomethacin on bile acid-phospholipid interactions: implication for small intestinal injury induced by nonsteroidal anti-inflammatory drugs

21 January 2018

1 reference

Ursodeoxycholic acid ameliorates experimental ileitis counteracting intestinal barrier dysfunction and oxidative stress.

21 January 2018

1 reference

Role of intestinal bacteria in ileal ulcer formation in rats treated with a nonsteroidal antiinflammatory drug.

21 January 2018

1 reference

Metronidazole reduces intestinal inflammation and blood loss in non-steroidal anti-inflammatory drug induced enteropathy

21 January 2018

1 reference

Binding of Clostridium difficile cytotoxin and vancomycin by anion-exchange resins

21 January 2018

1 reference

Endotoxaemia and renal failure in cirrhosis and obstructive jaundice

21 January 2018

1 reference

Physical aspects of reversible inactivation of endotoxin

21 January 2018

1 reference

Prevention of endotoxaemia in obstructive jaundice--a comparative study of bile salts

21 January 2018

1 reference

Regulation of antibacterial defense in the small intestine by the nuclear bile acid receptor

21 January 2018

1 reference

Bile salts and glycine as cogerminants for Clostridium difficile spores

21 January 2018

1 reference

Clostridium difficile infection: new developments in epidemiology and pathogenesis

21 January 2018

1 reference

Chenodeoxycholate is an inhibitor of Clostridium difficile spore germination

21 January 2018

1 reference

Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile.

21 January 2018

1 reference

Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa B-induced expression of transforming growth factor-beta

21 January 2018

1 reference

Bile salts affect epithelial restitution

21 January 2018

1 reference

Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression

21 January 2018

1 reference

Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice

21 January 2018

1 reference

Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs

21 January 2018

1 reference

Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice

21 January 2018

1 reference

The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis

21 January 2018

1 reference

Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier

21 January 2018

1 reference

Vitamin D receptor as an intestinal bile acid sensor

21 January 2018

1 reference

Failure of T cell homing, reduced CD4/CD8alphaalpha intraepithelial lymphocytes, and inflammation in the gut of vitamin D receptor KO mice

21 January 2018

1 reference

Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis

21 January 2018

1 reference

The bile acid receptor FXR is a modulator of intestinal innate immunity

21 January 2018

1 reference

The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation

21 January 2018

1 reference

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells

21 January 2018

1 reference

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

21 January 2018

1 reference

Pregnane X receptor agonists enhance intestinal epithelial wound healing and repair of the intestinal barrier following the induction of experimental colitis

21 January 2018

1 reference

Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system.

21 January 2018

1 reference

TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading

21 January 2018

1 reference

The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice

21 January 2018

1 reference

TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease

21 January 2018

1 reference

Exploring the full spectrum of macrophage activation

21 January 2018

1 reference

Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages

21 January 2018

1 reference

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine.

21 January 2018

1 reference

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease

21 January 2018

1 reference

Pharmacological activation of the bile acid nuclear farnesoid X receptor is feasible in patients with quiescent Crohn's colitis.

21 January 2018

1 reference

PPARα-UGT axis activation represses intestinal FXR-FGF15 feedback signalling and exacerbates experimental colitis.

21 January 2018

1 reference

The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid.

21 January 2018

1 reference

Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.

21 January 2018

1 reference

Association of genetic variation in the NR1H4 gene, encoding the nuclear bile acid receptor FXR, with inflammatory bowel disease

21 January 2018

1 reference

Associations between vitamin D receptor polymorphisms and susceptibility to ulcerative colitis and Crohn's disease: a meta-analysis

21 January 2018

1 reference

Metabolomics reveals metabolic biomarkers of Crohn's disease

21 January 2018

1 reference

Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease

21 January 2018

1 reference

Bowel inflammation as measured by fecal calprotectin: a link between lifestyle factors and colorectal cancer risk.

21 January 2018

1 reference

Intestinal permeability parameters in obese patients are correlated with metabolic syndrome risk factors.

21 January 2018

1 reference

Circulating zonulin, a marker of intestinal permeability, is increased in association with obesity-associated insulin resistance

21 January 2018

1 reference

Chronic subclinical bowel inflammation may explain increased risk of colorectal cancer in obese people.

21 January 2018

1 reference

Faecal calprotectin levels before and after weight loss in obese and overweight subjects

21 January 2018

1 reference

Relationship between severe obesity and gut inflammation in children: what's next?

21 January 2018

1 reference

Weight loss induced by Roux-en-Y gastric bypass but not laparoscopic adjustable gastric banding increases circulating bile acids.

21 January 2018

1 reference

Enhanced fasting and post-prandial plasma bile acid responses after Roux-en-Y gastric bypass surgery.

21 January 2018

1 reference

FXR is a molecular target for the effects of vertical sleeve gastrectomy

21 January 2018

1 reference

Measures of obesity and risk of Crohn's disease and ulcerative colitis

21 January 2018

1 reference

Review article: evidence-based dietary advice for patients with inflammatory bowel disease

21 January 2018

1 reference

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

21 January 2018

1 reference

Western diet induces dysbiosis with increased E coli in CEABAC10 mice, alters host barrier function favouring AIEC colonisation

21 January 2018

1 reference

The impact of inflammatory bowel disease post-liver transplantation for primary sclerosing cholangitis

21 January 2018

1 reference

PSC, AIH and overlap syndrome in inflammatory bowel disease

21 January 2018

1 reference

The role of bile salts in diarrhoea of patients with ulcerative colitis

21 January 2018

1 reference

Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor

21 January 2018

1 reference

A simple and accurate HPLC method for fecal bile acid profile in healthy and cirrhotic subjects: validation by GC-MS and LC-MS.

21 January 2018

1 reference

Postprandial plasma bile acid responses in normal weight and obese subjects

21 January 2018

1 reference

Bile acid receptors as targets for drug development.

21 January 2018

1 reference

Pregnane X receptor as a target for treatment of inflammatory bowel disorders

21 January 2018

1 reference

The bile acid TGR5 membrane receptor: from basic research to clinical application

21 January 2018

1 reference

Vitamin D, immune regulation, the microbiota, and inflammatory bowel disease

21 January 2018

1 reference

Biochemical epidemiology of gallbladder cancer

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/APT.13333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26223936%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference