(Q54354711)

28 May 2018

title

Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. (English)

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inflammatory bowel diseases

main subject

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author name string

Jürgen Glas

1

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Julia Seiderer

2

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Daniel Fischer

3

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Barbara Tengler

4

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Simone Pfennig

5

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Martin Wetzke

6

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Florian Beigel

7

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Torsten Olszak

8

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Maria Weidinger

9

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Burkhard Göke

10

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Thomas Ochsenkühn

11

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Matthias Folwaczny

12

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Bertram Müller-Myhsok

13

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Julia Diegelmann

14

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Darina Czamara

15

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Stephan Brand

16

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publication date

3 December 2010

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Inflammatory Bowel Diseases

published in

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volume

17

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issue

9

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28 May 2018

page(s)

1917-1924

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28 May 2018

Review article: Inflammatory bowel disease and genetics

cites work

1 reference

Unravelling the pathogenesis of inflammatory bowel disease

21 January 2018

1 reference

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease

21 January 2018

1 reference

Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal stenoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study.

21 January 2018

1 reference

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants

21 January 2018

1 reference

Loss of detoxification in inflammatory bowel disease: dysregulation of pregnane X receptor target genes.

21 January 2018

1 reference

Pregnane X receptor: promiscuous regulator of detoxification pathways

21 January 2018

1 reference

PXR: a xenobiotic receptor of diverse function implicated in pharmacogenetics

21 January 2018

1 reference

PXR and CAR in energy metabolism

21 January 2018

1 reference

Evaluation of 170 xenobiotics as transactivators of human pregnane X receptor (hPXR) and correlation to known CYP3A4 drug interactions

21 January 2018

1 reference

The antiapoptotic role of pregnane X receptor in human colon cancer cells

21 January 2018

1 reference

PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonide

21 January 2018

1 reference

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

21 January 2018

1 reference

The effects of splicing variant of PXR PAR-2 on CYP3A4 and MDR1 mRNA expressions

21 January 2018

1 reference

Lack of association of the pregnane X receptor (PXR/NR1I2) gene with inflammatory bowel disease: parallel allelic association study and gene wide haplotype analysis.

21 January 2018

1 reference

Investigation of associations between the pregnane-X receptor gene (NR1I2) and Crohn's disease in Canadian children using a gene-wide haplotype-based approach

21 January 2018

1 reference

Nuclear pregnane X receptor single nucleotide polymorphism (-25385C/T) is not associated with inflammatory bowel disease in pediatric patients.

21 January 2018

1 reference

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

Effects of budesonide on P-glycoprotein expression in intestinal cell lines

21 January 2018

1 reference

Rifaximin is a gut-specific human pregnane X receptor activator

21 January 2018

1 reference

Rifaximin for the treatment of newly diagnosed Crohn's disease: a case series

21 January 2018

1 reference

An open-label evaluation of rifaximin in the treatment of active Crohn's disease

21 January 2018

1 reference

The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases.

21 January 2018

1 reference

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IBD.21562

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28 May 2018

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28 May 2018