(Q35728813)

English

Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons

scientific article published on 13 December 2011

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons (English)

1 reference

Europe PubMed Central

9 August 2017

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Eliezer Masliah

4

object named as

Eliezer Masliah

1 reference

Europe PubMed Central

9 August 2017

Marie-Françoise Chesselet

5

object named as

Marie-Francoise Chesselet

1 reference

Europe PubMed Central

9 August 2017

author name string

Yofre Cabeza-Arvelaiz

1

1 reference

Europe PubMed Central

9 August 2017

Sheila M Fleming

2

1 reference

Europe PubMed Central

9 August 2017

Franziska Richter

3

1 reference

Europe PubMed Central

9 August 2017

Robert H Schiestl

6

1 reference

Europe PubMed Central

9 August 2017

publication date

13 December 2011

1 reference

Europe PubMed Central

9 August 2017

Molecular Neurodegeneration

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Europe PubMed Central

9 August 2017

6

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Europe PubMed Central

9 August 2017

83

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Europe PubMed Central

9 August 2017

https://scigraph.springernature.com/pub.10.1186/1750-1326-6-83

0 references

Elevated tonic extracellular dopamine concentration and altered dopamine modulation of synaptic activity precede dopamine loss in the striatum of mice overexpressing human α-synuclein

1 reference

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Genetic mouse models of Parkinson's disease The state of the art.

1 reference

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1 reference

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The regulation of synaptic function by alpha-synuclein

1 reference

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1 reference

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A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration.

1 reference

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1 reference

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Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein

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Olfactory deficits in mice overexpressing human wildtype alpha-synuclein

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Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein

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1 reference

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Clinical correlates of similar pathologies in parkinsonian syndromes

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Intracellular cholesterol transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/22165993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotine enhances the biosynthesis and secretion of transthyretin from the choroid plexus in rats: implications for beta-amyloid formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22165993

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based on heuristic

inferred from PubMed ID database lookup

Human Wild-Type α-Synuclein Impairs Neurogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22165993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1750-1326-6-83

1 reference

Europe PubMed Central

9 August 2017

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1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

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