(Q35733292)

10 August 2017

title

Testin and actin are key molecular targets of adjudin, an anti-spermatogenic agent, in the testis (English)

1 reference

10 August 2017

1

Dolores D Mruk

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10 August 2017

C Yan Cheng

2

1 reference

10 August 2017

publication date

1 April 2011

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10 August 2017

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10 August 2017

volume

1

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10 August 2017

issue

2

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10 August 2017

page(s)

137-146

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Spermiation: The process of sperm release

10 August 2017

cites work

1 reference

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Spermatogonial stem cells alone are not sufficient to re-initiate spermatogenesis in the rat testis following adjudin-induced infertility.

12 July 2018

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Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

The biology of the desmosome-like junction a versatile anchoring junction and signal transducer in the seminiferous epithelium

12 July 2018

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New mechanisms and functions of actin nucleation

12 July 2018

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New frontiers in nonhormonal male contraception

12 July 2018

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WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond

12 July 2018

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Hormonal approaches to male contraception

12 July 2018

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Cell adhesion: integrating cytoskeletal dynamics and cellular tension

12 July 2018

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A local autocrine axis in the testes that regulates spermatogenesis

12 July 2018

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The biology of spermatogenesis: the past, present and future

12 July 2018

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An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

RAB13 participates in ectoplasmic specialization dynamics in the rat testis

12 July 2018

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Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis

12 July 2018

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Anchoring junctions as drug targets: role in contraceptive development

12 July 2018

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New perspectives in non-hormonal male contraception

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

A novel potent indazole carboxylic acid derivative blocks spermatogenesis and is contraceptive in rats after a single oral dose

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Gamendazole, an orally active indazole carboxylic acid male contraceptive agent, targets HSP90AB1 (HSP90BETA) and EEF1A1 (eEF1A), and stimulates Il1a transcription in rat Sertoli cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Junction restructuring and spermatogenesis: the biology, regulation, and implication in male contraceptive development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Mechanism of depolymerization and severing of actin filaments and its significance in cytoskeletal dynamics.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Unraveling the molecular targets pertinent to junction restructuring events during spermatogenesis using the Adjudin-induced germ cell depletion model

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Ectoplasmic specialization: a friend or a foe of spermatogenesis?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

A male contraceptive targeting germ cell adhesion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Adjudin-mediated junction restructuring in the seminiferous epithelium leads to displacement of soluble guanylate cyclase from adherens junctions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

AF-2364 [1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide] is a potential male contraceptive: a review of recent data

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Strength measurement of the Sertoli-spermatid junctional complex.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Eps8 controls actin-based motility by capping the barbed ends of actin filaments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Cell-cell interactions at the ectoplasmic specialization in the testis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Dynamic cross-talk between cells and the extracellular matrix in the testis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Zyxin, axin, and Wiskott-Aldrich syndrome protein are adaptors that link the cadherin/catenin protein complex to the cytoskeleton at adherens junctions in the seminiferous epithelium of the rat testis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Fer Kinase/FerT and Adherens Junction Dynamics in the Testis: An In Vitro and In Vivo Study1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Ectoplasmic specializations in the Sertoli cell: new vistas based on genetic defects and testicular toxicology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Rab8B GTPase and junction dynamics in the testis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Regulation of Sertoli cell myotubularin (rMTM) expression by germ cells in vitro.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Testin induction: the role of cyclic 3',5'-adenosine monophosphate/protein kinase A signaling in the regulation of basal and lonidamine-induced testin expression by rat sertoli cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Unique and multifunctional adhesion junctions in the testis: ectoplasmic specializations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Testin secreted by Sertoli cells is associated with the cell surface, and its expression correlates with the disruption of Sertoli-germ cell junctions but not the inter-Sertoli tight junction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Testin is tightly associated with testicular cell membrane upon its secretion by sertoli cells whose steady-state mRNA level in the testis correlates with the turnover and integrity of inter-testicular cell junctions.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Cyclic and postnatal developmental changes of testin in the rat seminiferous epithelium--an immunohistochemical study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Rat testin is a newly identified component of the junctional complexes in various tissues whose mRNA is predominantly expressed in the testis and ovary

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Proliferation of Sertoli cells in fetal and postnatal rats: a quantitative autoradiographic study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Effects of Lonidamine on pituitary-gonadal axis in man.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Lonidamine and related compounds.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Testins are structurally related Sertoli cell proteins whose secretion is tightly coupled to the presence of germ cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271656

Two new male contraceptives exert their effects by depleting germ cells prematurely from the testis

12 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FSPMG.1.2.16449

Role of tissue inhibitor of metalloproteases-1 in junction dynamics in the testis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FSPMG.1.2.16449

Transforming growth factor beta3 regulates the dynamics of Sertoli cell tight junctions via the p38 mitogen-activated protein kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FSPMG.1.2.16449

Identification of Hormonally Responsive Proteins in Primary Sertoli Cell Culture Medium by Anion-Exchange High Performance Liquid Chromatography*

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FSPMG.1.2.16449

There goes the neighbourhood: Eps8 joins the barbed-end crowd

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FSPMG.1.2.16449

Structural analysis of clusterin and its subunits in ram rete testis fluid

21 January 2018

1 reference

12 December 2020

Male hormonal contraception

1 reference

12 December 2020

Identification of two testosterone-responsive testicular proteins in Sertoli cell-enriched culture medium whose secretion is suppressed by cells of the intact seminiferous tubule

1 reference

12 December 2020

Testins are localized to the junctional complexes of rat Sertoli and epididymal cells

1 reference

12 December 2020

Ability of trypsin in mimicking germ cell factors that affect Sertoli cell secretory function

1 reference

12 December 2020

The Sertoli-spermatid junctional complex adhesion strength is affected in vitro by adjudin

1 reference

12 December 2020

Phase II evaluation of Lonidamine in patients with advanced malignancy

1 reference

12 December 2020

A difference in the immunoglobulin content of seminiferous tubule fluid and rete testis fluid of the rat

1 reference

12 December 2020

Identifiers

DOI

10.4161/SPMG.1.2.16449

1 reference

10 August 2017

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10 August 2017

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