(Q35739939)

10 August 2017

Drosophila Longevity Assurance Conferred by Reduced Insulin Receptor Substrate Chico Partially Requires d4eBP. (English)

1 reference

10 August 2017

0 references

Marc Tatar

4

0 references

author name string

Hua Bai

series ordinal

1

1 reference

10 August 2017

Stephanie Post

series ordinal

2

1 reference

10 August 2017

Ping Kang

series ordinal

3

1 reference

10 August 2017

language of work or name

English

0 references

publication date

7 August 2015

1 reference

10 August 2017

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10 August 2017

10

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10 August 2017

8

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10 August 2017

e0134415

1 reference

Creative Commons Attribution 4.0 International

10 August 2017

start time

7 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4529185/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity

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mRNP granules. Assembly, function, and connections with disease

27 July 2018

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4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation

27 July 2018

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Rapamycin increases mitochondrial efficiency by mtDNA-dependent reprogramming of mitochondrial metabolism in Drosophila

27 July 2018

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Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila

27 July 2018

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Functional implications of Drosophila insulin-like peptides in metabolism, aging, and dietary restriction

27 July 2018

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Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan

27 July 2018

1 reference

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Role of TOR signaling in aging and related biological processes in Drosophila melanogaster

27 July 2018

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FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging

27 July 2018

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Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling

27 July 2018

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Aging, frailty and age-related diseases

27 July 2018

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Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster

27 July 2018

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Molecular mechanisms of metabolic regulation by insulin in Drosophila

27 July 2018

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4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

27 July 2018

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The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway

27 July 2018

1 reference

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d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila

27 July 2018

1 reference

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Can we develop genetically tractable models to assess healthspan (rather than life span) in animal models?

27 July 2018

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Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs

27 July 2018

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How flies get their size: genetics meets physiology

27 July 2018

1 reference

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4E-BP functions as a metabolic brake used under stress conditions but not during normal growth

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP.

27 July 2018

1 reference

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Tsc2 is not a critical target of Akt during normal Drosophila development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Localisation and regulation of the eIF4E-binding protein 4E-BP3.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Akt regulates growth by directly phosphorylating Tsc2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Genetic analysis of insulin signaling in Drosophila

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Drosophila Thor participates in host immune defense and connects a translational regulator with innate immunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Characterization of Drosophila insulin receptor substrate

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Identification of immune system and response genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Alternatively spliced transcripts from the Drosophila eIF4E gene produce two different Cap-binding proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

A C. elegans mutant that lives twice as long as wild type

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Drosophila insulin receptor: lectin-binding properties and a role for oxidation-reduction of receptor thiols in activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Insulin and Target of rapamycin signaling orchestrate the development of ovarian niche-stem cell units in Drosophila.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Tissue-specific coupling between insulin/IGF and TORC1 signaling via PRAS40 in Drosophila

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

dFOXO-independent effects of reduced insulin-like signaling in Drosophila

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

SH2B regulation of growth, metabolism, and longevity in both insects and mammals

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Effect of rapamycin on lifespan in Drosophila

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Akt phosphorylates both Tsc1 and Tsc2 in Drosophila, but neither phosphorylation is required for normal animal growth

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Identification of direct DAF-16 targets controlling longevity, metabolism and diapause by chromatin immunoprecipitation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Upstream and downstream of mTOR

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

The demography of slow aging in male and female Drosophila mutant for the insulin-receptor substrate homologue chico.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

The translational inhibitor 4E-BP is an effector of PI(3)K/Akt signalling and cell growth in Drosophila

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Genetic and biochemical characterization of dTOR, the Drosophila homolog of the target of rapamycin

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4529185

Lessons from C. elegans: signaling pathways for longevity

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26252766

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0134415

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference