(Q35742549)

English

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel

scientific article published on March 2015

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scholarly article

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Europe PubMed Central

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3 March 2020

Brassinin inhibits STAT3 signaling pathway through modulation of PIAS-3 and SOCS-3 expression and sensitizes human lung cancer xenograft in nude mice to paclitaxel (English)

1 reference

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3 March 2020

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based on heuristic

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3

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3 March 2020

author name string

Jong Hyun Lee

1

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3 March 2020

Chulwon Kim

2

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3 March 2020

Kwang Seok Ahn

4

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3 March 2020

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1 March 2015

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3 March 2020

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3 March 2020

6

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3 March 2020

8

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3 March 2020

6386-6405

1 reference

Europe PubMed Central

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3 March 2020

Targeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitor

1 reference

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Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells

1 reference

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A meta-analysis of STAT3 and phospho-STAT3 expression and survival of patients with non-small-cell lung cancer

1 reference

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The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation

1 reference

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27 July 2018

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.

1 reference

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Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.

1 reference

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27 July 2018

Brassinin induces apoptosis in PC-3 human prostate cancer cells through the suppression of PI3K/Akt/mTOR/S6K1 signaling cascades.

1 reference

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27 July 2018

STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (review).

1 reference

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27 July 2018

STAT3 is activated by JAK2 independent of key oncogenic driver mutations in non-small cell lung carcinoma.

1 reference

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27 July 2018

Brassinin induces G1 phase arrest through increase of p21 and p27 by inhibition of the phosphatidylinositol 3-kinase signaling pathway in human colon cancer cells

1 reference

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27 July 2018

Correlation of activated STAT3 expression with clinicopathologic features in lung adenocarcinoma and squamous cell carcinoma

1 reference

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Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

1 reference

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27 July 2018

Cooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer.

1 reference

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27 July 2018

Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling

1 reference

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27 July 2018

Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression

1 reference

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27 July 2018

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

1 reference

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27 July 2018

Targeting signal-transducer-and-activator-of-transcription-3 for prevention and therapy of cancer: modern target but ancient solution

1 reference

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27 July 2018

Expression of SOCS1 and SOCS3 genes is differentially regulated in breast cancer cells in response to proinflammatory cytokine and growth factor signals.

1 reference

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27 July 2018

Isobrassinin and its analogues: novel types of antiproliferative agents

1 reference

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27 July 2018

Stats: multifaceted regulators of transcription

1 reference

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27 July 2018

Controlling cytokine signaling by constitutive inhibitors

1 reference

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27 July 2018

Paclitaxel for non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4467444

27 July 2018

Differential PIAS3 expression in human malignancy

1 reference

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27 July 2018

The STATs of cancer--new molecular targets come of age

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Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells

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27 July 2018

Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers.

1 reference

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Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor

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27 July 2018

Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells

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27 July 2018

SOCS proteins: negative regulators of cytokine signaling

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Detection of functional PTEN lipid phosphatase protein and enzyme activity in squamous cell carcinomas of the head and neck, despite loss of heterozygosity at this locus

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STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

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STATs in oncogenesis

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Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR

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Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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Structure and function of a new STAT-induced STAT inhibitor

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1 reference

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A family of cytokine-inducible inhibitors of signalling

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Structure-activity relationships of brassinin in preventing the development of carcinogen-induced mammary lesions in organ culture.

1 reference

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1 reference

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27 July 2018

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1 reference

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Identifiers

10.18632/ONCOTARGET.3443

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Europe PubMed Central

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3 March 2020

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24 November 2022

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Europe PubMed Central

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3 March 2020

1 reference

Europe PubMed Central

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3 March 2020

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