(Q40633129)

22 September 2017

Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells (English)

1 reference

22 September 2017

Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells (English)

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

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1 reference

1 reference

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

author name string

Nicholas Donato

2

1 reference

22 September 2017

Alok C. Bharti

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500688

12 March 2024

Bharat B. Aggarwal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14500688

12 March 2024

language of work or name

English

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publication date

1 October 2003

1 reference

full work available at URL

22 September 2017

9

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based on heuristic

inferred from page(s)

published in

Journal of Immunology

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22 September 2017

171

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22 September 2017

3863-3871

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22 September 2017

7

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Diagnosis and management of multiple myeloma

22 September 2017

2

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

12 March 2024

5

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

STATs and gene regulation

12 March 2024

7

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Gp130 and the interleukin-6 family of cytokines

12 March 2024

8

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Stat3 activation is required for cellular transformation by v-src

12 March 2024

9

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

12 March 2024

10

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https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

12 March 2024

14

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

12 March 2024

15

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Regulation of Bcl-xL: a little bit of this and a little bit of STAT.

12 March 2024

17

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

12 March 2024

20

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Curcumin causes the growth arrest and apoptosis of B cell lymphoma by downregulation of egr-1, c-myc, bcl-XL, NF-kappa B, and p53.

12 March 2024

21

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation

12 March 2024

22

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes.

12 March 2024

23

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

12 March 2024

24

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Characteristics of established myeloma and lymphoblastoid cell lines derived from an E myeloma patient: a comparative study.

12 March 2024

25

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Overexpression of manganese superoxide dismutase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappaB and activated protein-1

12 March 2024

28

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

12 March 2024

29

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

12 March 2024

30

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

TNF and IL-6 are potent growth factors for OH-2, a novel human myeloma cell line.

12 March 2024

32

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Autocrine growth by two cytokines, interleukin-6 and tumor necrosis factor alpha, in the myeloma cell line KHM-1A.

12 March 2024

33

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Spontaneous secretion of tumor necrosis factor-beta by human myeloma cell lines

12 March 2024

34

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Production of lymphotoxin, a bone-resorbing cytokine, by cultured human myeloma cells

12 March 2024

35

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

12 March 2024

39

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Oncostatin M-induced matrix metalloproteinase and tissue inhibitor of metalloproteinase-3 genes expression in chondrocytes requires Janus kinase/STAT signaling pathway

12 March 2024

40

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells

12 March 2024

41

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain

12 March 2024

42

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner

12 March 2024

43

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

12 March 2024

44

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

12 March 2024

45

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity

12 March 2024

46

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Mechanism of STAT3 activation by insulin-like growth factor I receptor

12 March 2024

47

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity

12 March 2024

48

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner

12 March 2024

49

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Activated G protein-coupled receptor induces tyrosine phosphorylation of STAT3 and agonist-selective serine phosphorylation via sustained stimulation of mitogen-activated protein kinase. Resultant effects on cell proliferation

12 March 2024

50

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Activation of Stat3 by v-Src is through a Ras-independent pathway

12 March 2024

51

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

c-Fes tyrosine kinase binds to and activates STAT3 after granulocyte-macrophage colony-stimulating factor stimulation.

12 March 2024

52

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

12 March 2024

53

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

In vitro activation of Stat3 by epidermal growth factor receptor kinase

12 March 2024

54

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Activation of STAT3 by the c-Fes protein-tyrosine kinase

12 March 2024

55

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells

12 March 2024

56

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Curcumin is a non-competitive and selective inhibitor of phosphorylase kinase

12 March 2024

57

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells

12 March 2024

59

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

12 March 2024

60

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

STATs in oncogenesis

61

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

Stat3 as an oncogene

62

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

STAT signaling in head and neck cancer

12 March 2024

65

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma

12 March 2024

67

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma

12 March 2024

68

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Role of curcumin in idiopathic inflammatory orbital pseudotumours

12 March 2024

69

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

Efficacy of curcumin in the management of chronic anterior uveitis

12 March 2024

70

1 reference

https://api.crossref.org/works/10.4049/JIMMUNOL.171.7.3863

12 March 2024

Identifiers

1 reference

22 September 2017

1 reference