(Q35746546)

10 August 2017

title

Transgenic expression of cyclin-dependent kinase 4 results in epidermal hyperplasia, hypertrophy, and severe dermal fibrosis (English)

1 reference

10 August 2017

author name string

P L Miliani de Marval

1

1 reference

10 August 2017

I B Gimenez-Conti

2

1 reference

10 August 2017

M LaCava

3

1 reference

10 August 2017

L A Martinez

4

1 reference

10 August 2017

C J Conti

5

1 reference

10 August 2017

M L Rodriguez-Puebla

6

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 July 2001

1 reference

The American Journal of Pathology

10 August 2017

published in

1 reference

10 August 2017

volume

159

1 reference

10 August 2017

issue

1

1 reference

10 August 2017

page(s)

369-379

1 reference

Cyclin D2 overexpression in transgenic mice induces thymic and epidermal hyperplasia whereas cyclin D3 expression results only in epidermal hyperplasia

10 August 2017

cites work

1 reference

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12 July 2018

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Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair

12 July 2018

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

12 July 2018

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

12 July 2018

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12 July 2018

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12 July 2018

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P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor

12 July 2018

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Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes

12 July 2018

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Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

12 July 2018

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Modeling mutations in the G1 arrest pathway in human gliomas: overexpression of CDK4 but not loss of INK4a-ARF induces hyperploidy in cultured mouse astrocytes

12 July 2018

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Directed expression of keratin 16 to the progenitor basal cells of transgenic mouse skin delays skin maturation

12 July 2018

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12 July 2018

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12 July 2018

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Synchronized proliferation induced by 12-O-tetradecanoylphorbol-13-acetate treatment of mouse skin: an in vivo model for cell cycle regulation

12 July 2018

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Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4

12 July 2018

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Identification of CDK4 sequences involved in cyclin D1 and p16 binding

12 July 2018

1 reference

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Histone deacetylase activity is required for full transcriptional repression by mSin3A

12 July 2018

1 reference

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CDK-independent activation of estrogen receptor by cyclin D1

12 July 2018

1 reference

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The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2

12 July 2018

1 reference

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Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis

12 July 2018

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Why are there so many CDK inhibitors?

12 July 2018

1 reference

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Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

p21 is a universal inhibitor of cyclin kinases

12 July 2018

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Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins

12 July 2018

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12 July 2018

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12 July 2018

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Rarity of somatic and germline mutations of the cyclin-dependent kinase 4 inhibitor gene, CDK4I, in melanoma

12 July 2018

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Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

12 July 2018

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A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

12 July 2018

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Role of the cyclin-dependent kinase inhibitors in the development of cancer.

12 July 2018

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12 July 2018

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Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

12 July 2018

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Sequences 5' of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Sequential expression of mRNA-encoded keratin sets in neonatal mouse epidermis: Basal cells with properties of terminally differentiating cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Keratin gene expression in mouse epidermis and cultured epidermal cells

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Differences of expression of cytokeratin polypeptides in various epithelial skin tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Keratin expression in mouse epidermal tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

E2F: a link between the Rb tumor suppressor protein and viral oncoproteins

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850398

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

25 September 2018

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961703-8

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7 January 2021

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https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961703-8

Deregulated expression of cell-cycle proteins during premalignant progression in SENCAR mouse skin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961703-8

Rescue of Cyclin D1 Deficiency by Knockin Cyclin E

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2961703-8

Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11438484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11438484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cyclin D1 overexpression in mouse epidermis increases cyclin-dependent kinase activity and cell proliferation in vivo but does not affect skin tumor development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11438484

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)61703-8

1 reference

10 August 2017

1 reference

10 August 2017

1 reference