(Q35748649)

10 August 2017

Initial testing (stage 1) by the pediatric preclinical testing program of RO4929097, a γ-secretase inhibitor targeting notch signaling (English)

1 reference

10 August 2017

2

Richard Gorlick

1 reference

10 August 2017

11

Peter J Houghton

1 reference

10 August 2017

9

Min H Kang

1 reference

10 August 2017

4

John M Maris

1 reference

10 August 2017

12

Malcolm A Smith

1 reference

10 August 2017

7

Raushan T Kurmasheva

1 reference

10 August 2017

5

Richard Lock

1 reference

10 August 2017

1

E Anders Kolb

1 reference

10 August 2017

3

Stephen T Keir

1 reference

10 August 2017

6

Hernan Carol

1 reference

10 August 2017

C Patrick Reynolds

8

1 reference

PubMed ID

22052798

10 August 2017

Jianrong Wu

series ordinal

10

1 reference

PubMed ID

22052798

10 August 2017

language of work or name

1 reference

16 August 2011

1 reference

10 August 2017

Pediatric Blood Cancer

1 reference

10 August 2017

58

1 reference

10 August 2017

5

1 reference

10 August 2017

815-818

1 reference

Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Notch signaling in the regulation of stem cell self-renewal and differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Notch signaling: emerging molecular targets for cancer therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Notch signaling contributes to the pathogenesis of human osteosarcomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Molecular characterization of the pediatric preclinical testing panel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Critical role of notch signaling in osteosarcoma invasion and metastasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Notch signaling in leukemia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Inhibition of notch signaling induces neural differentiation in Ewing sarcoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Experimental chemotherapy of human medulloblastoma cell lines and transplantable xenografts with bifunctional alkylating agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Preclinical profile of a potent gamma-secretase inhibitor targeting notch signaling with in vivo efficacy and pharmacodynamic properties

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

The pediatric preclinical testing program: description of models and early testing results.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3276746

25 September 2018

Identifiers

DOI

10.1002/PBC.23290

1 reference

10 August 2017

1 reference

10 August 2017

1 reference

PubMed ID

22052798