(Q35750188)

10 August 2017

title

Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo (English)

1 reference

10 August 2017

11

Iver A Langmoen

1 reference

10 August 2017

Mrinal Joel

1

1 reference

10 August 2017

Awais A Mughal

2

1 reference

10 August 2017

Zanina Grieg

3

1 reference

10 August 2017

Wayne Murrell

4

1 reference

10 August 2017

Sheryl Palmero

5

1 reference

10 August 2017

Birthe Mikkelsen

6

1 reference

10 August 2017

Hege B Fjerdingstad

7

1 reference

10 August 2017

Cecilie J Sandberg

8

1 reference

10 August 2017

Jinan Behnan

9

1 reference

10 August 2017

Joel C Glover

10

1 reference

10 August 2017

Biljana Stangeland

12

1 reference

10 August 2017

publication date

17 June 2015

1 reference

10 August 2017

1 reference

10 August 2017

volume

14

1 reference

10 August 2017

page(s)

121

1 reference

Creative Commons Attribution 4.0 International

10 August 2017

copyright license

start time

17 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer.

12 July 2018

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12 July 2018

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PBK/TOPK interacts with the DBD domain of tumor suppressor p53 and modulates expression of transcriptional targets including p21

12 July 2018

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Critical roles of T-LAK cell-originated protein kinase in cytokinesis

12 July 2018

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Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells

12 July 2018

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A mitotic kinase TOPK enhances Cdk1/cyclin B1-dependent phosphorylation of PRC1 and promotes cytokinesis

12 July 2018

1 reference

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PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response

12 July 2018

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Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells.

12 July 2018

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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

12 July 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

12 July 2018

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PDZ-binding kinase/T-LAK cell-originated protein kinase, a putative cancer/testis antigen with an oncogenic activity in breast cancer

12 July 2018

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12 July 2018

Brain tumour stem cells

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

12 July 2018

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Expression and phosphorylation of TOPK during spermatogenesis

12 July 2018

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PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase

12 July 2018

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12 July 2018

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Identification of human brain tumour initiating cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Characterization of a MAPKK-like protein kinase TOPK

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Current management of glioblastoma multiforme

12 July 2018

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Applying the principles of stem-cell biology to cancer

12 July 2018

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12 July 2018

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Identification of a cancer stem cell in human brain tumors

12 July 2018

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12 July 2018

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PBK/TOPK is a novel mitotic kinase which is upregulated in Burkitt's lymphoma and other highly proliferative malignant cells

12 July 2018

1 reference

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Cloning and expression of a novel MAPKK-like protein kinase, lymphokine-activated killer T-cell-originated protein kinase, specifically expressed in the testis and activated lymphoid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Brain tumor survival: results from the National Cancer Data Base

12 July 2018

1 reference

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12 July 2018

1 reference

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

12 July 2018

1 reference

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Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

c-Myc and E2F1 drive PBK/TOPK expression in high-grade malignant lymphomas

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Aqp 9 and brain tumour stem cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Overexpression of T-LAK cell-originated protein kinase predicts poor prognosis in patients with stage I lung adenocarcinoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Overall survival, prognostic factors, and repeated surgery in a consecutive series of 516 patients with glioblastoma multiforme

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

Transplantation of stem cells from the adult human brain to the adult rat brain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470057

RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12943-015-0398-X

A comparison between stem cells from the adult human brain and from brain tumors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26081429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Avoiding cross hybridization by choosing nonredundant targets on cDNA arrays

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26081429

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12943-015-0398-X

1 reference

Dimensions Publication ID

10 August 2017

0 references

1 reference

10 August 2017

1 reference