(Q35758346)

10 August 2017

title

Highly reduced protection against Streptococcus pneumoniae after deletion of a single heavy chain gene in mouse (English)

1 reference

10 August 2017

main subject

phosphocholine cation

1 reference

ChEBI release 2020-05-28

ChEBI ID

18132

Streptococcus pneumoniae

1 reference

8

D L Longo

1 reference

10 August 2017

Q S Mi

1

1 reference

10 August 2017

L Zhou

2

1 reference

10 August 2017

D H Schulze

3

1 reference

10 August 2017

R T Fischer

4

1 reference

10 August 2017

A Lustig

5

1 reference

10 August 2017

L J Rezanka

6

1 reference

10 August 2017

D M Donovan

7

1 reference

10 August 2017

J J Kenny

9

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 May 2000

1 reference

10 August 2017

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

10 August 2017

volume

97

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10 August 2017

issue

11

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10 August 2017

page(s)

6031-6036

1 reference

Enhancement and destruction of antibody function by somatic mutation: unequal occurrence is controlled by V gene combinatorial associations.

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Protection of mice from infection with Streptococcus pneumoniae by anti-phosphocholine antibody

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Epidemiological studies of Streptococcus pneumoniae in infants: development of antibody to phosphocholine.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Antigen-binding myeloma proteins in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Phosphorylcholine antibodies in pulmonary infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Receptor-mediated elimination of phosphocholine-specific B cells in x-linked immune-deficient mice.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Human anti-phosphorylcholine antibodies share idiotopes and are self-binding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Mouse antibody to phosphocholine can protect mice from infection with mouse-virulent human isolates of Streptococcus pneumoniae

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Antigen binding and idiotype analysis of antibodies obtained after electroporation of heavy and light chain genes encoding phosphocholine-specific antibodies: a model for T15-idiotype dominance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

The “patchy” immunodeficiency of CBA/N mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Idiotype-specific neonatal suppression of phosphorylcholine-responsive B cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

The monoclonal anti-phosphorylcholine antibody response in several murine strains: genetic implications of a diverse repertoire

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Pneumococcal polysaccharide immunization in infants and children

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Immunologic Epitope, Gene, and Immunity Involved in Pneumococcal Glycoconjugate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Sequence changes at the V-D junction of the VH1 heavy chain of anti-phosphocholine antibodies alter binding to and protection against Streptococcus pneumoniae

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Induction of phosphocholine-specific antibodies in X-linked immune deficient mice: in vivo protection against a Streptococcus pneumoniae challenge

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Immunologic memory to phosphorylcholine. II. PC-KLH induces two antibody populations that dominate different isotypes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Clonal restriction of the immune response to phosphorylcholine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Inefficacy of pneumococcal vaccine in a high-risk population

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Genetic control of the susceptibility to pneumococcal infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Recent developments in bacterial conjugate vaccines

12 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

The protective efficacy of polyvalent pneumococcal polysaccharide vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Repertoire diversity of antibody response to bacterial antigens in aged mice. III. Phosphorylcholine antibody from young and aged mice differ in structure and protective activity against infection with Streptococcus pneumoniae

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Cross-reactive antibodies have both protective and pathogenic potential

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18553

Pathogenesis of Pneumococcal Infection

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Specific inhibition of plaque formation to phosphorylcholine by antibody against antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Antibody protection in aging: influence of idiotypic repertoire and antibody binding activity to a bacterial antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Natural and vaccine-related immunity to Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

A study of autologous anti-idiotypic antibody-forming cells in mice of different ages and genetic backgrounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Antibodies against pneumococcal C-polysaccharide are not protective

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Impaired Antibody Response to Pneumococcal Capsular Polysaccharides and Phosphorylcholine in Adult Patients with a History of Bacteremic Pneumococcal Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Age-dependent IgG subclass distribution of phosphocholine antibodies in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Rat anti-T15 monoclonal antibodies with specificity for VH- and VH-VL epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

A Mouse Monoclonal Antibody Specific for an Allotypic Determinant of theIghaAllele of Murine IgM: Genetic and Functional Analysis of Igh-6a Epitopes Using Anti-IgM Monoclonal Antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Inhibition of Self-Binding Antibodies (Autobodies) by a V H -Derived Peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.110039497

Subpopulations of antibodies to phosphocholine in human serum

21 January 2018

1 reference

12 December 2020

Repertoire diversity of antibody response to bacterial antigens in aged mice. II. Phosphorylcholine-antibody in young and aged mice differ in both VH/VL gene repertoire and in specificity

1 reference

12 December 2020

Repertoire diversity of antibody response to bacterial antigens in aged mice. IV. Study of VH and VL gene utilization in splenic antibody foci by in situ hybridization

1 reference

12 December 2020

A novel phosphocholine antigen protects both normal and X-linked immune deficient mice against Streptococcus pneumoniae. Comparison of the 6-O-phosphocholine hydroxyhexanoate-conjugate with other phosphocholine-containing vaccines

1 reference

12 December 2020

Clonal nature of the immune response to phosphocholine. VII. Evidence throughout inbred mice for molecular similarities among antibodies bearing the T15 idiotype

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.110039497

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference