(Q35759128)

10 August 2017

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title

A review of assay methods for cyclosporin. Clinical implications (English)

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10 August 2017

K. T. Kivistö

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1511535

3 October 2022

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1511535

3 October 2022

publication date

1 September 1992

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Clinical Pharmacokinetics

10 August 2017

published in

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10 August 2017

volume

23

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10 August 2017

issue

3

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10 August 2017

page(s)

173-190

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https://scigraph.springernature.com/pub.10.2165/00003088-199223030-00002

10 August 2017

exact match

0 references

cites work

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Minimal low dosage of cyclosporine therapy in renal transplantation by careful monitoring of high-performance liquid chromatography whole blood trough levels

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Individualization of cyclosporine therapy using pharmacokinetic and pharmacodynamic parameters

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Cyclosporine and metabolites in blood from renal allograft recipients with nephrotoxicity, rejection, or good renal function: comparative high-performance liquid chromatography and monoclonal radioimmunoassay studies

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12 December 2020

Chemiluminescence immunoassay of cyclosporine in whole blood

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12 December 2020

Abbott TDx monoclonal antibody assay evaluated for measuring cyclosporine in whole blood

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12 December 2020

Association of very high blood levels of cyclosporin metabolites with clinical complications after liver transplantation

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12 December 2020

Consensus document: Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine

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12 December 2020

Immunosuppressive activity of cyclosporine metabolites compared and characterized by mass spectroscopy and nuclear magnetic resonance

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12 December 2020

The relationship between cyclosporine pharmacokinetic parameters and subsequent acute rejection in renal transplant recipients

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12 December 2020

A critical analysis of serum and urine interleukin-2 receptor assays in renal allograft recipients

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12 December 2020

Neurotoxicity caused by a high cyclosporine metabolite level

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12 December 2020

Comparative analyses of cyclosporine in whole blood and plasma by radioimmunoassay, fluorescence polarization immunoassay, and high-performance liquid chromatography

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12 December 2020

Comparison of cyclosporine blood levels measured by radioimmunoassay and TDx assay using monoclonal antibodies

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12 December 2020

Measurement of cyclosporine in plasma from patients with various transplants: HPLC radioimmunoassay with a specific monoclonal antibody compared

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12 December 2020

Cyclosporin A-induced side effects in renal transplantation are related to the ratio of nonspecific/specific cyclosporin blood trough levels as analysed by radioimmunoassay

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12 December 2020

The continuing need for quality assessment of cyclosporine measurement

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12 December 2020

Cyclosporine in autoimmune diseases

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12 December 2020

Automated assay specific for cyclosporine in whole blood, with use of a chromium dioxide particle column

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12 December 2020

High-performance liquid chromatographic column-switching method for two cyclosporine metabolites in blood

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12 December 2020

Cyclosporine monitoring in renal transplantation: area under the curve monitoring is superior to trough-level monitoring

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12 December 2020

The use of routinely available clinical data in differentiating renal allograft rejection from cyclosporine nephrotoxicity

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12 December 2020

Liver transplantation in Birmingham--use of cyclosporine--clinical correlations with drug measurements

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12 December 2020

The value of serial serum trough cyclosporine levels in human renal transplantation

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12 December 2020

Optimized high-performance liquid chromatographic method for the analysis of cyclosporine and three of its metabolites in blood and urine

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12 December 2020

Cyclosporine monitoring in autoimmune and other diseases

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12 December 2020

Liquid-chromatographic measurement of cyclosporin A and its metabolites in blood, bile, and urine

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12 December 2020

An increased incidence of late acute rejection episodes in cadaver renal allograft recipients given azathioprine, cyclosporine, and prednisone

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12 December 2020

A preliminary study to evaluate an in vitro assay for determining patient whole blood immunosuppressive cyclosporine A and metabolite activity: comparison with cytosolic binding assays using cyclophilin or a 50-kilodalton binding protein, and the Ab

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12 December 2020

Comparison of cyclosporin A measurement in whole blood by six different methods.

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12 December 2020

Use of a monoclonal antibody for the therapeutic monitoring of cyclosporine in plasma and whole blood

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12 December 2020

Cyclosporine: assay by HPLC and assay with monoclonal antibodies equivalent?

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12 December 2020

Determination of cyclosporine by a competitive binding assay with cyclophilin

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12 December 2020

Cyclophilin binding: a more accurate measure of cyclosporine immunosuppressive activity after renal transplantation

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12 December 2020

Therapeutic cyclosporine monitoring: comparison of radioimmunoassay and high-performance liquid chromatography methods in organ transplant recipients

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12 December 2020

Calibration problems with the 125I immunoassay for measuring cyclosporin A

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Pharmacology of cyclosporine (sandimmune). III. Immunochemistry and monitoring

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12 December 2020

The clinical significance of cyclosporine metabolites

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12 December 2020

Trough levels and concentration time curves of cyclosporine in patients undergoing renal transplantation

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12 December 2020

An evaluation of cyclosporine monitoring by nonselective fluorescence polarization immunoassay

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12 December 2020

Immunosuppressive properties of cyclosporin metabolites

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12 December 2020

A comparison of the clinical utility of the radioimmunoassay, high-performance liquid chromatography, and TDx cyclosporine assays in outpatient renal transplant recipients

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12 December 2020

Laboratory monitoring of cyclosporine levels: guidelines for the dermatologist

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12 December 2020

Comparison of the utility of 3H-based specific monoclonal antibody assay on whole blood samples with the fluorescence polarization nonspecific immunoassay on serum samples for diagnosis of adverse events in renal transplant patients

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12 December 2020

Toxicity of cyclosporine metabolites

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12 December 2020

Role of lipoproteins and erythrocytes in the in vitro binding and distribution of cyclosporin A in the blood

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12 December 2020

Canadian Consensus Meeting on cyclosporine monitoring: report of the consensus panel.

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12 December 2020

Quality assessment of cyclosporine measurements: comparison of current methods

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12 December 2020

New Zealand multicentre comparison of monoclonal (Sandimmun) versus polyclonal (cyclosporine-RIA) radioimmunoassays for cyclosporine blood monitoring

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12 December 2020

A prospective study of cyclosporine concentration in relation to its therapeutic effect and toxicity after renal transplantation

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12 December 2020

An evaluation of the cyclosporine and metabolites whole blood TDx assay

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12 December 2020

Steady-state concentrations of cyclosporine for therapeutic monitoring

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12 December 2020

The impact of cyclosporine on the practice of renal transplantation

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12 December 2020

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA.

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12 December 2020

Monitoring of blood levels of cyclosporine in renal and cardiac transplant recipients--comparison of HPLC to Incstar CYCLO-Trac SP RIA.

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12 December 2020

Separation of cyclosporine metabolites: evaluation of high pressure liquid chromatographic column performance

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12 December 2020

Cyclosporine monitoring in liver allograft recipients: two distinct patterns of blood level derangement associated with nephrotoxicity

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12 December 2020

Monitoring of cyclosporine by serial posttransplant pharmacokinetic studies in renal transplant patients

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12 December 2020

Calibration of 125I immunoassay measuring cyclosporin A

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12 December 2020

Clinical pharmacokinetics in organ transplant patients

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12 December 2020

Cyclosporin assay techniques. Accuracy and reproducibility variables impacting on measurements

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12 December 2020

Area-under-the-curve monitoring of cyclosporine therapy: performance of different assay methods and their target concentrations

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12 December 2020

Intravenous cyclosporine kinetics in renal failure

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12 December 2020

Potential of monoclonal antibodies to improve therapeutic monitoring of cyclosporine

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12 December 2020

Cyclosporine blood level monitoring: the early posttransplant period

1 reference

12 December 2020

Comparison of nonspecific radioimmunoassay, high-performance liquid chromatography, and fluorescence polarization immunoassay for cyclosporine monitoring in renal transplantation

1 reference

12 December 2020

Studies of cyclosporine blood levels: analysis, clinical utility, pharmacokinetics, metabolites, and chronopharmacology

1 reference

12 December 2020

Deposition of nine metabolites of cyclosporine in human tissues, bile, urine, and whole blood

1 reference

12 December 2020

Monitoring of cyclosporine blood levels with polyclonal and monoclonal assays during episodes of renal graft dysfunction

1 reference

12 December 2020

Cyclosporin: pharmacokinetics and detailed studies of plasma and erythrocyte binding during intravenous and oral administration.

1 reference

12 December 2020

Cyclophilin binding: a receptor-mediated approach to monitoring cyclosporine immunosuppressive activity following organ transplantation

1 reference

12 December 2020

Improved liquid-chromatographic determination of cyclosporine and its metabolites in blood

1 reference

12 December 2020

Three commercial polyclonal immunoassays for cyclosporine in whole blood compared: 1. Results with patients' specimens.

1 reference

12 December 2020

Cyclosporine A monitoring by radioimmunoassay (RIA) and high-performance liquid chromatography (HPLC) after liver transplantation: influence of route of administration and of liver function on the RIA:HPLC ratio

1 reference

12 December 2020

Therapeutic drug monitoring of cyclosporin. Practical applications and limitations

1 reference

12 December 2020

Area under the curve monitoring of cyclosporine therapy: the early posttransplant period.

1 reference

12 December 2020

Cyclosporine nephrotoxicity is minimized by adjusting dosage on the basis of drug concentration in blood

1 reference

12 December 2020

Abbott TDx "selective" assay overestimates cyclosporine in whole blood.

1 reference

12 December 2020

Cyclosporine monitoring

1 reference

12 December 2020

Monoclonal fluorescence polarization immunoassay evaluated for monitoring cyclosporine in whole blood after kidney, heart, and liver transplantation

1 reference

12 December 2020

Analytical performance of EMIT cyclosporine assay evaluated

1 reference

12 December 2020

Distribution of cyclosporin A metabolites among plasma and cells in whole blood: effect of temperature, hematocrit, and metabolite concentration

1 reference

12 December 2020

Monoclonal antibodies for radioimmunoassay of cyclosporine: a multicenter comparison of their performance with the Sandoz polyclonal radioimmunoassay kit.

1 reference

12 December 2020

Immunological monitoring in cyclosporine-treated patients

1 reference

12 December 2020

Cyclosporine metabolites: are they active?

1 reference

12 December 2020

Blood cyclosporin concentrations and renal allograft dysfunction

1 reference

12 December 2020

Therapeutic monitoring of cyclosporine: impact of a change in standards on 125I-monoclonal RIA performance in comparison with liquid chromatography

1 reference

12 December 2020

Evaluation of Abbott TDx monoclonal assay of cyclosporine in whole blood

1 reference

12 December 2020

Optimization of cyclosporine therapy in renal transplantation by a pharmacokinetic strategy

1 reference

12 December 2020

Evaluation of the Incstar Cyclo-Trac sp kit for the determination of cyclosporine in blood

1 reference

12 December 2020

Cyclosporine determinations in heart and kidney transplant patients: comparison of high-performance liquid chromatography, polyclonal, and monoclonal methods

1 reference

12 December 2020

Long-term cyclosporine pharmacokinetic changes in renal transplant recipients: effects of binding and metabolism

1 reference

12 December 2020

Determination of cyclosporine concentrations with monoclonal antibodies

1 reference

12 December 2020

Cyclosporine trough concentration monitoring in liver transplant patients

1 reference

12 December 2020

Cyclosporine blood concentrations determined by specific versus nonspecific assay methods

1 reference

12 December 2020

Adjustment of cyclosporine dosage in renal transplant patients based on concentration measured specifically in whole blood: clinical outcome results and diagnostic utility

1 reference

12 December 2020

Comparison of cyclosporine (CSA) blood levels and RIA/HPLC ratios among renal transplant patients with normal allograft function, CSA nephrotoxicity or rejection

1 reference

12 December 2020

A monoclonal antibody fluorescent polarization immunoassay for cyclosporine

1 reference

12 December 2020

1 reference

12 December 2020

Pharmacokinetic drug interactions with cyclosporin (Part II).

1 reference

12 December 2020

Specific 3H radioimmunoassay with a monoclonal antibody for monitoring cyclosporine in blood.

1 reference

12 December 2020

Comment on cyclosporine assay techniques: an attempt for recommendations

1 reference

12 December 2020

Quality assessment of cyclosporine monitoring by 32 Canadian laboratories

1 reference

12 December 2020

Comparison of specific radioimmunoassays for cyclosporine

1 reference

12 December 2020

Should cyclosporine be continued indefinitely?

1 reference

12 December 2020

A limited sampling strategy for the measurement of cyclosporine AUC

1 reference

12 December 2020

New automated high-performance liquid chromatographic analysis of cyclosporin A and G in human serum

1 reference

12 December 2020

Interleukin-2 assay in serum and urine as a means of monitoring pancreatic allograft rejection

1 reference

12 December 2020

Cyclosporine pharmacokinetics in liver transplant recipients: evaluation of results using both polyclonal radioimmunoassay and liquid chromatographic analysis

1 reference

12 December 2020

Cyclosporine monitoring by fluorescence polarization immunoassay

1 reference

12 December 2020

Cyclosporin metabolites and central-nervous-system toxicity.

1 reference

12 December 2020

Clinical pharmacokinetics of cyclosporin

1 reference

12 December 2020

Relationship of cyclosporine pharmacokinetic parameters to clinical events in human renal transplantation.

1 reference

12 December 2020

Assay methods for cyclosporine monitoring following liver transplantation

1 reference

12 December 2020

Ciclosporin metabolite pattern in blood and urine of kidney graft patients in relation to liver function

1 reference

12 December 2020

A rapid and specific assay for the du Pont aca discrete clinical analyzer, performed directly on whole blood

1 reference

12 December 2020

Value of cyclosporine measurements in renal transplant recipients immunosuppressed with triple therapy.

1 reference

12 December 2020

The impact of steady-state cyclosporine concentrations on renal allograft outcome

1 reference

12 December 2020

Cross-correlation of cyclosporine concentrations and biochemical measures of kidney and liver function in heart and heart-lung transplant recipients

1 reference

12 December 2020

Soluble interleukin-2 receptors in serum and bile of liver transplant recipients

1 reference

12 December 2020

Pharmacokinetic drug interactions with cyclosporin (Part I).

1 reference

12 December 2020

Clinical evaluation and therapeutic range of cyclosporine A as monitored by FPIA in kidney transplantation

1 reference

12 December 2020

Sequential determinations of urinary cytology and plasma and urinary lymphokines in the management of renal allograft recipients

1 reference

12 December 2020

Clinical correlations of cyclosporine HPLC and FPIA levels in renal transplant recipients

1 reference

12 December 2020

Cross-reactivity of cyclosporine metabolites in two different radioimmunoassays in which the same specific monoclonal antibody is used

1 reference

12 December 2020

Critical issues in cyclosporine monitoring: report of the Task Force on Cyclosporine Monitoring

1 reference

12 December 2020

Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring

1 reference

12 December 2020

Routine monitoring of cyclosporine in whole blood and in kidney tissue using high performance liquid chromatography

1 reference

12 December 2020

Interleukin-2 receptor as an immunodiagnostic tool to differentiate rejection from nephrotoxicity

1 reference

12 December 2020

Cyclosporine: structure, pharmacokinetics, and therapeutic drug monitoring

1 reference

12 December 2020

Measurement of cyclosporine A by a specific radioimmunoassay with a monoclonal antibody and 125I tracer

1 reference

12 December 2020

Comparison of ELISA and a flow cytometric method in the daily monitoring of soluble interleukin 2 receptors in liver transplant recipients

1 reference

12 December 2020

Cyclosporine therapy for psoriasis: serum creatinine measurements are an unreliable predictor of decreased renal function.

1 reference

12 December 2020

On the dose dependency of cyclosporin A absorption and disposition in healthy volunteers

1 reference

12 December 2020

Measurement of cyclosporine concentrations in whole blood: HPLC and radioimmunoassay with a specific monoclonal antibody and 3H- or 125I-labeled ligand compared

1 reference

12 December 2020

Predictive value of cyclosporin A level for efficacy or renal dysfunction in psoriasis

1 reference

12 December 2020

Therapeutic monitoring for cyclosporine: difficulties in establishing a therapeutic window

1 reference

12 December 2020

Cyclosporine Monitoring and Pharmacokinetics in Pediatrie Liver Transplant Patients

1 reference

12 December 2020

Estimation of ciclosporin levels using a ciclophilin-binding assay

1 reference

12 December 2020

Soluble interleukin-2 receptor level as an indicator of liver allograft rejection

1 reference

12 December 2020

Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation

1 reference

12 December 2020

Influence of different parameters for the monitoring of cyclosporine

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12 December 2020

Intraindividual variability in the relative systemic availability of cyclosporin after oral dosing

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12 December 2020

10.2165/00003088-199223030-00002

Identifiers

DOI

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Dimensions Publication ID

10 August 2017

1034310548

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