(Q38018027)

27 August 2017

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title

Pharmacokinetic drug interactions with cyclosporin (Part II). (English)

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27 August 2017

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Yee GC

1

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PubMed ID

2268987

27 August 2017

McGuire TR

series ordinal

2

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27 August 2017

1 November 1990

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Clinical Pharmacokinetics

27 August 2017

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27 August 2017

19

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27 August 2017

5

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27 August 2017

400-415

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https://scigraph.springernature.com/pub.10.2165/00003088-199019050-00004

27 August 2017

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cites work

Erythromycin-cyclosporin interaction

1 reference

12 December 2020

Co-administration of ciprofloxacin and cyclosporin: lack of evidence for a pharmacokinetic interaction

1 reference

12 December 2020

The effect of ciprofloxacin on antipyrine metabolism

1 reference

12 December 2020

Effect of josamycin on plasma cyclosporine levels

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12 December 2020

High cyclosporin levels after bone marrow transplantation associated with hypertriglyceridaemia

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12 December 2020

Fluconazole is a potent inhibitor of antipyrine metabolism in vivo in mice.

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12 December 2020

Effect of bile on cyclosporin absorption in liver transplant patients

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12 December 2020

Ketoconazole, cyclosporin metabolism, and renal transplantation

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12 December 2020

Effects of nitrendipine on blood pressure and blood ciclosporin A level in patients with posttransplant hypertension

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12 December 2020

Ciclosporin-nicardipine interaction

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12 December 2020

Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme

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12 December 2020

Administration of somatostatin analog (SMS 201-995) in the treatment of a fistula occurring after pancreas transplantation. Interference with cyclosporine immunosuppression

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12 December 2020

Inhibition of drug metabolism by quinolone antibiotics.

1 reference

12 December 2020

Norfloxacin-cyclosporine interaction

1 reference

12 December 2020

Cyclosporine kinetics in renal transplantation

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12 December 2020

Cyclosporine (cyclosporin A) pharmacokinetics in renal transplant patients receiving ciprofloxacin

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12 December 2020

Clinically important interaction of cyclosporine and erythromycin

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12 December 2020

Cyclosporin interaction with danazol and norethisterone

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12 December 2020

Effect of erythromycin on cyclosporine levels.

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12 December 2020

Possible interaction between cyclosporine and erythromycin

1 reference

12 December 2020

Calcium channel antagonists and cyclosporine metabolism: in vitro studies with human liver microsomes

1 reference

12 December 2020

Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily

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12 December 2020

Inhibition of cyclosporine metabolism by other drugs in vitro

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12 December 2020

INTERACTION OF FLUCONAZOLE WITH CYCLOSPORIN

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12 December 2020

Use of cyclosporine and ketoconazole without nephrotoxicity in two heart transplant recipients

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12 December 2020

CYCLOSPORIN INTERACTION WITH KETOCONAZOLE AND MELPHALAN

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12 December 2020

Cyclosporine-ketoconazole: a potentially dangerous drug-drug interaction

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12 December 2020

Cyclosporine plasma levels in renal transplant patients. Association with renal toxicity and allograft rejection

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12 December 2020

Influence of diltiazem on cyclosporin clearance

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12 December 2020

Sulindac-induced elevation of serum cyclosporine concentration

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12 December 2020

Central nervous system toxicity after liver transplantation. The role of cyclosporine and cholesterol.

1 reference

12 December 2020

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of [...]

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12 December 2020

Influence of prednisolone on antipyrine and chloramphenicol disposition in rabbits

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12 December 2020

Cyclosporine blood concentrations in the management of renal transplant recipients

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12 December 2020

Diltiazem treatment impairs hepatic drug oxidation: studies of antipyrine

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12 December 2020

Influence of erythromycin on cyclosporine pharmacokinetics

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12 December 2020

Cyclosporine-associated chronic nephropathy

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12 December 2020

The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

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12 December 2020

Cyclosporin-erythromycin interaction in renal transplant patients

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12 December 2020

The effect of nifedipine on graft function in renal allograft recipients treated with cyclosporin A

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12 December 2020

Cyclosporine-induced renal dysfunction in human renal allograft recipients.

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12 December 2020

The effect of cyclosporine on the pharmacokinetics of prednisolone in renal transplant patients

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12 December 2020

Ranitidine, cimetidine, and the cyclosporine-treated recipient

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12 December 2020

Influence of the hepatic drug-metabolizing enzyme-inducer phenobarbitone on cyclosporine nephrotoxicity and hepatotoxicity in renal-allografted rats

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12 December 2020

Itraconazole and cyclosporin nephrotoxicity

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12 December 2020

Cyclosporin and intravenous sulphadimidine and trimethoprim therapy

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12 December 2020

Effect of danazol on cyclosporine pharmacokinetics

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12 December 2020

Cyclosporine-rifampin drug interaction

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12 December 2020

Effects of H2-receptor antagonists on renal function in cyclosporine-treated renal transplant patients

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12 December 2020

Absence of significant interaction of fluconazole with cyclosporin

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12 December 2020

The effect of food on cyclosporine absorption

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12 December 2020

Role of lipoproteins and erythrocytes in the in vitro binding and distribution of cyclosporin A in the blood

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12 December 2020

Nephrotoxicity of cyclosporin A in bone-marrow transplantation

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12 December 2020

Inhibition of prednisolone metabolism by cyclosporine in kidney-transplanted patients

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12 December 2020

Interaction between cyclosporin and erythromycin in a kidney transplant patient

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12 December 2020

Effect of somatostatin analogue (SMS201-995) on cyclosporine levels

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12 December 2020

Interaction between phenytoin and cyclosporine following organ transplantation

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12 December 2020

Metabolism of cyclosporin A. II. Implication of the macrolide antibiotic inducible cytochrome P-450 3c from rabbit liver microsomes

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12 December 2020

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA.

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12 December 2020

Cyclosporin and rifampicin in renal transplantation

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12 December 2020

Acetazolamide and cyclosporine

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12 December 2020

Concomitant cyclosporin and ketoconazole

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12 December 2020

Evidence that cyclosporine does not affect the metabolism of prednisolone after renal transplantation

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12 December 2020

Serious interaction between cyclosporin A and sulphadimidine

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12 December 2020

The effect of ethanol on serum cyclosporine A levels in renal transplant recipients

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12 December 2020

Effect of the calcium channel blocker diltiazem on cyclosporine A blood levels and dose requirements

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12 December 2020

Low cyclosporin A blood levels and acute graft rejection in a renal transplant recipient during rifampin treatment

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12 December 2020

Deposition of nine metabolites of cyclosporine in human tissues, bile, urine, and whole blood

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12 December 2020

Cyclosporin-erythromycin interaction in normal subjects.

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12 December 2020

Evaluation of cyclosporin-verapamil interaction, with observations on parent cyclosporin and metabolites

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12 December 2020

Effect of rifampicin on cyclosporin A blood levels in a renal transplant recipient

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12 December 2020

Interaction of cyclosporin and itraconazole

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12 December 2020

Toxicity of cyclosporine during treatment with androgens.

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12 December 2020

Pharmacokinetic interaction between cyclosporin and diltiazem

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12 December 2020

Therapeutic drug monitoring of cyclosporin. Practical applications and limitations

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12 December 2020

Increased cyclosporine blood concentrations due to verapamil administration.

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12 December 2020

Time course of cyclosporin/itraconazole interaction

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12 December 2020

The free fraction of cyclosporine in plasma: clinical findings with a new method

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12 December 2020

Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil.

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12 December 2020

Cyclosporin-diltiazem interaction: comparison of cyclosporin levels measured with two monoclonal antibodies

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12 December 2020

The antagonistic effect of rifampin upon cyclosporine bioavailability

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12 December 2020

Reversible acute cyclosporin nephrotoxicity induced by colchicine administration.

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12 December 2020

The effects of erythromycin in patients treated with cyclosporine

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12 December 2020

Age-dependent cyclosporine: pharmacokinetics in marrow transplant recipients

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12 December 2020

Commentary: a physiological approach to hepatic drug clearance

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12 December 2020

The effects of spiramycin on plasma cyclosporin A concentrations in heart transplant patients

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12 December 2020

Optimization of cyclosporine therapy in renal transplantation by a pharmacokinetic strategy

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12 December 2020

Association of the absence of steroid therapy with increased cyclosporine blood levels in renal transplant recipients

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12 December 2020

Potentiation of neurotoxic side effects by coadministration of imipenem to cyclosporine therapy in a kidney transplant recipient--synergism of side effects or drug interaction?

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12 December 2020

Ketoconazole inhibits cyclosporine metabolism in vivo in mice

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12 December 2020

Metabolism of cyclosporin A. III. Interaction of the macrolide antibiotic, erythromycin, using rabbit hepatocytes and microsomal fractions.

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12 December 2020

Blood cyclosporine pharmacokinetics in patients undergoing marrow transplantation. Influence of age, obesity, and hematocrit

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12 December 2020

Ketoconazole and cyclosporin

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12 December 2020

Erythromycin and cyclosporine

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12 December 2020

The effect of verapamil on antipyrine pharmacokinetics and metabolism in man.

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12 December 2020

Pharmacokinetic interactions of the macrolide antibiotics

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12 December 2020

Possible interaction of ciprofloxacin with cyclosporin A

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12 December 2020

Interaction of calcium blockers and cyclosporine

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12 December 2020

Oral administration of cyclosporin A for recipients of allogeneic marrow transplants: implications of clinical gut dysfunction

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12 December 2020

Multiple dose pharmacokinetics of ketoconazole and their effects on antipyrine kinetics in man

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12 December 2020

Short-term effects of calcium antagonists on hemodynamics and cyclosporine pharmacokinetics in heart-transplant and kidney-transplant patients

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12 December 2020

Immunosuppressive metabolites of cyclosporine in the blood of renal allograft recipients

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12 December 2020

Drug interaction between cyclosporin and phenytoin in allogeneic bone marrow transplantation

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12 December 2020

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12 December 2020

Metabolism of cyclosporine

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12 December 2020

Interaction of erythromycin with cyclosporine

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12 December 2020

Absence of interaction between cyclosporine and spiramycin

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12 December 2020

Monitoring cyclosporin concentrations in marrow transplant recipients: comparison of two assay methods

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12 December 2020

Cyclosporine-cimetidine interaction

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12 December 2020

Verapamil inhibits cyclosporin metabolism

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12 December 2020

Concomitant administration of cyclosporin and ketoconazole in renal transplant recipients

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12 December 2020

Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin

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12 December 2020

The ketoconazole-cyclosporin interaction in an elderly renal transplant patient

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12 December 2020

Dosage of Cyclosporin A in children with renal transplants

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12 December 2020

Effects of erythromycin on gastrointestinal tract motility.

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12 December 2020

Interaction of cyclosporin and calcium antagonists

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12 December 2020

The effect of ketoconazole on hepatic oxidative drug metabolism in the rat in vivo and in vitro

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12 December 2020

Cyclosporine interactions with metronidazole and cimetidine

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12 December 2020

Measurement of cyclosporine and 18 metabolites in blood, bile, and urine by high-performance liquid chromatography

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12 December 2020

Confirmation of the interaction between cyclosporine and the calcium channel blocker nicardipine in renal transplant patients

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12 December 2020

Clinical pharmacokinetics of cyclosporin

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12 December 2020

High dose methylprednisolone increases plasma cyclosporin levels in renal transplant recipients

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12 December 2020

Interaction of cyclosporin and itraconazole

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12 December 2020

The effects and side effects of cyclosporine: relationship to drug pharmacokinetics

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12 December 2020

Intestinal lymphatic absorption of cyclosporin A following oral administration in an olive oil solution in rats

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12 December 2020

Measurement of blood cyclosporine metabolite concentrations with a new column-switching high-performance liquid chromatographic assay

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12 December 2020

Cyclosporin-phenytoin interaction: re-evaluation using metabolite data

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12 December 2020

Concomitant immunosuppressive and antibiotic therapy--reduction of cyclosporine A blood levels due to treatment with imipenem/cilastatin

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12 December 2020

Effect of erythromycin on blood cyclosporine concentrations in kidney transplant patients

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12 December 2020

Interaction of fluconazole with cyclosporin

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12 December 2020

Valproate for epilepsy in renal transplant recipients receiving cyclosporine

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12 December 2020

Norfloxacin and cyclosporine--a safe combination

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12 December 2020

Cyclosporine-phenytoin interaction

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12 December 2020

Renal cyclosporine clearance in marrow transplant recipients: age-related variation

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12 December 2020

Synergistic nephrotoxicity due to ciprofloxacin and cyclosporine

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12 December 2020

Interaction between cyclosporin A and phenobarbitone

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12 December 2020

Interaction between cyclosporin and rifampicin

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12 December 2020

Absorption of cyclosporine A after oral dosing

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12 December 2020

Inhibition and induction of microsomal enzymes in rat. A comparative study of four antimycotics: miconazole, econazole, clotrimazole and ketoconazole

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12 December 2020

Cyclosporin-verapamil interaction

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12 December 2020

Clinical Implications of Enzyme Induction and Enzyme Inhibition

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12 December 2020

The effect of phenobarbital and methylprednisolone on the biotransformation of cyclosporine in the rat

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12 December 2020

The cyclosporine-sparing effects of diltiazem in renal transplantation

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12 December 2020

Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver

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12 December 2020

Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites

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12 December 2020

Cyclosporine--high-dose steroid interaction in renal transplant recipients: assessment by HPLC

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12 December 2020

Ofloxacin in the treatment of urinary tract infection in renal transplant recipients

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12 December 2020

The effect of oral metoclopramide on the absorption of cyclosporine

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12 December 2020

Subtherapeutic cyclosporine concentrations during nafcillin therapy

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12 December 2020

Critical issues in cyclosporine monitoring: report of the Task Force on Cyclosporine Monitoring

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12 December 2020

Prevention of posttransplant acute tubular necrosis by the calcium antagonist diltiazem: a prospective randomized study

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12 December 2020

Isolation of 10 cyclosporine metabolites from human bile

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12 December 2020

Nephrotoxicity of trimethoprim and cotrimoxazole in renal allograft recipients treated with cyclosporine

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12 December 2020

Correlation of serum cyclosporine concentration with renal dysfunction in marrow transplant recipients

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12 December 2020

Ketoconazole does not impair antipyrine clearance in humans

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12 December 2020

Cyclosporin-diltiazem interaction

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12 December 2020

Lack of effect of spiramycin on cyclosporin pharmacokinetics

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12 December 2020

Nicardipine increases cyclosporin blood levels

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12 December 2020

In vitro immunosuppressive properties of cyclosporine metabolites

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12 December 2020

Erythromycin and cyclosporine

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12 December 2020

Interaction between erythromycin and cyclosporine in a kidney and pancreas allograft recipient

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12 December 2020

Cyclosporine metabolism in human liver: identification of a cytochrome P-450III gene family as the major cyclosporine-metabolizing enzyme explains interactions of cyclosporine with other drugs.

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12 December 2020

Rapid metabolism of cyclosporin and prednisone in kidney transplant patients on tuberculostatic treatment

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12 December 2020

Interaction of miconazole, ketoconazole and itraconazole with rat-liver microsomes

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12 December 2020

Changes in antipyrine and indocyanine green kinetics during nifedipine, verapamil, and diltiazem therapy

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12 December 2020

Interaction of fluconazole and cyclosporine

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12 December 2020

Concomitant administration of cyclosporine and ketoconazole for three and a half years in one heart transplant recipient

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12 December 2020

Exacerbation of cyclosporine toxicity by concomitant administration of erythromycin.

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12 December 2020

Patients receiving quinolones and cyclosporine after heart transplantation

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12 December 2020

Spiramycin does not increase plasma cyclosporin concentrations in renal transplant patients

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12 December 2020

Influence of nicardipine on renal function and plasma cyclosporin in renal transplant patients

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12 December 2020

Biotransformation and distribution in blood of cyclosporine and its metabolites

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12 December 2020

Erythromycin-cyclosporine interaction in renal transplant recipients

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12 December 2020

ORAL CONTRACEPTIVE INTERACTION WITH CYCLOSPORIN

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12 December 2020

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

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12 December 2020

Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation

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12 December 2020

Ranitidine and the cyclosporine-treated recipient

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12 December 2020

Calcium channel blockers and cyclosporine metabolism.

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12 December 2020

10.2165/00003088-199019050-00004

Identifiers

DOI

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PubMed ID

2268987

Dimensions Publication ID

27 August 2017

0 references

1 reference

PubMed ID

2268987