(Q35759276)

10 August 2017

Genome neighborhood network reveals insights into enediyne biosynthesis and facilitates prediction and prioritization for discovery (English)

1 reference

10 August 2017

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Xiaohui Yan

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Ben Shen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

1 reference

29 August 2015

1 reference

Journal of Industrial Microbiology & Biotechnology

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

2-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

261-276

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 June 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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2 October 2017

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Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19

2 October 2017

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2 October 2017

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2 October 2017

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Structures and comparative characterization of biosynthetic gene clusters for cyanosporasides, enediyne-derived natural products from marine actinomycetes

2 October 2017

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Cloning and sequencing of the kedarcidin biosynthetic gene cluster from Streptoalloteichus sp. ATCC 53650 revealing new insights into biosynthesis of the enediyne family of antitumor antibiotics.

2 October 2017

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Inference of functional properties from large-scale analysis of enzyme superfamilies

2 October 2017

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Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes

2 October 2017

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Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis

2 October 2017

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Complexity and simplicity in the biosynthesis of enediyne natural products

2 October 2017

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BLAST+: architecture and applications

2 October 2017

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Characterization of the SgcF epoxide hydrolase supporting an (R)-vicinal diol intermediate for enediyne antitumor antibiotic C-1027 biosynthesis

2 October 2017

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Characterization of SgcE6, the flavin reductase component supporting FAD-dependent halogenation and hydroxylation in the biosynthesis of the enediyne antitumor antibiotic C-1027

2 October 2017

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Total synthesis and structure revision of the (-)-maduropeptin chromophore

2 October 2017

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Potent antibody drug conjugates for cancer therapy

2 October 2017

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Biosynthesis of enediyne antitumor antibiotics

2 October 2017

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The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710

2 October 2017

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A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

2 October 2017

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Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses

2 October 2017

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Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis

2 October 2017

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Targeted cancer therapy: conferring specificity to cytotoxic drugs

2 October 2017

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Kedarcidin chromophore: synthesis of its proposed structure and evidence for a stereochemical revision

2 October 2017

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Cyanosporasides A and B, chloro- and cyano-cyclopenta[a]indene glycosides from the marine actinomycete "Salinispora pacifica".

2 October 2017

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The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases

2 October 2017

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Antitumor antibiotics: bleomycin, enediynes, and mitomycin

2 October 2017

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Antibody-targeted chemotherapy with the calicheamicin conjugate hu3S193-N-acetyl gamma calicheamicin dimethyl hydrazide targets Lewisy and eliminates Lewisy-positive human carcinoma cells and xenografts

2 October 2017

1 reference

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Cytoscape: a software environment for integrated models of biomolecular interaction networks

2 October 2017

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Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model

2 October 2017

1 reference

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Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1).

2 October 2017

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The calicheamicin gene cluster and its iterative type I enediyne PKS

2 October 2017

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Understanding and exploiting nature's chemical arsenal: the past, present and future of calicheamicin research.

2 October 2017

1 reference

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Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

Synthesis of (+)-dynemicin A and analogs of wide structural variability: establishment of the absolute configuration of natural dynemicin A.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

Improved sensitivity of profile searches through the use of sequence weights and gap excision.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

Mechanism of action of a new macromolecular antitumor antibiotic, C-1027.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

Unraveling the biosynthesis of the sporolide cyclohexenone building block.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

Sporolides A and B: structurally unprecedented halogenated macrolides from the marine actinomycete Salinispora tropica.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

The first total synthesis of N1999-A2: absolute stereochemistry and stereochemical implications into DNA cleavage

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4753101

p-Benzyne. Generation as an intermediate in a thermal isomerization reaction and trapping evidence for the 1,4-benzenediyl structure

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS10295-015-1671-0

A Unique cis-3-Hydroxy-l-proline Dehydratase in the Enolase Superfamily

21 January 2018

1 reference

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https://api.crossref.org/works/10.1007%2FS10295-015-1671-0

Sequence-specific double-strand breakage of DNA by neocarzinostatin involves different chemical mechanisms within a staggered cleavage site

21 January 2018

1 reference

12 December 2020

C-1027 enediyne chromophore: presence of another active form and its chemical structure

1 reference

12 December 2020

Characterization of a carbonyl-conjugated polyene precursor in 10-membered enediyne biosynthesis

1 reference

12 December 2020

Biosynthesis of the enediyne antitumor antibiotic C-1027

1 reference

12 December 2020

A new macromolecular antitumor antibiotic, C-1027. III. Antitumor activity

1 reference

12 December 2020

Uncialamycin, A New Enediyne Antibiotic

1 reference

12 December 2020

10.1007/S10295-015-1671-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26318027%20AND%20SRC:MED&resulttype=core&format=json