(Q35759964)

10 August 2017

title

Mimicking dominant negative inhibition of prion replication through structure-based drug design (English)

1 reference

10 August 2017

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5

S B Prusiner

1 reference

10 August 2017

6

F E Cohen

1 reference

10 August 2017

V Perrier

1

1 reference

10 August 2017

A C Wallace

series ordinal

2

1 reference

10 August 2017

K Kaneko

series ordinal

3

1 reference

10 August 2017

J Safar

series ordinal

4

1 reference

10 August 2017

language of work or name

English

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publication date

1 May 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

number of pages

6

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based on heuristic

inferred from page(s)

published in

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10 August 2017

volume

97

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10 August 2017

issue

11

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10 August 2017

page(s)

6073-6078

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Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Elimination of prions by branched polyamines and implications for therapeutics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Solution structure of Syrian hamster prion protein rPrP(90-231).

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Eight prion strains have PrP(Sc) molecules with different conformations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Anatomy of hot spots in protein interfaces

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

The anti-prion activity of Congo red. Putative mechanism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: a new homology modeling tool

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Chemical chaperones interfere with the formation of scrapie prion protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Transmission dynamics and epidemiology of BSE in British cattle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

A new variant of Creutzfeldt-Jakob disease in the UK.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Attempts to restore scrapie prion infectivity after exposure to protein denaturants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Mice devoid of PrP are resistant to scrapie

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Congo red prolongs the incubation period in scrapie-infected hamsters.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Structural clues to prion replication

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

A hot spot of binding energy in a hormone-receptor interface

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Novel proteinaceous infectious particles cause scrapie

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Probing Immunosuppressant Action with a Nonnatural Immunophilin Ligand

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Chimeric prion protein expression in cultured cells and transgenic mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Prion research: the next frontiers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Prion diseases and the BSE crisis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Characterization of scrapie infection in mouse neuroblastoma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Protein docking and complementarity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

An Algorithm for Subgraph Isomorphism

12 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Structural aspects of Congo red as an inhibitor of protease-resistant prion protein formation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Molecular analysis of the interaction of calcineurin with drug-immunophilin complexes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18560

Estimation of the number of people incubating variant CJD

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Predicting the CJD epidemic in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Deaths from variant Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Reversion of prion protein conformational changes by synthetic b-sheet breaker peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Human prion diseases with variant prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Association between natural scrapie and PrP genotype in a flock of Suffolk sheep in Scotland

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

Protective prion protein polymorphisms against sporadic Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

DBMAKER: a set of programs to generate three-dimensional databases based upon user-specified criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.97.11.6073

21 January 2018

Identifiers

DOI

10.1073/PNAS.97.11.6073

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference