(Q35760837)

10 August 2017

title

TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J. (English)

1 reference

10 August 2017

Xiaoyu Hu

4

0 references

author name string

Baohong Zhao

1

1 reference

10 August 2017

Shannon N Grimes

2

1 reference

10 August 2017

Susan Li

3

1 reference

10 August 2017

Lionel B Ivashkiv

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

16 January 2012

1 reference

Journal of Experimental Medicine

10 August 2017

published in

1 reference

10 August 2017

volume

209

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10 August 2017

issue

2

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10 August 2017

page(s)

319-334

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Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors

10 August 2017

cites work

1 reference

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2 October 2017

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Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss

2 October 2017

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2 October 2017

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Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent

2 October 2017

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Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

2 October 2017

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The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.

2 October 2017

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Blimp1-mediated repression of negative regulators is required for osteoclast differentiation

2 October 2017

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Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

2 October 2017

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Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

2 October 2017

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NF-kappaB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism

2 October 2017

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Targeting TNF for Treatment of Cancer and Autoimmunity

2 October 2017

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Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

2 October 2017

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2 October 2017

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The canonical Notch signaling pathway: unfolding the activation mechanism

2 October 2017

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NF-kappaB serves as a cellular sensor of Kaposi's sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator.

2 October 2017

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Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways

2 October 2017

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Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells.

2 October 2017

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The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis

2 October 2017

1 reference

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Notch inhibits osteoblast differentiation and causes osteopenia

2 October 2017

1 reference

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RelB is the NF-kappaB subunit downstream of NIK responsible for osteoclast differentiation

2 October 2017

1 reference

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Dimorphic effects of Notch signaling in bone homeostasis.

2 October 2017

1 reference

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Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

2 October 2017

1 reference

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The osteoclast: friend or foe?

2 October 2017

1 reference

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Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.

2 October 2017

1 reference

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Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systems

2 October 2017

1 reference

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Notch signalling regulates stem cell numbers in vitro and in vivo

2 October 2017

1 reference

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Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease

2 October 2017

1 reference

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Osteoclasts; culprits in inflammatory osteolysis

2 October 2017

1 reference

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PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L.

2 October 2017

1 reference

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Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation

2 October 2017

1 reference

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M-CSF mediates TNF-induced inflammatory osteolysis

2 October 2017

1 reference

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Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis

2 October 2017

1 reference

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Regulation of lymphoid development, differentiation, and function by the Notch pathway.

2 October 2017

1 reference

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Viral interactions with the Notch pathway

2 October 2017

1 reference

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Notch signaling controls multiple steps of pancreatic differentiation

2 October 2017

1 reference

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Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Factor recruitment and TIF2/GRIP1 corepressor activity at a collagenase-3 response element that mediates regulation by phorbol esters and hormones

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

The TNF and TNF receptor superfamilies: integrating mammalian biology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Disruption of the mouse RBP-J kappa gene results in early embryonic death

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Induction of arthritis with monoclonal antibodies to collagen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Tumor necrosis factor-alpha increases circulating osteoclast precursor numbers by promoting their proliferation and differentiation in the bone marrow through up-regulation of c-Fms expression.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3280875

Osteoclasts and arthritis

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20111566

Suppression of the effector phase of inflammatory arthritis by double-stranded RNA is mediated by type I IFNs

21 January 2018

1 reference

12 December 2020

MafB negatively regulates RANKL-mediated osteoclast differentiation

1 reference

12 December 2020

Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts

1 reference

12 December 2020

Sensitization of IFN-γ Jak-STAT signaling during macrophage activation

1 reference

12 December 2020

The JAK/STAT pathway in rheumatoid arthritis: Pathogenic or protective?

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20111566

1 reference

10 August 2017

1 reference

10 August 2017

1 reference