(Q35762785)

10 August 2017

title

Challenges and opportunities of defining clinical leptin resistance (English)

1 reference

10 August 2017

8

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10 August 2017

7

Matthias H Tschöp

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10 August 2017

2

Steven B Heymsfield

1 reference

10 August 2017

6

Rudolph L Leibel

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10 August 2017

4

Barbara B Kahn

1 reference

10 August 2017

Martin G Myers

1

1 reference

10 August 2017

Carol Haft

series ordinal

3

1 reference

10 August 2017

Maren Laughlin

series ordinal

5

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10 August 2017

publication date

1 February 2012

1 reference

10 August 2017

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10 August 2017

volume

15

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10 August 2017

issue

2

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10 August 2017

page(s)

150-156

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Molecular mapping of mouse brain regions innervated by leptin receptor-expressing cells

10 August 2017

cites work

1 reference

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2 October 2017

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Obesity and leptin resistance: distinguishing cause from effect

2 October 2017

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Reduced body weight and increased energy expenditure in transgenic mice over-expressing soluble leptin receptor

2 October 2017

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Hyperleptinemia is required for the development of leptin resistance

2 October 2017

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Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels

2 October 2017

1 reference

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Leptin deficiency causes insulin resistance induced by uncontrolled diabetes

2 October 2017

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2 October 2017

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2 October 2017

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The soluble leptin receptor neutralizes leptin-mediated STAT3 signalling and anorexic responses in vivo

2 October 2017

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Leptin targets in the mouse brain

2 October 2017

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Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice

2 October 2017

1 reference

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The geometry of leptin action in the brain: more complicated than a simple ARC.

2 October 2017

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2 October 2017

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Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

2 October 2017

1 reference

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Molecular and neural mediators of leptin action

2 October 2017

1 reference

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Central nervous system neuropeptide Y signaling modulates VLDL triglyceride secretion.

2 October 2017

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Hypothalamic pathways linking energy balance and reproduction

2 October 2017

1 reference

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The central melanocortin system directly controls peripheral lipid metabolism

2 October 2017

1 reference

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Metabolic syndrome and adipose tissue: new clinical aspects and therapeutic targets

2 October 2017

1 reference

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Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function

2 October 2017

1 reference

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Interactions between the "cognitive" and "metabolic" brain in the control of food intake

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Regulation of body mass and adiposity in the field vole, Microtus agrestis: a model of leptin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Endocrine assessment, molecular characterization and treatment of growth hormone insensitivity disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Recombinant human leptin in women with hypothalamic amenorrhea.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Rapid rewiring of arcuate nucleus feeding circuits by leptin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Trophic action of leptin on hypothalamic neurons that regulate feeding

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

PTP1B regulates leptin signal transduction in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Selective deletion of leptin receptor in neurons leads to obesity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Transcriptional profiling reveals global defects in energy metabolism, lipoprotein, and bile acid synthesis and transport with reversal by leptin treatment in ob/ob mouse liver

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Obesity and the regulation of energy balance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Transgenic mice overexpressing leptin accumulate adipose mass at an older, but not younger, age.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

The role of SOCS-3 in leptin signaling and leptin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Effects of recombinant leptin therapy in a child with congenital leptin deficiency.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Identification of SOCS-3 as a potential mediator of central leptin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Distributions of leptin receptor mRNA isoforms in the rat brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Leptin rapidly suppresses insulin release from insulinoma cells, rat and human islets and, in vivo, in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Role of leptin in the neuroendocrine response to fasting

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Identification and expression cloning of a leptin receptor, OB-R

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Positional cloning of the mouse obese gene and its human homologue

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Insulin resistance--mechanisms, syndromes, and implications

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Spontaneous caloric restriction associated with increased leptin levels in obesity-resistant αMUPA mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Mechanisms of amylin/leptin synergy in rodent models

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Endoplasmic reticulum stress plays a central role in development of leptin resistance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Developmental programming of the hypothalamus: a matter of fat.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Central leptin acutely reverses diet-induced hepatic insulin resistance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Leptin-replacement therapy for lipodystrophy.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281561

Editorial: leptin as a therapeutic agent--trials and tribulations

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22326217

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential accessibility of circulating leptin to individual hypothalamic sites

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22326217

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2012.01.002

1 reference

10 August 2017

1 reference

10 August 2017

1 reference