(Q35764234)

10 August 2017

title

Tau stabilizes microtubules by binding at the interface between tubulin heterodimers (English)

1 reference

10 August 2017

8

Markus Zweckstetter

0 references

Eckhard Mandelkow

7

object named as

Eckhard Mandelkow

1 reference

10 August 2017

6

Henning Urlaub

1 reference

10 August 2017

author name string

Harindranath Kadavath

1

1 reference

10 August 2017

Romina V Hofele

2

1 reference

10 August 2017

Jacek Biernat

3

1 reference

10 August 2017

Satish Kumar

4

1 reference

10 August 2017

Katharina Tepper

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 June 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

1 reference

10 August 2017

volume

112

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10 August 2017

issue

24

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10 August 2017

page(s)

7501-7506

1 reference

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

10 August 2017

cites work

1 reference

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Microtubule stabilizing agents as potential treatment for Alzheimer's disease and related neurodegenerative tauopathies

2 October 2017

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What tubulin drugs tell us about microtubule structure and dynamics

2 October 2017

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Systematic identification of tubulin-interacting fragments of the microtubule-associated protein Tau leads to a highly efficient promoter of microtubule assembly

2 October 2017

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Database search algorithm for identification of intact cross-links in proteins and peptides using tandem mass spectrometry.

2 October 2017

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2 October 2017

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2 October 2017

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Structural polymorphism of 441-residue tau at single residue resolution

2 October 2017

1 reference

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Structural insight into the inhibition of tubulin by vinca domain peptide ligands

2 October 2017

1 reference

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Identification and characterization of disulfide bonds in proteins and peptides from tandem MS data by use of the MassMatrix MS/MS search engine

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

In-gel digestion for mass spectrometric characterization of proteins and proteomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

N-terminal stathmin-like peptides bind tubulin and impede microtubule assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Molecular motors and mechanisms of directional transport in neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Surface-decoration of microtubules by human tau

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Evidence for two distinct binding sites for tau on microtubules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Repeat motifs of tau bind to the insides of microtubules in the absence of taxol

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Refined structure of alpha beta-tubulin at 3.5 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Going new places using an old MAP: tau, microtubules and human neurodegenerative disease.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Polarization transfer by cross-correlated relaxation in solution NMR with very large molecules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Structure of the alpha beta tubulin dimer by electron crystallography

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Attenuated T2 relaxation by mutual cancellation of dipole-dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Microtubules and microtubule-associated proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Beyond self-assembly: from microtubules to morphogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Tau protein function in living cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Developmentally regulated expression of specific tau sequences

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Structural characterization of the core of the paired helical filament of Alzheimer disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Molecular cloning of a ubiquitously distributed microtubule-associated protein with Mr 190,000.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Tau protein binds to microtubules through a flexible array of distributed weak sites

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

A protein factor essential for microtubule assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Conservation of microtubule associated proteins. Isolation and characterization of tau and the high molecular weight microtubule associated protein from chicken brain and from mouse fibroblasts and comparison to the corresponding mammalian brain pro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Physical and chemical properties of purified tau factor and the role of tau in microtubule assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Insights into the activation of the helicase Prp43 by biochemical studies and structural mass spectrometry

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Tubulin domains probed by limited proteolysis and subunit-specific antibodies.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Localization of the tubulin binding site for tau protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

The "jaws" of the tau-microtubule interaction.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Structural basis for the regulation of tubulin by vinblastine

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Two photoaffinity analogues of the tripeptide, hemiasterlin, exclusively label alpha-tubulin

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Isotope-tagged cross-linking reagents. A new tool in mass spectrometric protein interaction analysis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Kinetic stabilization of microtubule dynamics at steady state by tau and microtubule-binding domains of tau.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4475932

Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1504081112

Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1504081112

The dynamic structure of filamentous tau

21 January 2018

1 reference

12 December 2020

Characterization of Ligand Binding by Saturation Transfer Difference NMR Spectroscopy

1 reference

12 December 2020

Domains of tau protein and interactions with microtubules

1 reference

12 December 2020

Taxol-induced flexibility of microtubules and its reversal by MAP-2 and Tau

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1504081112

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference