(Q35773980)

English

Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.

scientific article published on 22 December 2011

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19 January 2020

Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3 (English)

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19 January 2020

Liliana Schaefer

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19 January 2020

Renato V. Iozzo

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Thomas Neill

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Simone Buraschi

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Rick T Owens

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Michael P Lisanti

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19 January 2020

Journal of Biological Chemistry

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19 January 2020

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Matrix proteoglycans: from molecular design to cellular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Expression of small extracellular chondroitin/dermatan sulfate proteoglycans is differentially regulated in human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Proteoglycans of the extracellular environment: clues from the gene and protein side offer novel perspectives in molecular diversity and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Abnormal expression of perlecan proteoglycan in metastatic melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Perlecan: a gem of a proteoglycan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Scatter factor induces blood vessel formation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Proteoglycan changes in the intercellular matrix of human colon carcinoma: an integrated biochemical and stereologic analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

12 July 2018

Collagen fibril organization in the pregnant endometrium of decorin-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Alterations in lung mechanics in decorin-deficient mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

A role for decorin in cutaneous wound healing and angiogenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

A central role for decorin during vertebrate convergent extension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Extracellular matrix proteoglycans control the fate of bone marrow stromal cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

A role for decorin in the remodeling of myocardial infarction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Ectopic decorin expression up-regulates VEGF expression in mouse cerebral endothelial cells via activation of the transcription factors Sp1, HIF1alpha, and Stat3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Assessment of gelatinase expression and activity in articular cartilage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

25 September 2018

Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3285326

25 September 2018

A positive feedback loop between hepatocyte growth factor receptor and β-catenin sustains colorectal cancer cell invasive growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283499

21 January 2018

Investigating Tendon Fascicle Structure–Function Relationships in a Transgenic-Age Mouse Model Using Multiple Regression Models

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin-induced Growth Suppression Is Associated with Up-regulation of p21, an Inhibitor of Cyclin-dependent Kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin Activates the Epidermal Growth Factor Receptor and Elevates Cytosolic Ca2+in A431 Carcinoma Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of Decorin and Biglycan on Mechanical Properties of Multiple Tendons in Knockout Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrovirally mediated expression of decorin by macrovascular endothelial cells. Effects on cellular migration and fibronectin fibrillogenesis in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Anti-oncogenic Role for Decorin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin inhibits endothelial migration and tube-like structure formation: role of thrombospondin-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decorin suppresses tumor cell-mediated angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194599

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.283499

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22194599%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22194599%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22194599%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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