(Q35776733)

10 August 2017

title

Protein kinase C regulation of 12-lipoxygenase-mediated human platelet activation (English)

1 reference

10 August 2017

Victor Kenyon

4

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Ajit Jadhav

object named as

Ajit Jadhav

6

0 references

Anton Simeonov

7

object named as

Anton Simeonov

1 reference

10 August 2017

10

Olivier Boutaud

1 reference

10 August 2017

Jennifer Yeung

1

1 reference

10 August 2017

Patrick L Apopa

2

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10 August 2017

Joanne Vesci

3

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10 August 2017

Ganesha Rai

5

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10 August 2017

Theodore R Holman

8

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10 August 2017

David J Maloney

9

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10 August 2017

Michael Holinstat

11

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10 August 2017

publication date

9 December 2011

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10 August 2017

published in

Molecular Pharmacology

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10 August 2017

volume

81

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10 August 2017

issue

3

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10 August 2017

page(s)

420-430

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Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase

10 August 2017

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1 reference

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Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+.

12 July 2018

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Functional characterization of mutations in inherited human cPLA₂ deficiency

12 July 2018

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Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis

12 July 2018

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Genotyping: one piece of the puzzle to personalize antiplatelet therapy

12 July 2018

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Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation

12 July 2018

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12 July 2018

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Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.

12 July 2018

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Protein kinase Calpha: disease regulator and therapeutic target.

12 July 2018

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Protein kinase C[delta] differentially regulates platelet functional responses

12 July 2018

1 reference

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PKCalpha regulates platelet granule secretion and thrombus formation in mice

12 July 2018

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Lipoxygenase metabolism: roles in tumor progression and survival

12 July 2018

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Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases.

12 July 2018

1 reference

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Low-dose aspirin for the prevention of atherothrombosis

12 July 2018

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12 July 2018

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Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial

12 July 2018

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Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry

12 July 2018

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Platelet ERK2 activation by thrombin is dependent on calcium and conventional protein kinases C but not Raf-1 or B-Raf

12 July 2018

1 reference

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12-lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation

12 July 2018

1 reference

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Regulation of c-fos induction in lens epithelial cells by 12(S)HETE-dependent activation of PKC.

12 July 2018

1 reference

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Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells

12 July 2018

1 reference

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Anti-thrombotic and anticoagulant treatment in interventional cardiology

12 July 2018

1 reference

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12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-alpha in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids

12 July 2018

1 reference

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A review of possible roles of the platelet 12-lipoxygenase

12 July 2018

1 reference

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Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release

12 July 2018

1 reference

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Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets.

12 July 2018

1 reference

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PKC inhibitors RO 31-8220 and Gö 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation

25 September 2018

1 reference

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Platelet lipoxygenase inhibitors attenuate thrombin- and thromboxane mimetic-induced intracellular calcium mobilization and platelet aggregation

25 September 2018

1 reference

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Inhibition of mitogen-activated protein kinase kinase does not impair primary activation of human platelets

25 September 2018

1 reference

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Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKC-mediated serine phosphorylation events in melanoma cells

25 September 2018

1 reference

12 December 2020

Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid

1 reference

12 December 2020

A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca2+-Dependent Protein Kinase

1 reference

12 December 2020

Selective activation of the gamma-subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

1 reference

12 December 2020

Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets

1 reference

12 December 2020

Protein kinase C activation without membrane contact in platelets stimulated by bryostatin

1 reference

12 December 2020

Activation of myelin basic protein and S6 peptide kinases in phorbol ester- and PAF-treated sheep platelets

1 reference

12 December 2020

Regulation of c-jun-NH2 terminal kinase and extracellular-signal regulated kinase in human platelets

1 reference

12 December 2020

Essential role of protein kinase C delta in platelet signaling, alpha IIb beta 3 activation, and thromboxane A2 release

1 reference

12 December 2020

Dual role of platelet protein kinase C in thrombus formation: stimulation of pro-aggregatory and suppression of procoagulant activity in platelets

1 reference

12 December 2020

12-lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway

1 reference

12 December 2020

Thrombin induces activation of p38 MAP kinase in human platelets

1 reference

12 December 2020

Identifiers

DOI

10.1124/MOL.111.075630

1 reference

10 August 2017

1 reference

10 August 2017

1 reference