(Q35784506)

10 August 2017

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title

The mRNA cap-binding protein eIF4E in post-transcriptional gene expression (English)

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10 August 2017

Tobias von der Haar

1

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10 August 2017

John D Gross

series ordinal

2

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10 August 2017

Gerhard Wagner

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3

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10 August 2017

John E G McCarthy

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4

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10 August 2017

1 June 2004

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Nature Structural & Molecular Biology

10 August 2017

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10 August 2017

11

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10 August 2017

503-511

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10 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/nsmb779

10 August 2017

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cites work

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The scanning model for translation: an update

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Selective killing of cancer cells based on translational control of a suicide gene.

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Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?

31 March 2020

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Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP

31 March 2020

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Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

31 March 2020

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Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein

31 March 2020

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Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

31 March 2020

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Structural Features of Human Initiation Factor 4E, Studied by X-ray Crystal Analyses and Molecular Dynamics Simulations

31 March 2020

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Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

31 March 2020

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Nucleotide pools of growing, synchronized and stressed cultures of Saccharomyces cerevisiae

31 March 2020

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Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap-complex function

31 March 2020

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DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway

31 March 2020

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Internal and overall motions of the translation factor eIF4E: cap binding and insertion in a CHAPS detergent micelle

31 March 2020

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Mutations in the S4-H2 loop of eIF4E which increase the affinity for m7GTP.

31 March 2020

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Binding of protein synthesis initiation factor 4E to oligoribonucleotides: effects of cap accessibility and secondary structure

31 March 2020

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Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5'-Cap by domains of eIF4G.

31 March 2020

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PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

31 March 2020

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Regulation of human eIF4E by 4E-BP1: binding analysis using surface plasmon resonance

31 March 2020

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Fluorescence studies on association of human translation initiation factor eIF4E with mRNA cap-analogues

31 March 2020

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Interaction of wheat germ protein synthesis initiation factor eIF-(iso)4F and its subunits p28 and p86 with m7GTP and mRNA analogues

31 March 2020

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Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor eIF-4E: increased cap affinity of the phosphorylated form

31 March 2020

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A second eIF4E protein in Schizosaccharomyces pombe has distinct eIF4G-binding properties.

31 March 2020

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Repressor binding to a dorsal regulatory site traps human eIF4E in a high cap-affinity state

31 March 2020

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Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA.

31 March 2020

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Stopped-flow and Brownian dynamics studies of electrostatic effects in the kinetics of binding of 7-methyl-GpppG to the protein eIF4E

31 March 2020

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Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5' cap in yeast involves a site partially shared by p20.

31 March 2020

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The Cap-binding protein eIF4E promotes folding of a functional domain of yeast translation initiation factor eIF4G1.

31 March 2020

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A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery

31 March 2020

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RNA-binding activity of translation initiation factor eIF4G1 from Saccharomyces cerevisiae

31 March 2020

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The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein

31 March 2020

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Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation

31 March 2020

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Cup is an eIF4E binding protein required for both the translational repression of oskar and the recruitment of Barentsz

31 March 2020

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Bicoid associates with the 5'-cap-bound complex of caudal mRNA and represses translation

31 March 2020

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The proline-rich homeodomain protein, PRH, is a tissue-specific inhibitor of eIF4E-dependent cyclin D1 mRNA transport and growth

31 March 2020

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A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E.

31 March 2020

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The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E.

31 March 2020

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eIF4G dramatically enhances the binding of eIF4E to the mRNA 5'-cap structure

31 March 2020

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Wheat germ poly(A) binding protein enhances the binding affinity of eukaryotic initiation factor 4F and (iso)4F for cap analogues.

31 March 2020

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Homeostasis in mRNA initiation: wheat germ poly(A)-binding protein lowers the activation energy barrier to initiation complex formation

31 March 2020

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Biochemical characterisation of cap-poly(A) synergy in rabbit reticulocyte lysates: the eIF4G-PABP interaction increases the functional affinity of eIF4E for the capped mRNA 5'-end

31 March 2020

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Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein

31 March 2020

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eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

31 March 2020

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Translational regulation in cell stress and apoptosis. Roles of the eIF4E binding proteins

31 March 2020

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A reevaluation of the cap-binding protein, eIF4E, as a rate-limiting factor for initiation of translation in reticulocyte lysate

31 March 2020

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Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

31 March 2020

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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

31 March 2020

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Analysis of the isoform of Xenopus euakryotic translation initiation factor 4E.

31 March 2020

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Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

31 March 2020

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Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis

31 March 2020

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The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5' secondary structure.

31 March 2020

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Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

31 March 2020

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The enzymes and control of eukaryotic mRNA turnover

31 March 2020

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The eukaryotic mRNA decapping protein Dcp1 interacts physically and functionally with the eIF4F translation initiation complex

31 March 2020

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Modulation of eukaryotic mRNA stability via the cap-binding translation complex eIF4F.

31 March 2020

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mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E.

31 March 2020

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Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast

31 March 2020

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mRNA stabilization by poly(A) binding protein is independent of poly(A) and requires translation.

31 March 2020

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The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes.

31 March 2020

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The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme

31 March 2020

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Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs

31 March 2020

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Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

31 March 2020

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eIF4E isoform 2 in Schizosaccharomyces pombe is a novel stress-response factor

31 March 2020

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Functional link between the mammalian exosome and mRNA decapping

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB779

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Dimensions Publication ID

10 August 2017

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