(Q35794590)

10 August 2017

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title

Apolipoprotein E dose-dependent modulation of beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease (English)

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10 August 2017

Ronald B DeMattos

1

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10 August 2017

1 January 2004

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Journal of Molecular Neuroscience

10 August 2017

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10 August 2017

23

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10 August 2017

3

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10 August 2017

255-262

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https://scigraph.springernature.com/pub.10.1385/jmn:23:3:255

10 August 2017

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cites work

Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats.

1 reference

12 December 2020

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

1 reference

12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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12 December 2020

Expression of apolipoprotein E during nerve degeneration and regeneration

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12 December 2020

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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12 December 2020

Hepatic expression of genes regulating lipid metabolism in rabbits

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12 December 2020

Neurodegeneration and cognitive impairment in apoE-deficient mice is ameliorated by infusion of recombinant apoE.

1 reference

12 December 2020

Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

1 reference

12 December 2020

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

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12 December 2020

Effect of apolipoprotein E on neurite outgrowth and beta-amyloid-induced toxicity in developing rat primary hippocampal cultures

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12 December 2020

Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia.

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12 December 2020

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

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12 December 2020

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

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12 December 2020

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition.

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12 December 2020

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

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12 December 2020

Alzheimer's disease: perspectives for the new millennium

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12 December 2020

Role of apolipoprotein E and estrogen in mossy fiber sprouting in hippocampal slice cultures

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12 December 2020

Blood-brain barrier transport of circulating Alzheimer's amyloid beta

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12 December 2020

Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro

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12 December 2020

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

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12 December 2020

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

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12 December 2020

Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.

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12 December 2020

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

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12 December 2020

Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta

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12 December 2020

Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries.

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12 December 2020

Apolipoprotein E: structure-function relationships

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12 December 2020

Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease.

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12 December 2020

Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth

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12 December 2020

Alzheimer's disease: a central role for amyloid

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12 December 2020

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

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12 December 2020

Apolipoprotein E in animal models of CNS injury and in Alzheimer's disease

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12 December 2020

Induction of rat E and chicken A-I apolipoproteins and mRNAs during optic nerve degeneration.

1 reference

12 December 2020

A minimally lipidated form of cell-derived apolipoprotein E exhibits isoform-specific stimulation of neurite outgrowth in the absence of exogenous lipids or lipoproteins

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12 December 2020

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

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12 December 2020

Isoform-specific effect of apolipoprotein E on cell survival and beta-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures.

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12 December 2020

Normal and abnormal biology of the beta-amyloid precursor protein

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12 December 2020

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

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12 December 2020

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

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12 December 2020

Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury.

1 reference

12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

The presence of apoE4, not the absence of apoE3, contributes to AD pathology

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12 December 2020

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

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12 December 2020

A test of the cytosolic apolipoprotein E hypothesis fails to detect the escape of apolipoprotein E from the endocytic pathway into the cytosol and shows that direct expression of apolipoprotein E in the cytosol is cytotoxic.

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12 December 2020

Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

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12 December 2020

Apolipoprotein E synthesis in peripheral tissues of nonhuman primates.

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12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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12 December 2020

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

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12 December 2020

Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3.

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12 December 2020

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

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12 December 2020

Quantitation of apolipoprotein E mRNA in the liver and peripheral tissues of nonhuman primates.

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12 December 2020

Apolipoprotein E epsilon 4 is associated with the presence and earlier onset of hemorrhage in cerebral amyloid angiopathy

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12 December 2020

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

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12 December 2020

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

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12 December 2020

Human and murine ApoE markedly alters A beta metabolism before and after plaque formation in a mouse model of Alzheimer's disease.

1 reference

12 December 2020

Potential role of apoE in structural plasticity in the nervous system; implications for disorders of the central nervous system

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12 December 2020

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

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12 December 2020

Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

1 reference

12 December 2020

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

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12 December 2020

Truncated apolipoprotein E (ApoE) causes increased intracellular calcium and may mediate ApoE neurotoxicity.

1 reference

12 December 2020

Alzheimer's disease: genotypes, phenotypes, and treatments

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12 December 2020

Isoform-specific binding of apolipoprotein E to beta-amyloid

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12 December 2020

Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy

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12 December 2020

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

12 December 2020

Identifiers

DOI

10.1385/JMN:23:3:255

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PubMed ID

15181254

Dimensions Publication ID

10 August 2017

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1 reference

PubMed ID

15181254