(Q48477194)

English

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.

scientific article published in May 1998

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/9547235

Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

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6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

David M. Holtzman

8

object named as

D M Holtzman

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

7

object named as

A M Fagan

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

author name string

Y Sun

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

S Wu

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

G Bu

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

M K Onifade

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

S N Patel

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 May 1998

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/9547235

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

3261-3272

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

Human APOE protein localized in brains of transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ApoE genotype and survival from intracerebral haemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human apolipoprotein E: the Alzheimer's disease connection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E binds to and potentiates the biological activity of ciliary neurotrophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: a central role for amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary structure of alpha 2-macroglobulin receptor-associated protein. Human homologue of a Heymann nephritis antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E, a gene with complex biological interactions in the aging brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Failed compensatory dendritic growth as a pathophysiological process in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific binding of apolipoprotein E to beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of gene expression in mouse trisomy 16, an animal model of Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low density lipoprotein receptor-related protein is expressed early and becomes restricted to a somatodendritic domain during neuronal differentiation in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of sprouting in the adult central nervous system: cellular responses in areas of terminal degeneration and reinnervation in the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of apolipoprotein E polymorphism with outcome after head injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytic apolipoprotein E mRNA and GFAP mRNA in hippocampus after entorhinal cortex lesioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific modulation by apolipoprotein E of the activities of secreted beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoproteins and their receptors in the central nervous system. Characterization of the lipoproteins in cerebrospinal fluid and identification of apolipoprotein B,E(LDL) receptors in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discovery of a brain promoter from the human transferrin gene and its utilization for development of transgenic mice that express human apolipoprotein E alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 39-kDa receptor-associated protein regulates ligand binding by the very low density lipoprotein receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nascent astrocyte particles differ from lipoproteins in CSF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TrkA expression in the CNS: evidence for the existence of several novel NGF-responsive CNS neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the very low-density lipoprotein receptor (VLDL-r), an apolipoprotein-E receptor, in the central nervous system and in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor-mediated endocytosis of tissue-type plasminogen activator by low density lipoprotein receptor-related protein on human hepatoma HepG2 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The low-density lipoprotein receptor-related protein, a multifunctional apolipoprotein E receptor, modulates hippocampal neurite development

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GFAP promoter directs astrocyte-specific expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP).

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration in the central nervous system of apoE-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous FGF-2 is important for cholinergic sprouting in the denervated hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: association with high density lipoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preliminary report of a genetic basis for cognitive decline after cardiac operations. The Neurologic Outcome Research Group of the Duke Heart Center.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted forms of beta-amyloid precursor protein modulate dendrite outgrowth and calcium responses to glutamate in cultured embryonic hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of apolipoprotein E mRNA in rat microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E gene expression in astrocytes: developmental pattern and regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and function of the low density lipoprotein receptor-related protein (LRP) in mammalian central neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E-deficient mice have increased susceptibility to focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoproteins in human cerebrospinal fluid

1 reference

https://pubmed.ncbi.nlm.nih.gov/9547235

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.18-09-03261.1998

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6792658&resulttype=core&format=json

12 May 2020

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