(Q35798161)

10 August 2017

title

Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T (English)

1 reference

10 August 2017

8

Alfred Ayala

1 reference

10 August 2017

7

Ronald P DeMatteo

1 reference

10 August 2017

Rachel A Burga

1

1 reference

10 August 2017

Mitchell Thorn

2

1 reference

10 August 2017

Gary R Point

3

1 reference

10 August 2017

Prajna Guha

4

1 reference

10 August 2017

Cang T Nguyen

5

1 reference

10 August 2017

Lauren A Licata

6

1 reference

10 August 2017

N Joseph Espat

9

1 reference

10 August 2017

Richard P Junghans

10

1 reference

10 August 2017

Steven C Katz

11

1 reference

10 August 2017

publication date

8 April 2015

1 reference

Cancer Immunology, Immunotherapy

10 August 2017

published in

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10 August 2017

volume

64

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10 August 2017

issue

7

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10 August 2017

page(s)

817-829

1 reference

describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4485571/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s00262-015-1692-6

0 references

cites work

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11 July 2018

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11 July 2018

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11 July 2018

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Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

11 July 2018

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11 July 2018

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11 July 2018

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Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

11 July 2018

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The liver is a site for tumor-induced myeloid-derived suppressor cell accumulation and immunosuppression

11 July 2018

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New paradigm in the management of liver-only metastases from colorectal cancer

11 July 2018

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Myeloid-derived suppressor cells as regulators of the immune system

11 July 2018

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Second-generation anti-carcinoembryonic antigen designer T cells resist activation-induced cell death, proliferate on tumor contact, secrete cytokines, and exhibit superior antitumor activity in vivo: a preclinical evaluation

11 July 2018

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Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

11 July 2018

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Actual 10-year survival after resection of colorectal liver metastases defines cure.

11 July 2018

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The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

11 July 2018

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Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion

11 July 2018

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Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway

11 July 2018

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Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression

11 July 2018

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High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells

11 July 2018

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GVAX (GMCSF gene modified tumor vaccine) in advanced stage non small cell lung cancer

11 July 2018

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L-arginine metabolism in myeloid cells controls T-lymphocyte functions.

11 July 2018

1 reference

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Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Expression of programmed death 1 ligands by murine T cells and APC

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Increased recurrence and metastasis in patients whose primary head and neck squamous cell carcinomas secreted granulocyte-macrophage colony-stimulating factor and contained CD34+ natural suppressor cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

CEA tissue staining in colorectal cancer patients. A way to improve the usefulness of serial serum CEA evaluation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

PD-L1 expression on tolerogenic APCs is controlled by STAT-3.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Overall survival of patients with advanced colorectal cancer correlates with availability of fluorouracil, irinotecan, and oxaliplatin regardless of whether doublet or single-agent therapy is used first line

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Liver sinusoidal endothelial cells are insufficient to activate T cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

In vivo activation of JAK2/STAT-3 pathway during angiogenesis induced by GM-CSF.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4485571

Conventional liver CD4 T cells are functionally distinct and suppressed by environmental factors

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00262-015-1692-6

T cell infiltrate predicts long-term survival following resection of colorectal cancer liver metastases

21 January 2018

1 reference

12 December 2020

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

12 December 2020

Recruitment of a myeloid cell subset (CD11b/Gr1mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis*

1 reference

12 December 2020

GM-CSF induces bone marrow precursors of NOD mice to skew into tolerogenic dendritic cells that protect against diabetes

1 reference

12 December 2020

10.1007/S00262-015-1692-6

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference