(Q35801045)

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Targeting Nrf2 by dihydro-CDDO-trifluoroethyl amide enhances autophagic clearance and viability of β-cells in a setting of oxidative stress

scientific article published on 8 May 2014

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Europe PubMed Central

PMC publication ID

10 August 2017

Targeting Nrf2 by dihydro-CDDO-trifluoroethyl amide enhances autophagic clearance and viability of β-cells in a setting of oxidative stress (English)

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10 August 2017

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13

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2 June 2020

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Wenjuan Li

1

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2 June 2020

Weiwei Wu

2

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2 June 2020

Haibo Song

3

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2 June 2020

Fang Wang

4

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2 June 2020

Huanjie Li

5

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2 June 2020

Li Chen

6

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2 June 2020

Yimu Lai

7

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2 June 2020

Joseph S Janicki

8

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2 June 2020

Keith W Ward

9

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2 June 2020

Colin J Meyer

10

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2 June 2020

Xing Li Wang

11

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2 June 2020

Dongqi Tang

12

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2 June 2020

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8 May 2014

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10 August 2017

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2 June 2020

588

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2 June 2020

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2 June 2020

2115-2124

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2 June 2020

The Keap1-Nrf2 system prevents onset of diabetes mellitus

1 reference

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11 July 2018

Tacrolimus inhibits the revascularization of isolated pancreatic islets

1 reference

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11 July 2018

New player on an old field; the keap1/Nrf2 pathway as a target for treatment of type 2 diabetes and metabolic syndrome

1 reference

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11 July 2018

Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage

1 reference

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11 July 2018

Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Integration of Clearance Mechanisms: The Proteasome and Autophagy

1 reference

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11 July 2018

Methods in mammalian autophagy research

1 reference

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11 July 2018

Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Targeting the Nrf2 pathway against cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Autophagy, redox signaling, and ventricular remodeling

1 reference

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11 July 2018

Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Triterpenoid CDDO-methyl ester inhibits the Janus-activated kinase-1 (JAK1)-->signal transducer and activator of transcription-3 (STAT3) pathway by direct inhibition of JAK1 and STAT3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Regulation of heme oxygenase-1 expression by demethoxy curcuminoids through Nrf2 by a PI3-kinase/Akt-mediated pathway in mouse beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

The roles of intracellular protein-degradation pathways in neurodegeneration

1 reference

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11 July 2018

Triterpenoid CDDO-Me blocks the NF-kappaB pathway by direct inhibition of IKKbeta on Cys-179.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486285

11 July 2018

Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes

1 reference

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11 July 2018

Areal Density Measurement is a Convenient Method for the Determination of Porcine Islet Equivalents without Counting and Sizing Individual Islets

1 reference

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11 July 2018

Global and societal implications of the diabetes epidemic

1 reference

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11 July 2018

A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma

1 reference

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11 July 2018

Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice

1 reference

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25 September 2018

Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity.

1 reference

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25 September 2018

Protective effect of oleanolic acid against beta cell dysfunction and mitochondrial apoptosis: crucial role of ERK-NRF2 signaling pathway.

1 reference

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25 September 2018

Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins

1 reference

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25 September 2018

Under the ROS…thiol network is the principal suspect for autophagy commitment

1 reference

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25 September 2018

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1 reference

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25 September 2018

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10.1016/J.FEBSLET.2014.04.046

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2 June 2020

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2 June 2020

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2 June 2020

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