(Q35802025)

10 August 2017

Serine hydroxymethyltransferase anchors de novo thymidylate synthesis pathway to nuclear lamina for DNA synthesis (English)

1 reference

10 August 2017

Donald D Anderson

1

1 reference

10 August 2017

Collynn F Woeller

2

1 reference

10 August 2017

En-Pei Chiang

3

1 reference

10 August 2017

Barry Shane

4

1 reference

10 August 2017

Patrick J Stover

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

10 January 2012

1 reference

Journal of Biological Chemistry

10 August 2017

1 reference

10 August 2017

287

1 reference

10 August 2017

10

1 reference

10 August 2017

7051-7062

1 reference

Mthfs is an Essential Gene in Mice and a Component of the Purinosome

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Nuclear localization of de novo thymidylate biosynthesis pathway is required to prevent uracil accumulation in DNA

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Histone demethylase LSD1 is a folate-binding protein

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Compartmentalization of Mammalian folate-mediated one-carbon metabolism

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Microtubule-assisted mechanism for functional metabolic macromolecular complex formation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Regulating post-translational modifications of the eukaryotic replication clamp PCNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Cytoplasmic serine hydroxymethyltransferase regulates the metabolic partitioning of methylenetetrahydrofolate but is not essential in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Reversible compartmentalization of de novo purine biosynthetic complexes in living cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

PCNA, the maestro of the replication fork

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

A map of the interactome network of the metazoan C. elegans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

The DNA synthesome: its potential as a novel in vitro model system for studying S-phase specific anticancer agents

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Heavy chain ferritin enhances serine hydroxymethyltransferase expression and de novo thymidine biosynthesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Disruption of nuclear lamin organization blocks the elongation phase of DNA replication

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Intracellular location of thymidylate synthase and its state of phosphorylation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Disruption of nuclear lamin organization alters the distribution of replication factors and inhibits DNA synthesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Multienzyme complex for metabolic channeling in mammalian DNA replication

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Folate-mediated one-carbon metabolism

11 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

Pyridoxal phosphate inhibits dynamic subunit interchange among serine hydroxymethyltransferase tetramers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

A novel fruitfly protein under developmental control degrades uracil-DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.333120

A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

A new pathway expressed during a distinct stage of Drosophila development for the removal of dUMP residues in DNA.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293584

Visualization of replication factories attached to nucleoskeleton

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22235121

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

5-Formyltetrahydrofolate regulates homocysteine remethylation in human neuroblastoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22235121

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.333120

1 reference

10 August 2017

1 reference

10 August 2017

1 reference