(Q46356485)

21 December 2017

title

Folate-mediated one-carbon metabolism (English)

1 reference

21 December 2017

author name string

Jennifer T Fox

series ordinal

1

1 reference

21 December 2017

Patrick J Stover

series ordinal

2

1 reference

21 December 2017

publication date

1 January 2008

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21 December 2017

published in

Vitamins and Hormones

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21 December 2017

volume

79

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21 December 2017

page(s)

1-44

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21 December 2017

DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

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7 January 2021

Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase

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7 January 2021

Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation

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7 January 2021

Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase

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7 January 2021

Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication

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7 January 2021

Introns are essential for growth-regulated expression of the mouse thymidylate synthase gene

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7 January 2021

Regulation of mouse thymidylate synthase gene expression in growth-stimulated cells: upstream S phase control elements are indistinguishable from the essential promoter elements

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7 January 2021

Cell-cycle-directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate

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7 January 2021

Mechanism of reductive activation of cobalamin-dependent methionine synthase: an electron paramagnetic resonance spectroelectrochemical study

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7 January 2021

Nitrous oxide exposure reduces hepatic C1-tetrahydrofolate synthase expression in rats

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7 January 2021

Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme

1 reference

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7 January 2021

Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency

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7 January 2021

Nuclear expression of thymidylate synthase in colorectal cancer cell lines and clinical samples

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7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

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7 January 2021

Coordinate inhibition of DNA synthesis and thymidylate synthase activity following DNA damage and repair

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7 January 2021

Methionine synthase (MTR) 2756 (A --> G) polymorphism, double heterozygosity methionine synthase 2756 AG/methionine synthase reductase (MTRR) 66 AG, and elevated homocysteinemia are three risk factors for having a child with Down syndrome

1 reference

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7 January 2021

The human GARS-AIRS-GART gene encodes two proteins which are differentially expressed during human brain development and temporally overexpressed in cerebellum of individuals with Down syndrome

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7 January 2021

A Polymorphism, R653Q, in the Trifunctional Enzyme Methylenetetrahydrofolate Dehydrogenase/Methenyltetrahydrofolate Cyclohydrolase/Formyltetrahydrofolate Synthetase Is a Maternal Genetic Risk Factor for Neural Tube Defects

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Subcellular Distribution of some Folic Acid-Linked Enzymes in Rat Liver

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The kinetic mechanism of the human bifunctional enzyme ATIC (5-amino-4-imidazolecarboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase). A surprising lack of substrate channeling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

MTR 2756 A > G polymorphism is associated with the risk of systemic lupus erythematosus in the Polish population

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The catalytic mechanism and structure of thymidylate synthase

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Reversion of a Chinese hamster cell auxotrophic mutant

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Human methionine synthase. cDNA cloning, gene localization, and expression

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Structural and functional characterization of a 5,10-methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087).

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Folate and carcinogenesis: an integrated scheme

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Autoregulation of human thymidylate synthase messenger RNA translation by thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Natural antisense (rTSalpha) RNA induces site-specific cleavage of thymidylate synthase mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase from porcine liver. Interaction between the dehydrogenase and cyclohydrolase activities of the multifunctional enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Translational regulation of human methionine synthase by upstream open reading frames

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Evaluation of a methylenetetrahydrofolate-dehydrogenase 1958G>A polymorphism for neural tube defect risk

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mitochondrial NAD-dependent methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase is essential for embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth

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7 January 2021

Atypical variants of nonketotic hyperglycinemia

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

10-formyltetrahydrofolate dehydrogenase requires a 4'-phosphopantetheine prosthetic group for catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Transcriptional control elements and complex initiation pattern of the TATA-less bidirectional human thymidylate synthase promoter

1 reference

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7 January 2021

Maternal genetic effects, exerted by genes involved in homocysteine remethylation, influence the risk of spina bifida

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase

1 reference

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7 January 2021

Mechanism of cytotoxicity of 5,10-dideazatetrahydrofolic acid in human ovarian carcinoma cells in vitro and modulation of the drug activity by folic or folinic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Inhibition of 5,10-methenyltetrahydrofolate synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Structural determinants for the intracellular degradation of human thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A noncatalytic tetrahydrofolate tight binding site is on the small domain of 10-formyltetrahydrofolate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Characterization of the folate-dependent mitochondrial oxidation of carbon 3 of serine

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The human and mouse methylenetetrahydrofolate reductase (MTHFR) genes: genomic organization, mRNA structure and linkage to the CLCN6 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Homocysteine and atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

5-Formyltetrahydrofolate regulates homocysteine remethylation in human neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Role of linkers in communication between protein modules

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Posttranscriptional regulation of mammalian methionine synthase by B12.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The molecular basis of glutamate formiminotransferase deficiency

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https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5'-terminal Regulatory Region of the Human Gene for Thymidylate Synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Effect of nitrous oxide inactivation of vitamin B12-dependent methionine synthetase on the subcellular distribution of folate coenzymes in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Characterization of the rat cytoplasmic C1-tetrahydrofolate synthase gene and analysis of its expression in liver regeneration and fetal development

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mechanism for the coupling of ATP hydrolysis to the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Glycine cleavage system in neurogenic regions

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Control of thymidylate synthase mRNA content and gene transcription in an overproducing mouse cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Thermolabile methylenetetrahydrofolate reductase in patients with coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Characterization of the Zinc Binding Site in Methionine Synthase Enzymes of Escherichia coli : The Role of Zinc in the Methylation of Homocysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Splicing signals are required for S-phase regulation of the mouse thymidylate synthase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

MTHFD 1958G>A and MTR 2756A>G polymorphisms are associated with bipolar disorder and schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Properties of tetrahydropteroylpentaglutamate bound to 10-formyltetrahydrofolate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Ligand-mediated induction of thymidylate synthase occurs by enzyme stabilization. Implications for autoregulation of translation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Towards structure-based drug design: crystal structure of a multisubstrate adduct complex of glycinamide ribonucleotide transformylase at 1.96 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

18Oxygen incorporation into inorganic phosphate in the reaction catalyzed by N5,10-methenyltetrahydrofolate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Polymorphism of the thymidylate synthase gene and outcome of acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Glycine turnover and decarboxylation rate quantified in healthy men and women using primed, constant infusions of [1,2-(13)C2]glycine and [(2)H3]leucine.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Treatment of tetanus; severe bone-marrow depression after prolonged nitrous-oxide anaesthesia.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Site-directed mutagenesis of a potential catalytic and formyl phosphate binding site and substrate inhibition of N10-formyltetrahydrofolate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A meta-analysis of the MTHFR C677T polymorphism and schizophrenia risk

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Identification of a novel single nucleotide polymorphism in the first tandem repeat sequence of the thymidylate synthase 2R allele

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Tyrosine 146 of thymidylate synthase assists proton abstraction from the 5-position of 2'-deoxyuridine 5'-monophosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Structure-based perspectives on B12-dependent enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Tetrahydropterolypolyglutamate derivatives as substrates of two multifunctional proteins with folate-dependent enzyme activities

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A 6 bp polymorphism in the thymidylate synthase gene causes message instability and is associated with decreased intratumoral TS mRNA levels

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Prognostic significance of folate metabolism polymorphisms for lung cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Formation and utilization of formyl phosphate by N10-formyltetrahydrofolate synthetase: evidence for formyl phosphate as an intermediate in the reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Cytosolic biosynthesis of GTP and ATP in normal rat pancreatic islets

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Homocysteine metabolism in pregnancies complicated by neural-tube defects.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

DNA methylation: the nuts and bolts of repression

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Genetic polymorphism of 5,10-methylenetetrahydrofolate reductase (MTHFR) as a risk factor for coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Maternal MTR genotype contributes to the risk of non-syndromic cleft lip and palate in the Polish population

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Hyperhomocysteinemia, methylenetetrahydrofolate reductase 677TT genotype, and the risk for schizophrenia: a Dutch population based case-control study

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The two monofunctional domains of octameric formiminotransferase-cyclodeaminase exist as dimers

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

In silico experimentation with a model of hepatic mitochondrial folate metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Rapid incorporation of label from ribonucleoside disphosphates into DNA by a cell-free high molecular weight fraction from animal cell nuclei

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Crystal structure of human T-protein of glycine cleavage system at 2.0 A resolution and its implication for understanding non-ketotic hyperglycinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A B12-responsive internal ribosome entry site (IRES) element in human methionine synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Heavy chain ferritin enhances serine hydroxymethyltransferase expression and de novo thymidine biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

5,10 Methylenetetrahydrofolate reductase genetic polymorphism as a risk factor for neural tube defects

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

MTHFD1 R653Q polymorphism is a maternal genetic risk factor for severe abruptio placentae

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Methenyltetrahydrofolate cyclohydrolase is rate limiting for the enzymatic conversion of 10-formyltetrahydrofolate to 5,10-methylenetetrahydrofolate in bifunctional dehydrogenase-cyclohydrolase enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Transcriptional regulation of murine NADP(+)-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

NAD(+)-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase: detection of the mRNA in normal murine tissues and transcriptional regulation of the gene in cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mimosine attenuates serine hydroxymethyltransferase transcription by chelating zinc. Implications for inhibition of DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The effect of nitrous oxide-induced inactivation of vitamin B12 on the activity of formyl-methenyl-methylenetetrahydrofolate synthetase, methylene-tetrahydrofolate reductase and formiminotetrahydrofolate transferase.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The metabolism of serine and glycine in mutant lines of Chinese hamster ovary cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Regulatory studies of murine methylenetetrahydrofolate reductase reveal two major promoters and NF-kappaB sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Inhibition of the mammalian transcription factor LSF induces S-phase-dependent apoptosis by downregulating thymidylate synthase expression

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Human mitochondrial C1-tetrahydrofolate synthase: gene structure, tissue distribution of the mRNA, and immunolocalization in Chinese hamster ovary calls

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Multienzyme complex for metabolic channeling in mammalian DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A quantum chemical study of the water-assisted mechanism in one-carbon unit transfer reaction catalyzed by glycinamide ribonucleotide transformylase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Red blood cell methylfolate and plasma homocysteine as risk factors for venous thromboembolism: a matched case-control study

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Homocysteine and cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The crystal structure of human cytosolic serine hydroxymethyltransferase: a target for cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Synergistic activation of the TATA-less mouse thymidylate synthase promoter by the Ets transcription factor GABP and Sp1.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Intracellular location of thymidylate synthase and its state of phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Activities of hepatic cytosolic and mitochondrial forms of serine hydroxymethyltransferase and hepatic glycine concentration are affected by vitamin B-6 intake in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Migraine and MTHFR C677T genotype in a population-based sample

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Formyl-methenyl-methylenetetrahydrofolate synthetase from rabbit liver (combined). Evidence for a single site in the conversion of 5,10-methylenetetrahydrofolate to 10-formyltetrahydrofolate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Interaction of folylpolyglutamates with enzymes in one-carbon metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Serine hydroxymethyltransferase revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

How does folic acid prevent neural tube defects?

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The association-dissociation of formyltetrahydrofolate synthetase and its relation to monovalent cation activation of catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Pathogenesis of subacute combined degeneration: a result of methyl group deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Vitamin B12-folate interrelationships

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Evaluation of the catalytic mechanism of AICAR transformylase by pH-dependent kinetics, mutagenesis, and quantum chemical calculations

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Inhibition of progression of aberrant crypt foci and colon tumor development by vitamin E and beta-carotene in rats on a high-risk diet

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Function of yeast cytoplasmic C1-tetrahydrofolate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Solvent oxygen is not incorporated into N10-formyltetrahydrofolate in the reaction catalyzed by N10-formyltetrahydrofolate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Interaction of mitochondrial initiation factor 2 with mitochondrial fMet-tRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Metabolic compartmentation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Methylation demand and homocysteine metabolism: effects of dietary provision of creatine and guanidinoacetate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Linkage disequilibrium of MTHFR genotypes 677C/T-1298A/C in the German population and association studies in probands with neural tube defects(NTD)

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Association of polymorphisms in one-carbon metabolism genes and postmenopausal breast cancer incidence

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The metabolic role of leucovorin

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Evidence that 5-formyltetrahydropteroylglutamate has a metabolic role in one-carbon metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

In vitro conversion of formate to serine: effect of tetrahydropteroylpolyglutamates and serine hydroxymethyltransferase on the rate of 10-formyltetrahydrofolate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

New perspectives on folate catabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Targeted disruption of the methionine synthase gene in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Structure of a murine cytoplasmic serine hydroxymethyltransferase quinonoid ternary complex: evidence for asymmetric obligate dimers

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Serine hydroxymethyltransferase: role of glu75 and evidence that serine is cleaved by a retroaldol mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Nucleotide sequence of a functional cDNA for human thymidylate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Folate-based thymidylate synthase inhibitors in cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mammalian mitochondrial methionyl-tRNA transformylase from bovine liver. Purification, characterization, and gene structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Stereochemistry of methylene transfer involving 5,10-methylenetetrahydrofolate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mammalian mitochondrial initiation factor 2 supports yeast mitochondrial translation without formylated initiator tRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Folate activation and catalysis in methylenetetrahydrofolate reductase from Escherichia coli: roles for aspartate 120 and glutamate 28.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Thymidylate synthase: a novel genetic determinant of plasma homocysteine and folate levels

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Crystal structure of binary and ternary complexes of serine hydroxymethyltransferase from Bacillus stearothermophilus: insights into the catalytic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The controversy over homocysteine and cardiovascular risk

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Neural tube defects and a disturbed folate dependent homocysteine metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

The role of the 5' untranslated region of an mRNA in translation regulation during development

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Mitochondrial methionyl-tRNAfMet formyltransferase from Saccharomyces cerevisiae: gene disruption and tRNA substrate specificity.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Associations between polymorphisms within the thymidylate synthase gene and spina bifida

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Enzymatic characterization of human mitochondrial C1-tetrahydrofolate synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Human AICAR transformylase: role of the 4-carboxamide of AICAR in binding and catalysis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Kinetic relationships between the various activities of the formyl-methenyl-methylenetetrahydrofolate synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Observations on the monovalent cation requirements of formyltetrahydrofolate synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Targeting Ras signaling through inhibition of carboxyl methylation: An unexpected property of methotrexate

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Identification of folate binding protein of mitochondria as dimethylglycine dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

A ferritin-responsive internal ribosome entry site regulates folate metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Structural insights into the avian AICAR transformylase mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Nuclear thymidylate synthase expression, p53 expression and 5FU response in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Regulation of human methylenetetrahydrofolate reductase by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

De novo purine nucleotide biosynthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementatio

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

Compartmentation of folate-mediated one-carbon metabolism in eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2808%2900401-9

7 January 2021

10.1016/S0083-6729(08)00401-9

Identifiers

DOI

1 reference

21 December 2017

1 reference

21 December 2017