(Q35803002)

10 August 2017

Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man (English)

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10 August 2017

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H H Kupferschmidt

1

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10 August 2017

K E Fattinger

2

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10 August 2017

H R Ha

3

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10 August 2017

F Follath

4

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10 August 2017

S Krähenbühl

5

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10 August 2017

language of work or name

English

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publication date

1 April 1998

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British Journal of Clinical Pharmacology

10 August 2017

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10 August 2017

45

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10 August 2017

4

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10 August 2017

355-359

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Saquinavir pharmacokinetics alone and in combination with ritonavir in HIV-infected patients

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Saquinavir. A review of its pharmacology and clinical potential in the management of HIV infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

The effect of high-dose saquinavir on viral load and CD4+ T-cell counts in HIV-infected patients.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Effect of itraconazole and terbinafine on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Therapy for human immunodeficiency virus infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

The effect of erythromycin on the pharmacokinetics and pharmacodynamics of zopiclone

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Active human immunodeficiency virus protease is required for viral infectivity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

An inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Rational design of peptide-based HIV proteinase inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Interaction of citrus juices with felodipine and nifedipine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

The statistical sign test.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Interaction between grapefruit juice and midazolam in humans*

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine*

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1873963

Hepatic blood flow and drug metabolism in patients on enzyme-inducing anticonvulsants

25 September 2018

1 reference

12 December 2020

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues

1 reference

12 December 2020

Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin

1 reference

12 December 2020

Safety and activity of saquinavir in HIV infection

1 reference

12 December 2020

Effect of grapefruit juice on blood cyclosporin concentration

1 reference

12 December 2020

Erythromycin-felodipine interaction: Magnitude, mechanism, and comparison with grapefruit juice*

1 reference

12 December 2020

Identification of 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice

1 reference

12 December 2020

Determination of saquinavir in human plasma by high-performance liquid chromatography

1 reference

12 December 2020

10.1046/J.1365-2125.1998.T01-1-00687.X

Identifiers

DOI

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10 August 2017

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10 August 2017

PubMed publication ID

9578182

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