(Q35806374)

10 August 2017

Increased extracellular pressure stimulates tumor proliferation by a mechanosensitive calcium channel and PKC-β. (English)

1 reference

10 August 2017

Marc D Basson

1

1 reference

10 August 2017

Bixi Zeng

2

1 reference

10 August 2017

Christina Downey

3

1 reference

10 August 2017

Madhu P Sirivelu

4

1 reference

10 August 2017

Jetze J Tepe

5

1 reference

10 August 2017

language of work or name

1 reference

23 October 2014

1 reference

10 August 2017

1 reference

10 August 2017

9

1 reference

10 August 2017

2

1 reference

10 August 2017

513-526

1 reference

Releasing pressure in tumors: what do we know so far and where do we go from here? A review

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Influence of defunctionalization and mechanical forces on intestinal epithelial wound healing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Isoform-specific modulation of pressure-stimulated cancer cell proliferation and adhesion by α-actinin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Mechanical stress activates Smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Molecular basis of lysophosphatidic acid-induced NF-κB activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Structural-activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-kappaB mediated IL-6 production.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Mechanics, malignancy, and metastasis: the force journey of a tumor cell

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

IKK-2 is required for TNF-alpha-induced invasion and proliferation of human mesenchymal stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Calcium signalling and cancer cell growth.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

An intracellular signal pathway that regulates cancer cell adhesion in response to extracellular forces

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

NF-kappaB as a potential molecular target for cancer therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

T-type Ca2+ channel expression in human esophageal carcinomas: a functional role in proliferation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Mechanosensitive ion channels in interstitial cells of Cajal and smooth muscle of the gastrointestinal tract

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Src and focal adhesion kinase mediate mechanical strain-induced proliferation and ERK1/2 phosphorylation in human H441 pulmonary epithelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Aspirin activates the NF-kappaB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Differential regulation of monocyte/macrophage cytokine production by pressure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Tensional homeostasis and the malignant phenotype

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Emergent patterns of growth controlled by multicellular form and mechanics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

NF-kB in development and progression of human cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Extracellular pressure stimulates colon cancer cell proliferation via a mechanism requiring PKC and tyrosine kinase signals

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Mechanosensitivity of N-type calcium channel currents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

PKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Overexpression of an alpha 1H (Cav3.2) T-type calcium channel during neuroendocrine differentiation of human prostate cancer cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Sequential activation of protein kinase C (PKC)-alpha and PKC-epsilon contributes to sustained Raf/ERK1/2 activation in endothelial cells under mechanical strain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Molecular basis of mechanotransduction in living cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Dipole potentials indicate restructuring of the membrane interface induced by gadolinium and beryllium ions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Exposure of human vascular endothelial cells to sustained hydrostatic pressure stimulates proliferation. Involvement of the alphaV integrins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Applied pressure enhances cell proliferation through mitogen-activated protein kinase activation in mesangial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Tensegrity: the architectural basis of cellular mechanotransduction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

The cloning of a mechano-gated membrane ion channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Transduction of membrane tension by the ion channel alamethicin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Effects of cytochalasin and phalloidin on actin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Block of stretch-activated ion channels in Xenopus oocytes by gadolinium and calcium ions.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

SK&F 96365, a novel inhibitor of receptor-mediated calcium entry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Quantitative video microscopy of patch clamped membranes stress, strain, capacitance, and stretch channel activation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Mechanosensitive ion channels of E. coli activated by amphipaths.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Interstitial hypertension in head and neck tumors in patients: correlation with tumor size.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Rapid adaptation of single mechanosensitive channels in Xenopus oocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

The Ca(2+) channel antagonists mibefradil and pimozide inhibit cell growth via different cytotoxic mechanisms

27 July 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Cytoskeletal signaling by way of alpha-actinin-1 mediates ERK1/2 activation by repetitive deformation in human Caco2 intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Can cancer be reversed by engineering the tumor microenvironment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Nickel block of three cloned T-type calcium channels: low concentrations selectively block alpha1H.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Protein kinase C, an elusive therapeutic target?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Stereoselective synthesis of highly substituted Delta1-pyrrolines: exo-selective 1,3-dipolar cycloaddition reactions with azlactones

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

High interstitial fluid pressure in rat tongue cancer is related to increased lymph vessel area, tumor size, invasiveness and decreased body weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Interstitial stress and fluid pressure within a growing tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Extracellular pressure stimulates macrophage phagocytosis by inhibiting a pathway involving FAK and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Phosphorylation of the CARMA1 linker controls NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

La(3+) and Gd(3+) induce shape change of giant unilamellar vesicles of phosphatidylcholine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Integrin and FAK-mediated MAPK activation is required for cyclic strain mitogenic effects in Caco-2 cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

Strain induces Caco-2 intestinal epithelial proliferation and differentiation via PKC and tyrosine kinase signals.

25 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4487881

25 September 2018

12 December 2020

High tumor interstitial fluid pressure identifies cervical cancer patients with improved survival from radiotherapy plus cisplatin versus radiotherapy alone

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Expression of NF-?B in prostate cancer lymph node metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.MOLONC.2014.10.008

Alpha-actinin-1 phosphorylation modulates pressure-induced colon cancer cell adhesion through regulation of focal adhesion kinase-Src interaction

21 January 2018

1 reference

12 December 2020

Pressure-induced vascular activation of nuclear factor-kappaB: role in cell survival

1 reference

12 December 2020

Modulation of human CACO-2 intestinal epithelial cell phenotype by protein kinase C inhibitors

1 reference

12 December 2020

NF-kappaB responds to mechanical strains in osteoblast-like cells, and lighter strains create an NF-kappaB response more readily

1 reference

12 December 2020

Assembly dynamics of actin in adherent human neutrophils

1 reference

12 December 2020

Interstitial hypertension in human breast and colorectal tumors

1 reference

12 December 2020

PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells

1 reference

12 December 2020

An Autoradiographic and Pathological Study of Cellular Proliferation in Rabbit Arteries Correlated with an Increase in Arterial Pressure

1 reference

12 December 2020

Pressure-activated cation channel in intact rat endocardial endothelium

1 reference

12 December 2020

Inhibition of mechanical strain-induced fetal rat lung cell proliferation by gadolinium, a stretch-activated channel blocker

1 reference

12 December 2020

10.1016/J.MOLONC.2014.10.008

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference