(Q51486103)

English

Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1.

scientific article published on 6 November 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

Repetitive deformation activates focal adhesion kinase and ERK mitogenic signals in human Caco-2 intestinal epithelial cells through Src and Rac1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

1 reference

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Lakshmi S Chaturvedi

1

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

H Michael Marsh

2

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

Xun Shang

3

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

Yi Zheng

4

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

Marc D Basson

5

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

language of work or name

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publication date

6 November 2006

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

282

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

1

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

14-28

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

Amplitude-dependent modulation of brush border enzymes and proliferation by cyclic strain in human intestinal Caco-2 monolayers

1 reference

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21 January 2018

Human enterocyte (Caco-2) migration is modulated in vitro by extracellular matrix composition and epidermal growth factor

1 reference

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21 January 2018

Regulation of the intestinal epithelial response to cyclic strain by extracellular matrix proteins

1 reference

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21 January 2018

Effects of glutamine isomers on human (Caco-2) intestinal epithelial proliferation, strain-responsiveness, and differentiation.

1 reference

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21 January 2018

Uniaxial cyclic stretch induces focal adhesion kinase (FAK) tyrosine phosphorylation followed by mitogen-activated protein kinase (MAPK) activation

1 reference

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21 January 2018

Repetitive deformation and pressure activate small bowel and colonic mucosal tyrosine kinase activity in vivo

1 reference

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21 January 2018

Src autophosphorylation is an early event in pressure-mediated signaling pathways in isolated resistance arteries

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21 January 2018

Mechanical strain induces pp60src activation and translocation to cytoskeleton in fetal rat lung cells

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21 January 2018

Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells

1 reference

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21 January 2018

Conversion of mechanical force into biochemical signaling

1 reference

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21 January 2018

Guanosine 5'-3-O-(thio)triphosphate stimulates tyrosine phosphorylation of p125FAK and paxillin in permeabilized Swiss 3T3 cells. Role of p21rho

1 reference

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21 January 2018

Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts

1 reference

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21 January 2018

Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation

1 reference

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21 January 2018

Cyclic mechanical strain inhibits skeletal myogenesis through activation of focal adhesion kinase, Rac-1 GTPase, and NF-kappaB transcription factor

1 reference

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21 January 2018

External mechanical strain regulates membrane targeting of Rho GTPases by controlling microtubule assembly

1 reference

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21 January 2018

ERK activation by mechanical strain is regulated by the small G proteins rac-1 and rhoA.

1 reference

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21 January 2018

PKC mediates cyclic stretch-induced cardiac hypertrophy through Rho family GTPases and mitogen-activated protein kinases in cardiomyocytes

1 reference

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21 January 2018

Effects of cell tension on the small GTPase Rac

1 reference

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21 January 2018

Effect of mechanical strain on gastric cellular migration and proliferation during mucosal healing: role of Rho dependent and Rac dependent cytoskeletal reorganisation

1 reference

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21 January 2018

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

1 reference

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21 January 2018

Treatment of rat proximal and distal colonic cells with sodium orthovanadate enhances their adhesion and survival in primary culture.

1 reference

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21 January 2018

Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress

1 reference

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21 January 2018

Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Cyclic stretch-induced cPLA2 mediates ERK 1/2 signaling in rabbit proximal tubule cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

MAP and src kinases control the induction of AP-1 members in response to changes in mechanical environment in osteoblastic cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs

1 reference

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21 January 2018

Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Biochemical signals and biological responses elicited by the focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Focal adhesion kinase promotes phospholipase C-gamma1 activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v-Src, but is not a critical determinant of v-Src transformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Mechanisms of focal adhesion kinase regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Association of focal adhesion kinase with Grb7 and its role in cell migration

1 reference

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21 January 2018

Extracellular pressure stimulates tumor cell adhesion in vitro by paxillin activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605817200

21 January 2018

Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis

1 reference

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21 January 2018

Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

1 reference

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21 January 2018

Regulation of Akt-dependent cell survival by Syk and Rac.

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21 January 2018

Interleukin-1beta induces a reactive astroglial phenotype via deactivation of the Rho GTPase-Rock axis.

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Emodin inhibits tumor cell migration through suppression of the phosphatidylinositol 3-kinase-Cdc42/Rac1 pathway.

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Fibroblast growth factor-2 and remodeled type I collagen control membrane protrusion in human vascular smooth muscle cells: biphasic activation of Rac1.

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21 January 2018

Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells

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21 January 2018

p85 beta-PIX is required for cell motility through phosphorylations of focal adhesion kinase and p38 MAP kinase

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Dominant-negative Rac increases both inherent and ionizing radiation-induced cell migration in C6 rat glioma cells

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21 January 2018

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

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A rapid, nongenomic, signaling pathway regulates the actin reorganization induced by activation of membrane testosterone receptors

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Distinct signaling pathways regulate differential opioid effects on actin cytoskeleton in malignant MCF7 and nonmalignant MCF12A human breast epithelial cells

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The opioid agonist ethylketocyclazocine reverts the rapid, non-genomic effects of membrane testosterone receptors in the human prostate LNCaP cell line

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21 January 2018

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

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21 January 2018

A role for Mer tyrosine kinase in alphavbeta5 integrin-mediated phagocytosis of apoptotic cells.

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Platelet-derived growth factor induces the beta-gamma-secretase-mediated cleavage of Alzheimer's amyloid precursor protein through a Src-Rac-dependent pathway.

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21 January 2018

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

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21 January 2018

Modulation of vascular smooth muscle cell alignment by cyclic strain is dependent on reactive oxygen species and P38 mitogen-activated protein kinase

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21 January 2018

Differential regulation of vascular focal adhesion kinase by steady stretch and pulsatility

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21 January 2018

Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart

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21 January 2018

Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells

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21 January 2018

Demonstration of a direct stimulatory effect of bile salts on rat colonic epithelial cell proliferation

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Comparison of the effects of concanavalin-A and epidermal growth factor on epithelial cell proliferation in the rat intestine

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Identifiers

10.1074/JBC.M605817200

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 April 2018

http://europepmc.org/abstract/MED/17088251

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