(Q35806733)

10 August 2017

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title

Folate, colorectal carcinogenesis, and DNA methylation: lessons from animal studies (English)

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10 August 2017

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Young-In Kim

1

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10 August 2017

publication date

1 January 2004

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Environmental and Molecular Mutagenesis

10 August 2017

published in

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10 August 2017

volume

44

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10 August 2017

issue

1

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10 August 2017

page(s)

10-25

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DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

10 August 2017

cites work

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Hepatic one-carbon metabolism in early folate deficiency in rats

21 January 2018

1 reference

The role of folic acid and Vitamin B12 in genomic stability of human cells

21 January 2018

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Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study

21 January 2018

1 reference

Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism

21 January 2018

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Folic acid supplements and fortification affect the risk for neural tube defects, vascular disease and cancer: evolving science

21 January 2018

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7 January 2021

Methyl Group Metabolism in the Pancreas of Folate-Deficient Rats

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7 January 2021

DNA methylation in folate deficiency: use of CpG methylase

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7 January 2021

Experimental models of colorectal cancer.

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7 January 2021

Prevention of neural-tube defects with folic acid in China. China-U.S. Collaborative Project for Neural Tube Defect Prevention

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7 January 2021

Delayed Tumor Onset in Transgenic Mice Fed a Low-Folate Diet

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7 January 2021

Role of aberrant crypt foci in understanding the pathogenesis of colon cancer

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7 January 2021

Molecular genetics of hereditary nonpolyposis colorectal cancer.

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7 January 2021

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

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7 January 2021

Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis.

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7 January 2021

What can randomized controlled trials tell us about nutrition and cancer prevention?

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7 January 2021

DNA hypomethylation leads to elevated mutation rates

1 reference

7 January 2021

Folate status: effects on pathways of colorectal carcinogenesis

1 reference

7 January 2021

Biochemical and molecular aberrations in the rat colon due to folate depletion are age-specific

1 reference

7 January 2021

Folic acid fortification increases red blood cell folate concentrations in the Framingham study

1 reference

7 January 2021

Folic acid intake from fortification in United States exceeds predictions

1 reference

7 January 2021

Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency.

1 reference

7 January 2021

DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation

1 reference

7 January 2021

Microsatellite instability in non-neoplastic mucosa of patients with ulcerative colitis: effect of folate supplementation

1 reference

7 January 2021

Effect of folate supplementation on DNA methylation of rectal mucosa in patients with colonic adenomas: correlation with nutrient intake

1 reference

7 January 2021

Alterations in expression and methylation of specific genes in livers of rats fed a cancer promoting methyl-deficient diet

1 reference

7 January 2021

Folic acid deficiency and cancer: mechanisms of DNA instability

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7 January 2021

Folate Deficiency In Vitro Induces Uracil Misincorporation and DNA Hypomethylation and Inhibits DNA Excision Repair in Immortalized Normal Human Colon Epithelial Cells

1 reference

7 January 2021

DNA stability and genomic methylation status in colonocytes isolated from methyl-donor-deficient rats

1 reference

7 January 2021

Colorectal cancer complicating ulcerative colitis: a review

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7 January 2021

The risk of colorectal cancer in ulcerative colitis: a meta-analysis

1 reference

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

7 January 2021

Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults

1 reference

7 January 2021

Plasma folate levels and risk of spontaneous abortion

1 reference

7 January 2021

Epidemiologic studies of folate and colorectal neoplasia: a review

1 reference

7 January 2021

1,2-Dimethylhydrazine-induced premalignant alterations in the S-adenosylmethionine/S-adenosylhomocysteine ratio and membrane lipid lateral diffusion of the rat distal colon

1 reference

7 January 2021

The effects of alcohol on folate metabolism

1 reference

7 January 2021

Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis

1 reference

7 January 2021

Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects

1 reference

7 January 2021

Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women

1 reference

7 January 2021

The effect of folic acid fortification on plasma folate and total homocysteine concentrations

1 reference

7 January 2021

Impact of extracellular folate levels on global gene expression

1 reference

7 January 2021

The fundamental role of epigenetic events in cancer

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7 January 2021

Cancer epigenetics comes of age

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7 January 2021

Effect of folate supplementation on mucosal cell proliferation in high risk patients for colon cancer

1 reference

7 January 2021

Folate and carcinogenesis: evidence, mechanisms, and implications

1 reference

7 January 2021

Methylenetetrahydrofolate reductase polymorphisms, folate, and cancer risk: a paradigm of gene-nutrient interactions in carcinogenesis.

1 reference

7 January 2021

Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver

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7 January 2021

Dietary folate protects against the development of macroscopic colonic neoplasia in a dose responsive manner in rats

1 reference

7 January 2021

Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene

1 reference

7 January 2021

Colonic mucosal concentrations of folate correlate well with blood measurements of folate status in persons with colorectal polyps

1 reference

7 January 2021

Effects of folate supplementation on two provisional molecular markers of colon cancer: a prospective, randomized trial

1 reference

7 January 2021

Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms

1 reference

7 January 2021

Red blood cell folate is associated with the development of dysplasia and cancer in ulcerative colitis

1 reference

7 January 2021

The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis

1 reference

7 January 2021

Trends in serum folate after food fortification.

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7 January 2021

Folate deficiency diminishes the occurrence of aberrant crypt foci in the rat colon but does not alter global DNA methylation status.

1 reference

7 January 2021

Folate deficiency reduces the development of colorectal cancer in rats

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7 January 2021

DNA methylation and genetic instability in colorectal cancer cells

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7 January 2021

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

1 reference

7 January 2021

Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. MRC Vitamin Study Research Group

1 reference

7 January 2021

Folic acid deficiency and methyl group metabolism in rat brain: effects of L-dopa.

1 reference

7 January 2021

Folate supplementation and adenomatous colonic polyps.

1 reference

7 January 2021

Differential sensitivity to loss of cytosine methyl groups within the hepatic p53 gene of folate/methyl deficient rats

1 reference

7 January 2021

Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat

1 reference

7 January 2021

Methyl supply, methyl metabolizing enzymes and colorectal neoplasia

1 reference

7 January 2021

Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study

1 reference

7 January 2021

Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.

1 reference

7 January 2021

Meta-analysis of hyperhomocysteinemia as a risk factor for venous thromboembolic disease.

1 reference

7 January 2021

Increased red cell folate concentrations in women of reproductive age after Canadian folic acid food fortification

1 reference

7 January 2021

Rodent models for carcinoma of the colon

1 reference

7 January 2021

The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine

1 reference

7 January 2021

Plasma homocysteine as a risk factor for dementia and Alzheimer's disease

1 reference

7 January 2021

Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice

1 reference

7 January 2021

The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon

1 reference

7 January 2021

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

1 reference

7 January 2021

Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine study

1 reference

7 January 2021

Comparison of methyltransferase activities of pair-fed rats given adequate or methyl-deficient diets.

1 reference

7 January 2021

Folate Deficiency in Rats Fed Diets Containing Free Amino Acids or Intact Proteins

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7 January 2021

Efficacy of potential chemopreventive agents on rat colon aberrant crypt formation and progression.

1 reference

7 January 2021

Prevalence of spina bifida and anencephaly during the transition to mandatory folic acid fortification in the United States

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7 January 2021

Colorectal cancer screening: clinical guidelines and rationale

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7 January 2021

The onset of oncogene hypomethylation in the livers of rats fed methyl-deficient, amino acid-defined diets

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7 January 2021

Identifiers

DOI

10.1002/EM.20025

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10 August 2017

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