(Q35807732)

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Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network

scientific article published on 15 February 2012

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

10

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Matti Nykter

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Kristen M Holmes

1

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Europe PubMed Central

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23 January 2020

Matti Annala

2

1 reference

Europe PubMed Central

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23 January 2020

Corrine Y X Chua

3

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23 January 2020

Sarah M Dunlap

4

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23 January 2020

Yuexin Liu

5

1 reference

Europe PubMed Central

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23 January 2020

Niek Hugen

6

1 reference

Europe PubMed Central

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23 January 2020

Lynette M Moore

7

1 reference

Europe PubMed Central

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23 January 2020

David Cogdell

8

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Europe PubMed Central

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23 January 2020

Limei Hu

9

1 reference

Europe PubMed Central

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23 January 2020

Kenneth Hess

11

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Europe PubMed Central

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23 January 2020

Wei Zhang

13

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Europe PubMed Central

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23 January 2020

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publication date

15 February 2012

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23 January 2020

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

109

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

3475-3480

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Oncogene interactions are required for glioma development and progression as revealed by a tissue specific transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Mouse models for cancer research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Integrin-linked kinase regulates melanoma angiogenesis by activating NF-κB/interleukin-6 signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Integrin signalling adaptors: not only figurants in the cancer story

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Integrins as therapeutic targets: lessons and opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

QLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatmen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Aberrant NF-kappaB activity is critical in focal necrosis formation of human glioblastoma by regulation of the expression of tissue factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Blockade of tumor growth due to matrix metalloproteinase-9 inhibition is mediated by sequential activation of beta1-integrin, ERK, and NF-kappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

NF-kappaB controls growth of glioblastomas/astrocytomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Insulin-like growth factor binding protein 2 promotes glioma development and progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

IGF-independent effects of IGFBP-2 on the human breast cancer cell line Hs578T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Insulin-like growth factor binding protein 2: gene expression microarrays and the hypothesis-generation paradigm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

A mouse model for glioma: biology, pathology, and therapeutic opportunities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Functional role of insulin-like growth factor binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Activated conformations of very late activation integrins detected by a group of antibodies (HUTS) specific for a novel regulatory region (355-425) of the common beta 1 chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3295320

27 July 2018

An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120375109

21 January 2018

Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120375109

21 January 2018

Integrin-linked kinase regulates inducible nitric oxide synthase and cyclooxygenase-2 expression in an NF-kappa B-dependent manner

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120375109

21 January 2018

Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1120375109

21 January 2018

Reactivation of insulin-like growth factor binding protein 2 expression in glioblastoma multiforme: a revelation by parallel gene expression profiling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22345562

12 December 2020

based on heuristic

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10.1073/PNAS.1120375109

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22345562%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2012PNAS..109.3475H

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Europe PubMed Central

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23 January 2020

PubMed publication ID

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Europe PubMed Central

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23 January 2020

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