(Q35816882)

10 August 2017

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations (English)

1 reference

genome-wide association study

10 August 2017

0 references

author

Jane Worthington

33

1 reference

10 August 2017

16

Gabriela Riemekasten

1 reference

10 August 2017

Øyvind Palm

24

0 references

Annika Nordin

Annika Nordin

26

0 references

Jose-Ezequiel Martin

Jose-Ezequiel Martin

2

0 references

Lara Bossini-Castillo

Lara Bossini-Castillo

1

0 references

Ivan Castellvi

Ivan Castellví

9

0 references

Patricia E Carreira

Patricia Carreira

10

0 references

Paul G Shiels

Paul Shiels

30

0 references

Ariane I. Herrick

Ariane Herrick

32

0 references

Javier Martin

Javier Martin

42

0 references

Nicolas Hunzelmann

18

Nicolas Hunzelmann

1 reference

10 August 2017

5

Carmen P Simeón

1 reference

10 August 2017

Mónica Fernández Castro

12

Mónica Fernández Castro

1 reference

10 August 2017

38

Shervin Assassi

1 reference

10 August 2017

40

Maureen D Mayes

1 reference

10 August 2017

35

Filemon K Tan

1 reference

10 August 2017

Timothy R D J Radstake

41

Timothy R D J Radstake

1 reference

10 August 2017

15

Marieke J H Coenen

1 reference

10 August 2017

7

Madelon C Vonk

1 reference

10 August 2017

22

Alexandre E Voskuyl

1 reference

10 August 2017

3

Jasper Broen

1 reference

10 August 2017

25

Roger Hesselstrand

1 reference

10 August 2017

19

Alexander Kreuter

1 reference

10 August 2017

17

Torsten Witte

1 reference

10 August 2017

6

Lorenzo Beretta

1 reference

10 August 2017

21

Bobby P Koeleman

1 reference

10 August 2017

29

Raffaella Scorza

1 reference

10 August 2017

28

Claudio Lunardi

1 reference

10 August 2017

M.Carmen Fonseca-Mora

39

Carmen Fonseca

1 reference

10 August 2017

20

Jörg H W Distler

1 reference

Francisco J. García-Hernandez

10 August 2017

11

Francisco José García-Hernández

1 reference

10 August 2017

27

Paolo Airó

1 reference

10 August 2017

23

Annemie J Schuerwegh

1 reference

10 August 2017

36

Frank C Arnett

1 reference

10 August 2017

4

Olga Gorlova

1 reference

10 August 2017

Jose Luis Callejas

8

1 reference

10 August 2017

Spanish Scleroderma Group

13

1 reference

10 August 2017

Spanish Scleroderma Group

14

1 reference

10 August 2017

Jacob M van Laar

31

1 reference

10 August 2017

Christopher Denton

34

1 reference

10 August 2017

Sandeep K Agarwal

37

1 reference

10 August 2017

10 November 2011

1 reference

10 August 2017

Human Molecular Genetics

1 reference

10 August 2017

21

1 reference

10 August 2017

4

1 reference

10 August 2017

926-933

1 reference

Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

The genetics of scleroderma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

LocusZoom: regional visualization of genome-wide association scan results

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Interleukin-12 receptor beta2: from cytokine receptor to gatekeeper gene in human B-cell malignancies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Genetic structure of Europeans: a view from the North-East

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Recent advances in the genetics of autoimmune disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Signalling, inflammation and arthritis: crossed signals: the role of interleukin (IL)-12, -17, -23 and -27 in autoimmunity.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Replication of an association between IL23R gene polymorphism with inflammatory bowel disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemic sclerosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Criteria for the classification of early systemic sclerosis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

The critical role of IL-12 and the IL-12R beta 2 subunit in the generation of pathogenic autoreactive Th1 cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Requirement for distinct Janus kinases and STAT proteins in T cell proliferation versus IFN-gamma production following IL-12 stimulation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Role of rs1343151 IL23R and rs3790567 IL12RB2 polymorphisms in biopsy-proven giant cell arteritis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

The pathogenesis of systemic sclerosis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Detecting shared pathogenesis from the shared genetics of immune-related diseases

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

T cell polarization identifies distinct clinical phenotypes in scleroderma lung disease.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

Longitudinal analysis of serum cytokine concentrations in systemic sclerosis: association of interleukin 12 elevation with spontaneous regression of skin sclerosis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

24 September 2018

IL-12 in autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3298110

The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDR522

The interleukin 23 receptor gene does not confer risk to systemic sclerosis and is not associated with systemic sclerosis disease phenotype

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDR522

IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population

21 January 2018

1 reference

12 December 2020

IL-12 receptor beta 2 (IL-12R beta 2)-deficient mice are defective in IL-12-mediated signaling despite the presence of high affinity IL-12 binding sites

1 reference

12 December 2020

Levels of interleukin 12, a cytokine of type 1 helper T cells, are elevated in sera from patients with systemic sclerosis

1 reference

12 December 2020

Effect of IL-12 encoding plasmid administration on tight-skin mouse

1 reference

12 December 2020

BAL cytokine profile in different interstitial lung diseases: a focus on systemic sclerosis

1 reference

12 December 2020

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

1 reference

12 December 2020

Lack of Il12rb2 signaling predisposes to spontaneous autoimmunity and malignancy

1 reference

12 December 2020

The role of IL-4 and IL-12 in the regulation of collagen synthesis by fibroblasts

1 reference

12 December 2020

IL23R: a susceptibility locus for celiac disease and multiple sclerosis?

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDR522

1 reference

10 August 2017

1 reference

10 August 2017

1 reference