(Q35821609)

10 August 2017

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title

Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system (English)

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ubiquitin-proteasome system

10 August 2017

main subject

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Leonardo Petrucelli

1

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10 August 2017

Ted M Dawson

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

1 January 2004

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10 August 2017

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10 August 2017

volume

36

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10 August 2017

issue

4

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10 August 2017

page(s)

315-320

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10 August 2017

cites work

Conformational disease

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

The ubiquitin-proteasome proteolytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

The ubiquitin pathway in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Rare genetic mutations shed light on the pathogenesis of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Cellular co-localization of phosphorylated tau- and NACP/alpha-synuclein-epitopes in lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Lewy bodies and parkinsonism in families with parkin mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

A Drosophila model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Proteasomal function is impaired in substantia nigra in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Degradation signals for ubiquitin system proteolysis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

A transgenic mouse model of the ubiquitin/proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

Case-control study of the extended tau gene haplotype in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07853890410031948

10.1080/07853890410031948

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference