(Q35824820)

10 August 2017

Th17-type cytokines, IL-6 and TNF-α synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth (English)

1 reference

10 August 2017

1 reference

1 reference

1 reference

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

V De Simone

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

E Franzè

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

G Ronchetti

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

A Colantoni

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

M C Fantini

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

D Di Fusco

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

G S Sica

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

P Sileri

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

T T MacDonald

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

F Pallone

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

G Monteleone

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

1 September 2014

1 reference

10 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

3493-3503

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

31 May 2020

copyright license

start time

1 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/onc.2014.286

0 references

cites work

IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L

1 reference

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γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer.

11 July 2018

1 reference

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IL-21 induces IL-22 production in CD4+ T cells.

11 July 2018

1 reference

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STAT3 Target Genes Relevant to Human Cancers

11 July 2018

1 reference

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Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically

11 July 2018

1 reference

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Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Early signaling events that underlie fate decisions of naive CD4(+) T cells toward distinct T-helper cell subsets

11 July 2018

1 reference

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Implications of anti-cytokine therapy in colorectal cancer and autoimmune diseases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

The dual role of inflammation in colon carcinogenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

The split nature of tumor-infiltrating leukocytes: Implications for cancer surveillance and immunotherapy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

The immune contexture in human tumours: impact on clinical outcome

11 July 2018

1 reference

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Involvement of interleukin-21 in the regulation of colitis-associated colon cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Prognostic and predictive impact of intra- and peritumoral immune infiltrates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Ablation of IL-17A abrogates progression of spontaneous intestinal tumorigenesis

11 July 2018

1 reference

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Dangerous liaisons: STAT3 and NF-kappaB collaboration and crosstalk in cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Tc17 CD8 T cells: functional plasticity and subset diversity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Worldwide variations in colorectal cancer

11 July 2018

1 reference

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Persistently activated Stat3 maintains constitutive NF-kappaB activity in tumors

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

11 July 2018

1 reference

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Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.

11 July 2018

1 reference

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Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

NF-kappaB and the immune response

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Suppression of lymphoma and epithelial malignancies effected by interferon gamma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

The risk of colorectal cancer in ulcerative colitis: a meta-analysis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Immune-inflammatory mechanisms in IFNgamma-mediated anti-tumor activity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

A novel transcription factor, T-bet, directs Th1 lineage commitment

11 July 2018

1 reference

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IFN-gamma induces cell growth inhibition by Fas-mediated apoptosis: requirement of STAT1 protein for up-regulation of Fas and FasL expression

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Enhancement of mouse natural killer cell activity by type II interferon.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

A genetic model for colorectal tumorigenesis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Role of IL-17A in the development of colitis-associated cancer.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4493653

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

24 September 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.286

Interleukin 21 controls tumour growth and tumour immunosurveillance in colitis-associated tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.286

Autocrine regulation of IL-21 production in human T lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.286

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.286

31 March 2020

Identifiers

DOI

10.1038/ONC.2014.286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25174402%20AND%20SRC:MED&resulttype=core&format=json