(Q35826926)

English

S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.

scientific article published in October 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

6-O-demethylnaproxen

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

Peter I Mackenzie

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Kushari Bowalgaha

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

David J Elliot

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Kathleen M Knights

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Stellan Swedmark

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

John O Miners

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

0 references

publication date

1 October 2005

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

60

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

423-433

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

In vitro-in vivo correlations for drugs eliminated by glucuronidation: investigations with the model substrate zidovudine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Human UDP-glucuronosyltransferases: metabolism, expression, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Nonspecific binding of drugs to human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

The pharmacokinetics of naproxen, its metabolite O-desmethylnaproxen, and their acyl glucuronides in humans. Effect of cimetidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Glucuronidation of codeine and morphine in human liver and kidney microsomes: effect of inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884820

11 July 2018

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

The effect of incubation conditions on the enzyme kinetics of udp-glucuronosyltransferases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

Effect of fluconazole on zidovudine pharmacokinetics in patients infected with human immunodeficiency virus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

Nonlinear plasma level response to high doses of naproxen

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

Evidence that unsaturated fatty acids are potent inhibitors of renal UDP-glucuronosyltransferases (UGT): kinetic studies using human kidney cortical microsomes and recombinant UGT1A9 and UGT2B7.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02446.X

21 January 2018

Pharmacokinetics of naproxen overdoses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16187975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naproxen-probenecid interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16187975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negligible excretion of unchanged ketoprofen, naproxen, and probenecid in urine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16187975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

1 reference

https://pubmed.ncbi.nlm.nih.gov/16187975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical prediction of factors influencing the elimination of 5,6-dimethylxanthenone-4-acetic acid, a new anticancer drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/16187975

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2005.02446.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16187975%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

ResearchGate publication ID

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