(Q35827839)

English

Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267.

scientific article published in April 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Safety, tolerability, and pharmacokinetic interactions of the antituberculous agent TMC207 (bedaquiline) with efavirenz in healthy volunteers: AIDS Clinical Trials Group Study A5267. (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

Susan Swindells

3

object named as

Susan Swindells

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

Kelly E Dooley

1

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Europe PubMed Central

PMC publication ID

10 August 2017

Jeong-Gun Park

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Reena Allen

4

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Europe PubMed Central

PMC publication ID

10 August 2017

David W Haas

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Yoninah Cramer

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Francesca Aweeka

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ilene Wiggins

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Amita Gupta

9

1 reference

Europe PubMed Central

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10 August 2017

Patricia Lizak

10

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Europe PubMed Central

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10 August 2017

Sonia Qasba

11

1 reference

Europe PubMed Central

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10 August 2017

Rolf van Heeswijk

12

1 reference

Europe PubMed Central

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10 August 2017

Charles Flexner

13

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Europe PubMed Central

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10 August 2017

ACTG 5267 Study Team

14

1 reference

Europe PubMed Central

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10 August 2017

language of work or name

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publication date

1 April 2012

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Europe PubMed Central

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10 August 2017

Journal of Acquired Immune Deficiency Syndromes

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Europe PubMed Central

PMC publication ID

10 August 2017

59

1 reference

Europe PubMed Central

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10 August 2017

5

1 reference

Europe PubMed Central

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10 August 2017

455-462

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Integration of antiretroviral therapy with tuberculosis treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Timing of antiretroviral therapy for HIV-1 infection and tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Earlier versus later start of antiretroviral therapy in HIV-infected adults with tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Short-course chemotherapy with TMC207 and rifapentine in a murine model of latent tuberculosis infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Activities of TMC207, rifampin, and pyrazinamide against Mycobacterium tuberculosis infection in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Bactericidal potencies of new regimens are not predictive of their sterilizing potencies in a murine model of tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

TMC207: the first compound of a new class of potent anti-tuberculosis drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Timing of initiation of antiretroviral drugs during tuberculosis therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Port-au-Prince, Haiti

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

The diarylquinoline TMC207 for multidrug-resistant tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African americans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Model-based approach to characterize efavirenz autoinduction and concurrent enzyme induction with carbamazepine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Impact of the interaction of R207910 with rifampin on the treatment of tuberculosis studied in the mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Detection of nonnucleoside reverse-transcriptase inhibitor-resistant HIV-1 after discontinuation of virologically suppressive antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Complications of antiretroviral therapy in patients with tuberculosis: drug interactions, toxicity, and immune reconstitution inflammatory syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Diarylquinolines target subunit c of mycobacterial ATP synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Synergistic activity of R207910 combined with pyrazinamide against murine tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Combinations of R207910 with drugs used to treat multidrug-resistant tuberculosis have the potential to shorten treatment duration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Drug-induced phospholipidosis: issues and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Cationic amphiphilic drug-induced phospholipidosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

11 July 2018

Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302922

24 September 2018

Identifiers

10.1097/QAI.0B013E3182410503

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

release_xitui5exjjev3nmq2e5vvs3qym

1 reference

https://api.fatcat.wiki/v0/release/xitui5exjjev3nmq2e5vvs3qym

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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