(Q35829491)

10 August 2017

Spontaneous classical pathway activation and deficiency of membrane regulators render human neurons susceptible to complement lysis (English)

1 reference

10 August 2017

S K Singhrao

1

1 reference

10 August 2017

J W Neal

2

1 reference

10 August 2017

N K Rushmere

3

1 reference

10 August 2017

B P Morgan

4

1 reference

10 August 2017

P Gasque

5

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 September 2000

1 reference

The American Journal of Pathology

10 August 2017

1 reference

10 August 2017

157

1 reference

10 August 2017

3

1 reference

10 August 2017

905-918

1 reference

The c3-activator system: an alternate pathway of complement activation.

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Induced expression of neuronal membrane attack complex and cell death by Alzheimer's beta-amyloid peptide

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Up-regulated expression of decay-accelerating factor (CD55) confers increased complement resistance to sprouting neural cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Identification of an astrocyte cell population from human brain that expresses perforin, a cytotoxic protein implicated in immune defense

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

The blood-brain barrier and the inflammatory response.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement activation on human neuroblastoma cell lines in vitro: route of activation and expression of functional complement regulatory proteins.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement activation in the central nervous system following blood-brain barrier damage in man.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

CD59 expression and complement susceptibility of human neuronal cell line (NTera2).

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Activated mouse astrocytes and T cells express similar CD44 variants. Role of CD44 in astrocyte/T cell binding

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement biosynthesis in the central nervous system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement activation by isolated myelin: activation of the classical pathway in the absence of myelin-specific antibodies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Antibody-independent complement activation by myelin via the classical complement pathway

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Primary cultures of murine astrocytes produce C3 and factor B, two components of the alternative pathway of complement activation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Molecular organization and function of the complement system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Normal rat serum cytotoxicity against syngeneic oligodendrocytes. Complement activation and attack in the absence of anti-myelin antibodies.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Oligodendrocytes and oligodendrocyte/type-2 astrocyte progenitor cells of adult rats are specifically susceptible to the lytic effects of complement in absence of antibody

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Immunocytochemical localization of the terminal complement complex in multiple sclerosis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement activation in amyloid plaques in Alzheimer's dementia.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Activation of the classical complement pathway in brain tissue of Alzheimer patients

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

CD59, an LY-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Sulfated glycoprotein-2 is increased in rat hippocampus following entorhinal cortex lesioning

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Induction of C3 expression in astrocytes is regulated by cytokines and Newcastle disease virus

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement proteins and complement inhibitors in Alzheimer's disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement activation by beta-amyloid in Alzheimer disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Expression of complement components of the alternative pathway by glioma cell lines

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Distribution of clusterin in Alzheimer brain tissue

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Control of the amplification convertase of complement by the plasma protein beta1H

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

A new function of the activated third component of complement: binding to C5, an essential step for C5 activation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Increased complement biosynthesis by microglia and complement activation on neurons in Huntington's disease

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Neuronal protection in stroke by an sLex-glycosylated complement inhibitory protein

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

24 September 2018

Complement regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Aspartate residue 7 in amyloid beta-protein is critical for classical complement pathway activation: implications for Alzheimer's disease pathogenesis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Activation of the complement cascade and increase of clusterin in the brain following a cortical contusion in the adult rat.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

CD44 expression in human astrocytes and oligodendrocytes in culture.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Complement-mediated neurotoxicity is regulated by homologous restriction.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Immunoglobulins and complement factors in senile plaques. An immunoperoxidase study.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885712

Initiation of complement activation

24 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Expression of the complement membrane attack complex and its inhibitors in Pick disease brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Role of complement in the aetiology of Pick's disease?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Human astrocytes express membrane cofactor protein (CD46), a regulator of complement activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

The expression of complement regulatory proteins by adult human oligodendrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Vesicular removal by oligodendrocytes of membrane attack complexes formed by activated complement

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Killing of rat glial cells by complement: deficiency of the rat analogue of CD59 is the cause of oligodendrocyte susceptibility to lysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Preferential inactivation of the C5 convertase of the alternative complement pathway by factor I and membrane cofactor protein (MCP)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

Control of C3b and C5b deposition by CD46 (membrane cofactor protein) after alternative but not classical complement activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964604-4

The expression of CD59 in normal human nervous tissue

7 January 2021

1 reference

12 December 2020

Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes

1 reference

12 December 2020

Differential expression of individual complement regulators in the brain and choroid plexus

1 reference

12 December 2020

Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysis

1 reference

12 December 2020

Soluble recombinant complement receptor 1 inhibits inflammation and demyelination in antibody-mediated demyelinating experimental allergic encephalomyelitis

1 reference

12 December 2020

Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines

1 reference

12 December 2020

Human oligodendrocytes are not sensitive to complement. A study of CD59 expression in the human central nervous system

1 reference

12 December 2020

10.1016/S0002-9440(10)64604-4

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

10980130

1 reference