(Q35830845)

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Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases.

scientific article published on 15 February 2012

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scholarly article

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20 January 2020

Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases (English)

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20 January 2020

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Joanna A Ruszkiewicz

4

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20 January 2020

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20 January 2020

Michael Aschner

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Michael Aschner

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20 January 2020

Dejan Milatovic

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Dejan Milatovic

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20 January 2020

Magdalena Zielińska

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Magdalena Zielińska

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20 January 2020

Marta Skowrońska

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Marta Skowrońska

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20 January 2020

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Luiza Wójcik-Stanaszek

3

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20 January 2020

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15 February 2012

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20 January 2020

Journal of Neurochemistry

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20 January 2020

121

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20 January 2020

1

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20 January 2020

125-134

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20 January 2020

Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease

1 reference

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Assessments of tight junction proteins occludin, claudin 5 and scaffold proteins ZO1 and ZO2 in endothelial cells of the rat blood-brain barrier: cellular responses to neurotoxicants malathion and lead acetate.

1 reference

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Stimulation of natriuretic peptide receptor C attenuates accumulation of reactive oxygen species and nitric oxide synthesis in ammonia-treated astrocytes

1 reference

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Direct exposure to ammonia and hyperammonemia increase the extracellular accumulation and degradation of astroglia-derived glutathione in the rat prefrontal cortex

1 reference

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Brain edema dynamics in patients with overt hepatic encephalopathy A magnetic resonance imaging study.

1 reference

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Interaction of oxidative stress, astrocyte swelling and cerebral ammonia toxicity

1 reference

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Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure

1 reference

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Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

1 reference

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27 July 2018

Signaling factors in the mechanism of ammonia neurotoxicity

1 reference

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27 July 2018

NFkappaB in the mechanism of ammonia-induced astrocyte swelling in culture

1 reference

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27 July 2018

Ammonia inhibits the C-type natriuretic peptide-dependent cyclic GMP synthesis and calcium accumulation in a rat brain endothelial cell line

1 reference

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Mechanisms of brain edema in acute liver failure and impact of novel therapeutic interventions.

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F2-isoprostanes are not just markers of oxidative stress

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27 July 2018

Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro

1 reference

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27 July 2018

Amino acids as modulators of endothelium-derived nitric oxide

1 reference

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27 July 2018

Matrix metalloproteinase-9 contributes to brain extravasation and edema in fulminant hepatic failure mice

1 reference

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27 July 2018

Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy

1 reference

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27 July 2018

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine

1 reference

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27 July 2018

Transendothelial permeability changes induced by free radicals in an in vitro model of the blood-brain barrier

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Glutathione measurement by high-performance liquid chromatography separation and fluorometric detection of the glutathione-orthophthalaldehyde adduct

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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27 July 2018

Oxidative stress and blood-brain barrier dysfunction under particular consideration of matrix metalloproteinases.

1 reference

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24 September 2018

Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats.

1 reference

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Caffeine induces matrix metalloproteinase-2 (MMP-2) and MMP-9 down-regulation in human leukemia U937 cells via Ca2+/ROS-mediated suppression of ERK/c-fos pathway and activation of p38 MAPK/c-jun pathway

1 reference

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24 September 2018

Hyperammonemia induces neuroinflammation that contributes to cognitive impairment in rats with hepatic encephalopathy

1 reference

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Blood-brain barrier permeability for ammonia in patients with different grades of liver fibrosis is not different from healthy controls.

1 reference

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Oxidative stress and apoptosis of human brain microvascular endothelial cells induced by free fatty acids.

1 reference

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L-ornithine and phenylacetate synergistically produce sustained reduction in ammonia and brain water in cirrhotic rats

1 reference

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24 September 2018

Manganese induces oxidative impairment in cultured rat astrocytes.

1 reference

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24 September 2018

Fulminant hepatic failure in rats induces oxidative stress differentially in cerebral cortex, cerebellum and pons medulla.

1 reference

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Mechanisms of ammonia-induced cell death in rat cortical neurons: roles of NMDA receptors and glutathione.

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Hyperammonemia increases the expression and activity of the glutamine/arginine transporter y+LAT2 in rat cerebral cortex: Implications for the nitric oxide/cGMP pathway

1 reference

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1 reference

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12 December 2020

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Identifiers

10.1111/J.1471-4159.2012.07669.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260250%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260250%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22260250%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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