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English
Erythropoietin as an antiapoptotic, tissue-protective cytokine.
scientific article published in July 2004
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Erythropoietin as an antiapoptotic, tissue-protective cytokine
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
main subject
erythropoietin
1 reference
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inferred from title
author
Pietro Ghezzi
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
Michael Brines
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
author name string
Ghezzi P
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
retrieved
10 August 2017
Brines M
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
retrieved
10 August 2017
publication date
1 July 2004
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
published in
Cell Death & Differentiation
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
volume
11 Suppl 1
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
page(s)
S37-44
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401450
0 references
cites work
HIF-1 and mechanisms of hypoxia sensing
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Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression
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Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.
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Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]
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VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death
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Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.
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VEGF-induced neuroprotection, neurogenesis, and angiogenesis after focal cerebral ischemia
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Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
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Crossref
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Erythropoietin: a candidate compound for neuroprotection in schizophrenia
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7 January 2021
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Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
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Crossref
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7 January 2021
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inferred from DOI database lookup
Maintenance by erythropoietin of viability and maturation of murine erythroid precursor cells
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
A novel family of growth factor receptors: a common binding domain in the growth hormone, prolactin, erythropoietin and IL-6 receptors, and the p75 IL-2 receptor beta-chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
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inferred from DOI database lookup
Structural design and molecular evolution of a cytokine receptor superfamily
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Signal transduction in the erythropoietin receptor system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
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inferred from DOI database lookup
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin can induce the expression of bcl-x(L) through Stat5 in erythropoietin-dependent progenitor cell lines
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction
1 reference
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Crossref
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7 January 2021
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Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia
1 reference
stated in
Crossref
reference URL
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Role of PI3-kinase in Bcl-X induction and apoptosis inhibition mediated by IL-3 or IGF-1 in Baf-3 cells
1 reference
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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
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7 January 2021
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inferred from DOI database lookup
A potential role for erythropoietin in focal permanent cerebral ischemia in mice.
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Increased expression of erythropoietin receptor on blood vessels in the human epileptogenic hippocampus with sclerosis
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Erythropoietin and erythropoietin receptor in human ischemic/hypoxic brain.
1 reference
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Crossref
reference URL
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inferred from DOI database lookup
Erythropoietin and erythropoietin receptors in human CNS neurons, astrocytes, microglia, and oligodendrocytes grown in culture
1 reference
stated in
Crossref
reference URL
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Erythropoietin protects cultured cortical neurons, but not astroglia, from hypoxia and AMPA toxicity
1 reference
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Crossref
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7 January 2021
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Immunohistochemical localization of erythropoietin and its receptor in the developing human brain.
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Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality
1 reference
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Crossref
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inferred from DOI database lookup
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
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7 January 2021
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inferred from DOI database lookup
Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: termination of CNS autoimmune inflammation and modulation by interferon-beta
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Apoptotic PC12 cells exposing phosphatidylserine promote the production of anti-inflammatory and neuroprotective molecules by microglial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
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7 January 2021
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inferred from DOI database lookup
Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glia increase degeneration of hippocampal neurons through release of tumor necrosis factor-alpha.
1 reference
stated in
Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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7 January 2021
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1 reference
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Crossref
reference URL
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7 January 2021
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1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Lysophosphatidic acid prevents renal ischemia-reperfusion injury by inhibition of apoptosis and complement activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin inhibits calcium-induced neurotransmitter release from clonal neuronal cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
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inferred from DOI database lookup
Erythropoietin improves place learning in fimbria-fornix-transected rats and modifies the search pattern of normal rats.
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of erythropoietin on glial cell development; oligodendrocyte maturation and astrocyte proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin protects neurons against chemical hypoxia and cerebral ischemic injury by up-regulating Bcl-xL expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin induces changes in gene expression in PC-12 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin protects the developing brain against N-methyl-D-aspartate receptor antagonist neurotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ISSLS prize winner: Erythropoietin inhibits spinal neuronal apoptosis and pain following nerve root crush
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin protects the in vitro blood-brain barrier against VEGF-induced permeability.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin protects against ischaemic acute renal injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preconditioning with erythropoietin protects against subsequent ischemia-reperfusion injury in rat kidney
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin enhances recovery after cisplatin-induced acute renal failure in the rat.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant human erythropoietin influences revascularization and healing in a rat model of random ischaemic flaps.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of chronic and short-term erythropoietin treatment on random flap survival in rats: an experimental study.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin and VEGF exhibit equal angiogenic potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin therapy for acute stroke is both safe and beneficial
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of erythropoietin on neuronal activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo evidence that erythropoietin protects neurons from ischemic damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroprotective effect of erythropoietin on hypoxic-ischemic brain injury in neonatal rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential neuroprotective benefits of erythropoietin during experimental hypothermic circulatory arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin exerts neuroprotection in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/BL mice via increasing nitric oxide production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Erythropoietin both protects from and reverses experimental diabetic neuropathy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of recombinant human erythropoietin in lipid peroxidation and platelet-activating factor generation in a rat model of necrotizing enterocolitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4401450
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4401450
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
PubMed ID
15243580
1 reference
stated in
Europe PubMed Central
PubMed ID
15243580
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243580%20AND%20SRC:MED&resulttype=core&format=json
retrieved
30 December 2019
ResearchGate publication ID
8464839
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