(Q35831223)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

review article

1 reference

title

Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Austin RC

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Werstuck GH

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

1 reference

1 July 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

11 Suppl 1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

S56-64

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401451

30 December 2019

exact match

0 references

cites work

Atherosclerosis — An Inflammatory Disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Atherosclerosis: basic mechanisms. Oxidation, inflammation, and genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

21 January 2018

The unstable atheroma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Apoptosis of vascular smooth muscle cells in vascular remodelling and atherosclerotic plaque rupture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Hyperhomocysteinemia as a risk factor for deep-vein thrombosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine induces programmed cell death in human vascular endothelial cells through activation of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Effects of homocysteine on proliferation, necrosis, and apoptosis of vascular smooth muscle cells in culture and influence of folic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Hyperhomocysteinemia, oxidative stress, and cerebral vascular dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-alpha, NAD(P)H oxidase, and inducible nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Characterization of the stress-inducing effects of homocysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine induces expression and secretion of monocyte chemoattractant protein-1 and interleukin-8 in human aortic endothelial cells: implications for vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Is homocysteine a pro-oxidant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Redox regulation of homocysteine-dependent glutathione synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

The quantitatively important relationship between homocysteine metabolism and glutathione synthesis by the transsulfuration pathway and its regulation by redox changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Translational control in the endoplasmic reticulum stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

The glucose-regulated proteins: stress induction and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Orchestrating the unfolded protein response in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

A trip to the ER: coping with stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Hyperhomocysteinemia and its role in the development of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Taurine prevents the decrease in expression and secretion of extracellular superoxide dismutase induced by homocysteine: amelioration of homocysteine-induced endoplasmic reticulum stress by taurine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine thiolactone induces apoptotic DNA damage mediated by increased intracellular hydrogen peroxide and caspase 3 activation in HL-60 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine induces endothelial cell detachment and vessel wall thickening during chick embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Homocysteine induces trophoblast cell death with apoptotic features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Metabolism of homocysteine, its relation to the other cellular thiols and its mechanism of cell damage in a cell culture line (human histiocytic cell line U-937).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

A novel pleckstrin homology-related gene family defined by Ipl/Tssc3, TDAG51, and Tih1: tissue-specific expression, chromosomal location, and parental imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide-protein co-operative mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Dissection of the Drosophila paired protein: functional requirements for conserved motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

A proline- and glutamine-rich protein promotes apoptosis in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Inhibition of protein synthesis and early protein processing by thapsigargin in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Effects of folate supplementation in hyperhomocysteinemic pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Consequences of hyperhomocyst(e)inemia on vascular function in atherosclerotic monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Supplementation of atherogenic diet with B vitamins does not prevent atherosclerosis or vascular dysfunction in monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Tissue factor modulates the thrombogenicity of human atherosclerotic plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

Reverse cholesterol transport and atherosclerosis regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

A definition of initial, fatty streak, and intermediate lesions of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Apoptosis in human atherosclerosis and restenosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Distribution of cell replication and apoptosis in atherosclerotic plaques of cholesterol-fed rabbits

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Foam cell apoptosis and the development of the lipid core of human atherosclerosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Hyperhomocysteinemia: an independent risk factor for vascular disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocysteine and vascular disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

The controversy over homocysteine and cardiovascular risk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocysteine and atherothrombosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Treatment of mild hyperhomocysteinemia in vascular disease patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Vitamin status and intake as primary determinants of homocysteinemia in an elderly population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Inhibition of growth and p21ras methylation in vascular endothelial cells by homocysteine but not cysteine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocysteine induces monocyte chemoattractant protein-1 expression by activating NF-kappaB in THP-1 macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Hyperhomocysteinemia and oxidative stress: time for a reality check?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocysteine-induced inhibition of endothelium-dependent relaxation in rabbit aorta: role for superoxide anions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving glutathione peroxidase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Adenovirus-mediated heme oxygenase-1 gene transfer inhibits the development of atherosclerosis in apolipoprotein E-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Analysis of the UL36 open reading frame encoding the large tegument protein (ICP1/2) of herpes simplex virus type 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine beta-synthase-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocysteine as a risk factor for vascular disease. Enhanced collagen production and accumulation by smooth muscle cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Tissue-factor antigen and activity in human coronary atherosclerotic plaques

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401451

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401451

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15243582%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference