(Q35837172)

English

HIV-1 Vpr Protein Enhances Proteasomal Degradation of MCM10 DNA Replication Factor through the Cul4-DDB1[VprBP] E3 Ubiquitin Ligase to Induce G2/M Cell Cycle Arrest.

scientific article published in June 2015

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26032416%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

HIV-1 Vpr Protein Enhances Proteasomal Degradation of MCM10 DNA Replication Factor through the Cul4-DDB1[VprBP] E3 Ubiquitin Ligase to Induce G2/M Cell Cycle Arrest (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26032416%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Mohammad Reze Aghasadeghi

3

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16 February 2020

author name string

Bizhan Romani

1

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16 February 2020

Nima Shaykh Baygloo

2

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16 February 2020

Elham Allahbakhshi

4

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16 February 2020

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1 June 2015

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16 February 2020

Journal of Biological Chemistry

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16 February 2020

290

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16 February 2020

28

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16 February 2020

17380-17389

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16 February 2020

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11 June 2022

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Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing

1 reference

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27 July 2018

The HIV-1 protein Vpr targets the endoribonuclease Dicer for proteasomal degradation to boost macrophage infection

1 reference

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27 July 2018

HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex

1 reference

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27 July 2018

Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation

1 reference

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27 July 2018

CRL4-DDB1-VPRBP ubiquitin ligase mediates the stress triggered proteolysis of Mcm10.

1 reference

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27 July 2018

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

1 reference

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27 July 2018

The HIV1 protein Vpr acts to enhance constitutive DCAF1-dependent UNG2 turnover

1 reference

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27 July 2018

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

1 reference

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SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

1 reference

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27 July 2018

Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif.

1 reference

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27 July 2018

HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

1 reference

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27 July 2018

Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

1 reference

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27 July 2018

Centromeric protein CENP-B proteasomal degradation induced by the viral protein ICP0.

1 reference

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27 July 2018

A conserved Hsp10-like domain in Mcm10 is required to stabilize the catalytic subunit of DNA polymerase-alpha in budding yeast.

1 reference

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27 July 2018

Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1

1 reference

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27 July 2018

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

1 reference

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27 July 2018

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

1 reference

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27 July 2018

Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45.

1 reference

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27 July 2018

Degradation of nucleosome-associated centromeric histone H3-like protein CENP-A induced by herpes simplex virus type 1 protein ICP0

1 reference

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27 July 2018

Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.

1 reference

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27 July 2018

A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae

1 reference

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27 July 2018

HSV-1 ICP0: paving the way for viral replication

1 reference

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24 September 2018

Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection

1 reference

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24 September 2018

The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4498075

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Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha.

1 reference

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Viruses and the 26S proteasome: hacking into destruction

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Identifiers

10.1074/JBC.M115.641522

1 reference

Europe PubMed Central

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16 February 2020

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Europe PubMed Central

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16 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26032416%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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