(Q37520106)

20 August 2017

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title

Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection (English)

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20 August 2017

protein ubiquitination

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2

Hidde L Ploegh

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20 August 2017

Marisa K Isaacson

1

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20 August 2017

1 June 2009

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20 August 2017

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20 August 2017

5

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20 August 2017

559-570

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20 August 2017

6

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Downregulation of major histocompatibility complex class I molecules by Kaposi's sarcoma-associated herpesvirus K3 and K5 proteins

20 August 2017

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12 December 2020

Kaposi's sarcoma-associated herpesvirus RTA promotes degradation of the Hey1 repressor protein through the ubiquitin proteasome pathway

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12 December 2020

A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.

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12 December 2020

Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes

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12 December 2020

Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases

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12 December 2020

Interferon-inducible antiviral effectors

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12 December 2020

The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta

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12 December 2020

Immunoregulatory properties of ISG15, an interferon-induced cytokine

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12 December 2020

A viral protein that selectively downregulates ICAM-1 and B7-2 and modulates T cell costimulation

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12 December 2020

Herpes virus induced proteasome-dependent degradation of the nuclear bodies-associated PML and Sp100 proteins

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12 December 2020

Regulation of receptors and transporters by ubiquitination: new insights into surprisingly similar mechanisms

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12 December 2020

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.

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12 December 2020

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

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12 December 2020

Kaposi's sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis

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12 December 2020

The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53.

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12 December 2020

USP11 stabilizes HPV-16E7 and further modulates the E7 biological activity

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12 December 2020

Identification of interferon-stimulated gene 15 as an antiviral molecule during Sindbis virus infection in vivo

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12 December 2020

Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

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12 December 2020

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12 December 2020

Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase

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12 December 2020

Manipulation of the ubiquitin-proteasome pathway by small DNA tumor viruses

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12 December 2020

Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo

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12 December 2020

High-risk but not low-risk HPV E2 proteins bind to the APC activators Cdh1 and Cdc20 and cause genomic instability

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12 December 2020

Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha

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12 December 2020

SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting

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12 December 2020

The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes

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12 December 2020

SOCS1 [corrected] inhibits HPV-E7-mediated transformation by inducing degradation of E7 protein

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12 December 2020

The role of ubiquitin in retroviral egress

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12 December 2020

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

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12 December 2020

Simian virus 5 V protein acts as an adaptor, linking DDB1 to STAT2, to facilitate the ubiquitination of STAT1

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12 December 2020

ISG15 inhibits Nedd4 ubiquitin E3 activity and enhances the innate antiviral response

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12 December 2020

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12 December 2020

HIV-1 reverse transcription initiation: a potential target for novel antivirals?

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12 December 2020

HAUSP/USP7 as an Epstein-Barr virus target

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12 December 2020

Epstein-Barr virus associated modulation of Wnt pathway is not dependent on latent membrane protein-1.

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12 December 2020

STAT-1- and IRF-3-dependent pathways are not essential for repression of ICP0-null mutant herpes simplex virus type 1 in human fibroblasts

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12 December 2020

Structural aspects of recently discovered viral deubiquitinating activities

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12 December 2020

Human papilloma virus (HPV) and host cellular interactions

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12 December 2020

Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15.

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12 December 2020

Urm1 at the crossroad of modifications. 'Protein Modifications: Beyond the Usual Suspects' Review Series

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12 December 2020

Deubiquitinating function of adenovirus proteinase

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12 December 2020

ISG15, an interferon-stimulated ubiquitin-like protein, is not essential for STAT1 signaling and responses against vesicular stomatitis and lymphocytic choriomeningitis virus

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12 December 2020

Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

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12 December 2020

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

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12 December 2020

Modification of proteins by ubiquitin and ubiquitin-like proteins

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12 December 2020

High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: mutant viruses altered in its active-site cysteine or histidine are viable

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12 December 2020

Epstein-barr virus encodes three bona fide ubiquitin-specific proteases

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12 December 2020

Role of tRNA-like structures in controlling plant virus replication

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12 December 2020

Epstein-Barr virus nuclear antigen 3C putative repression domain mediates coactivation of the LMP1 promoter with EBNA-2.

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12 December 2020

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

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12 December 2020

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

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12 December 2020

Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular components.

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12 December 2020

SUMO-1 modification required for transformation by adenovirus type 5 early region 1B 55-kDa oncoprotein

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12 December 2020

A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway

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12 December 2020

MHC class I ubiquitination by a viral PHD/LAP finger protein.

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12 December 2020

Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1

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12 December 2020

The Epstein-Barr virus (EBV) deubiquitinating enzyme BPLF1 reduces EBV ribonucleotide reductase activity.

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12 December 2020

A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7

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12 December 2020

HIV-1 Vif, APOBEC, and intrinsic immunity

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12 December 2020

Effects of SUMO-1 upon Epstein-Barr virus BZLF1 function and BMRF1 expression

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12 December 2020

Mechanisms underlying ubiquitination

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12 December 2020

Selectivity in ISG15 and ubiquitin recognition by the SARS coronavirus papain-like protease

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12 December 2020

A genomic and functional inventory of deubiquitinating enzymes

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12 December 2020

Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b

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12 December 2020

Identification of the structural and functional human homolog of the yeast ubiquitin conjugating enzyme UBC9

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12 December 2020

Controlling receptor downregulation by ubiquitination and deubiquitination

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12 December 2020

Regulated degradation of the HIV-1 Vpu protein through a betaTrCP-independent pathway limits the release of viral particles

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12 December 2020

African swine fever virus protease, a new viral member of the SUMO-1-specific protease family

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12 December 2020

Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions

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12 December 2020

Role of HIV-1 Vpu protein for virus spread and pathogenesis

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12 December 2020

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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12 December 2020

Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection

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12 December 2020

The papillomavirus E7 oncoprotein is ubiquitinated by UbcH7 and Cullin 1- and Skp2-containing E3 ligase

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12 December 2020

HPV16 E5 protein disrupts the c-Cbl-EGFR interaction and EGFR ubiquitination in human foreskin keratinocytes

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12 December 2020

The Epstein-Barr virus latent membrane protein 2A PY motif recruits WW domain-containing ubiquitin-protein ligases

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12 December 2020

ISG15 enhances the innate antiviral response by inhibition of IRF-3 degradation.

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12 December 2020

The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.

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12 December 2020

Substrate specificity of adenovirus protease

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12 December 2020

STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signaling

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12 December 2020

Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

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12 December 2020

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

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12 December 2020

Herpes simplex virus 1-infected cell protein 0 contains two E3 ubiquitin ligase sites specific for different E2 ubiquitin-conjugating enzymes

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12 December 2020

Overexpression of the N-terminal domain of TSG101 inhibits HIV-1 budding by blocking late domain function

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12 December 2020

Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p

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12 December 2020

A protein conjugation system in yeast with homology to biosynthetic enzyme reaction of prokaryotes

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12 December 2020

Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor

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12 December 2020

A new protease required for cell-cycle progression in yeast

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12 December 2020

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

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12 December 2020

Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein

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12 December 2020

The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation

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12 December 2020

Ability of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cells

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12 December 2020

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

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12 December 2020

Nedd4 regulates egress of Ebola virus-like particles from host cells

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12 December 2020

HPV E6, E6AP and cervical cancer

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12 December 2020

Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex

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12 December 2020

Wnt signalling in stem cells and cancer

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12 December 2020

Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

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12 December 2020

Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex

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12 December 2020

Non-covalent interaction between nucleocapsid protein of Tula hantavirus and small ubiquitin-related modifier-1, SUMO-1.

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12 December 2020

ISG15 inhibits Ebola VP40 VLP budding in an L-domain-dependent manner by blocking Nedd4 ligase activity

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12 December 2020

A deubiquitinating activity is conserved in the large tegument protein of the herpesviridae

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12 December 2020

The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol

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12 December 2020

A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae

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12 December 2020

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

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12 December 2020

Kaposi's sarcoma-associated herpesvirus transactivator RTA promotes degradation of the repressors to regulate viral lytic replication

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12 December 2020

Ubiquitylation in innate and adaptive immunity.

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12 December 2020

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

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12 December 2020

Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitro

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12 December 2020

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

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12 December 2020

A role for ubiquitin ligase recruitment in retrovirus release

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12 December 2020

Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20.

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12 December 2020

Stability of the human papillomavirus type 18 E2 protein is regulated by a proteasome degradation pathway through its amino-terminal transactivation domain

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12 December 2020

The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme

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12 December 2020

Mason–Pfizer monkey virus Gag proteins interact with the human sumo conjugating enzyme, hUbc9

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12 December 2020

Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions.

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12 December 2020

10.1016/J.CHOM.2009.05.012

Identifiers

DOI

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20 August 2017

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PubMed ID

19527883