(Q35838973)

English

Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice

scientific article published on 9 January 2012

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scholarly article

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Europe PubMed Central

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20 January 2020

Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice (English)

1 reference

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20 January 2020

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20 January 2020

author name string

Margaret Czesak

1

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20 January 2020

Brice Le François

2

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20 January 2020

Anne M Millar

3

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20 January 2020

Mariam Deria

4

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20 January 2020

Mireille Daigle

5

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20 January 2020

Jane E Visvader

6

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20 January 2020

Hymie Anisman

7

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20 January 2020

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publication date

9 January 2012

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20 January 2020

number of pages

13

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Journal of Biological Chemistry

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20 January 2020

287

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20 January 2020

9

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20 January 2020

6615-6627

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20 January 2020

Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety

1 reference

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27 July 2018

Pet-1 is required across different stages of life to regulate serotonergic function.

1 reference

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27 July 2018

Higher serotonin 1A binding in a second major depression cohort: modeling and reference region considerations

1 reference

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27 July 2018

Early response to selective serotonin reuptake inhibitors in panic disorder is associated with a functional 5-HT1A receptor gene polymorphism

1 reference

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27 July 2018

Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization

1 reference

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27 July 2018

Positron emission tomography quantification of serotonin-1A receptor binding in medication-free bipolar depression

1 reference

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27 July 2018

Functional coding variation in recombinant inbred mouse lines reveals multiple serotonin transporter-associated phenotypes.

1 reference

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27 July 2018

Transcriptional regulation at a HTR1A polymorphism associated with mental illness.

1 reference

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27 July 2018

Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder.

1 reference

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27 July 2018

Redefining the serotonergic system by genetic lineage

1 reference

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27 July 2018

Serotonin-1A receptor imaging in recurrent depression: replication and literature review

1 reference

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27 July 2018

Characterization of rat rostral raphe primary cultures: multiplex quantification of serotonergic markers

1 reference

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27 July 2018

Serotonergic vulnerability and depression: assumptions, experimental evidence and implications.

1 reference

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27 July 2018

Cell-specific repressor or enhancer activities of Deaf-1 at a serotonin 1A receptor gene polymorphism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Higher 5-HT1A receptor binding potential during a major depressive episode predicts poor treatment response: preliminary data from a naturalistic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder.

1 reference

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27 July 2018

Altered serotonin 1A binding in major depression: a [carbonyl-C-11]WAY100635 positron emission tomography study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Cell type-dependent recruitment of trichostatin A-sensitive repression of the human 5-HT1A receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

The pharmacology of putative early-onset antidepressant strategies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Differential regulation of 5-HT1A receptor-G protein interactions in brain following chronic antidepressant administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Differential adaptation of brain 5-HT1A and 5-HT1B receptors and 5-HT transporter in rats treated chronically with fluoxetine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Brain Serotonin1A Receptor Binding Measured by Positron Emission Tomography With [11C]WAY-100635

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Role of the serotonergic system in the pathogenesis of major depression and suicidal behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Increased anxiety of mice lacking the serotonin1A receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

A.E. Bennett Research Award. Regulation of serotonin1A, glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: implications for the neurobiology of depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Serotonin-specific drugs for anxiety and depressive disorders

1 reference

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27 July 2018

Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain — a combined in situ hybridisation/in vitro receptor autoradiographic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

27 July 2018

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Reduced anxiety-related behaviour in transgenic mice overexpressing serotonin 1A receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Phosphorylation of Ser19 increases both Ser40 phosphorylation and enzyme activity of tyrosine hydroxylase in intact cells.

1 reference

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21 January 2018

Novel dual repressor elements for neuronal cell-specific transcription of the rat 5-HT1A receptor gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Serotonin 1A receptor gene and major depressive disorder: an association study and meta-analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

A cell-autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration.

1 reference

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21 January 2018

DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Tryptophan hydroxylase-2 controls brain serotonin synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Region-specific regulation of 5-HT1A receptor expression by Pet-1-dependent mechanisms in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Differential effects of 5-HT1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Modification of serotonin neuron properties in mice lacking 5-HT1A receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

HES1 regulates 5-HT1A receptor gene transcription at a functional polymorphism: essential role in developmental expression.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT1A receptors in rat brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Antagonist-induced increase in 5-HT1A-receptor expression in adult rat hippocampus and cortex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Behavioral depression and positron emission tomography-determined serotonin 1A receptor binding potential in cynomolgus monkeys.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.293027

21 January 2018

Evidence for a combined genetic effect of the 5-HT(1A) receptor and serotonin transporter genes in the clinical outcome of major depressive patients treated with citalopram

1 reference

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21 January 2018

Serotonin receptor 1A-1019C/G variant: impact on antidepressant pharmacoresponse in melancholic depression?

1 reference

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21 January 2018

The --1019 C/G polymorphism of the 5-HT(1)A receptor gene is associated with negative symptom response to risperidone treatment in schizophrenia patients.

1 reference

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21 January 2018

Association study of two serotonin 1A receptor gene polymorphisms and fluoxetine treatment response in Chinese major depressive disorders

1 reference

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21 January 2018

Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide

1 reference

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24 September 2018

Autoregulation of serotonin neurons: role in antidepressant drug action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

24 September 2018

Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression-postmortem evidence for decreased serotonin activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

24 September 2018

Electrophysiological characterization of the effect of long-term duloxetine administration on the rat serotonergic and noradrenergic systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307310

24 September 2018

Identifiers

10.1074/JBC.M111.293027

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232550%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232550%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232550%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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