(Q35841816)

10 August 2017

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title

Treatment of type 1 diabetes with anti-T-cell agents: from T-cell depletion to T-cell regulation (English)

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10 August 2017

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2

Kevan C Herold

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10 August 2017

Mariela Glandt

1

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10 August 2017

publication date

1 August 2004

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10 August 2017

published in

Current diabetes report

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10 August 2017

volume

4

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10 August 2017

issue

4

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10 August 2017

page(s)

291-297

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Induction of tolerance by monoclonal antibody therapy

10 August 2017

cites work

1 reference

12 December 2020

T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice

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12 December 2020

Treatment with anti-T-lymphocyte antibodies prevents induction of insulitis in mice given multiple doses of streptozocin

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12 December 2020

Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes

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Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

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12 December 2020

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

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12 December 2020

Induction of tolerance in peripheral T cells with monoclonal antibodies.

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12 December 2020

Experience with a chimeric monoclonal anti-CD4 antibody in the treatment of refractory rheumatoid arthritis

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12 December 2020

Humanized, nonmitogenic OKT3 antibody, huOKT3 gamma(Ala-Ala): initial clinical experience

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12 December 2020

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

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12 December 2020

In vivo use of OKT3: main issues for the monitoring of treated patients

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12 December 2020

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

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12 December 2020

Immunosuppression with azathioprine and prednisone in recent-onset insulin-dependent diabetes mellitus

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12 December 2020

Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential

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12 December 2020

T helper cell subsets in insulin-dependent diabetes

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12 December 2020

In vivo cell activation following OKT3 administration. Systemic cytokine release and modulation by corticosteroids

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12 December 2020

Anti-thymocyte globulin and prednisone immunotherapy of recent onset type 1 diabetes mellitus.

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12 December 2020

Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms

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12 December 2020

Anti-CD3 F(ab')2 fragments are immunosuppressive in vivo without evoking either the strong humoral response or morbidity associated with whole mAb

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12 December 2020

The anti-CD3-induced syndrome: a consequence of massive in vivo cell activation

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12 December 2020

Advantages of F(ab')2 fragments of anti-CD3 monoclonal antibody as compared to whole antibody as immunosuppressive agents in mice

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12 December 2020

Inhibition of an in vitro CD4+ T cell alloresponse using altered peptide ligands

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12 December 2020

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

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12 December 2020

"Infectious" transplantation tolerance.

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12 December 2020

Pharmacokinetic, pharmacodynamic and clinical effects of a humanized IgG1 anti-CD4 monoclonal antibody in the peripheral blood and synovial fluid of rheumatoid arthritis patients

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12 December 2020

Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes.

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12 December 2020

Cyclosporin prevents diabetes in BB Wistar rats

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12 December 2020

Development of type 1 diabetes despite severe hereditary B-cell deficiency

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12 December 2020

Preventive effects of cyclosporin on diabetes in NOD mice

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12 December 2020

The use of monoclonal antibodies for treatment of autoimmune disease

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12 December 2020

Effects of Cyclosporine Immunosuppression in Insulin-Dependent Diabetes Mellitus of Recent Onset

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12 December 2020

Modified anti-CD3 therapy in psoriatic arthritis: a phase I/II clinical trial

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12 December 2020

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

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12 December 2020

Factors associated with early remission of type I diabetes in children treated with cyclosporine

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12 December 2020

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

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12 December 2020

Achieving antigen-specific immune regulation

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12 December 2020

Tolerance induction in the adult using monoclonal antibodies to CD4, CD8, and CD11a (LFA-1)

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12 December 2020

CD4 coating, but not CD4 depletion, is a predictor of efficacy with primatized monoclonal anti-CD4 treatment of active rheumatoid arthritis.

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12 December 2020

Following a diabetogenic T cell from genesis through pathogenesis

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12 December 2020

Prevention of autoimmune diabetes with nonactivating anti-CD3 monoclonal antibody

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12 December 2020

Chimeric CD4 monoclonal antibody cM-T412 as a therapeutic approach to rheumatoid arthritis

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12 December 2020

Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

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12 December 2020

Nonmitogenic anti-CD3 monoclonal antibodies deliver a partial T cell receptor signal and induce clonal anergy

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12 December 2020

Subsets of CD4+T Cells and their Roles in the Induction and Prevention of Autoimmunity

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12 December 2020

Identification of a monoclonal antibody specific for a murine T3 polypeptide

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12 December 2020

In vitro characterization of five humanized OKT3 effector function variant antibodies.

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12 December 2020

The kidney in cyclosporin A-treated diabetic patients: a long-term clinicopathological study

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12 December 2020

Mechanisms in CD4 antibody-mediated transplantation tolerance: kinetics of induction, antigen dependency and role of regulatory T cells.

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12 December 2020

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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12 December 2020

Cyclosporine in recent onset type I diabetes mellitus. Effects on islet beta cell function. Miami Cyclosporine Diabetes Study Group

1 reference

12 December 2020

Regulating the immune response to transplants. a role for CD4+ regulatory cells?

1 reference

12 December 2020

How do monoclonal antibodies induce tolerance? A role for infectious tolerance?

1 reference

12 December 2020

CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

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12 December 2020

Spontaneous diabetes mellitus in the BB/W rat. Effects of glucocorticoids, cyclosporin-A, and antiserum to rat lymphocytes

1 reference

12 December 2020

Partial TCR signals delivered by FcR-nonbinding anti-CD3 monoclonal antibodies differentially regulate individual Th subsets

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12 December 2020

Prevention of diabetes mellitus in the BB/W rat with Cyclosporin-A

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12 December 2020

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

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12 December 2020

Anti-CD4 treatment of patients with rheumatoid arthritis. Is there still a place for this treatment principle in RA?

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12 December 2020

Effects of in vivo administration of anti-T3 monoclonal antibody on T cell function in mice. I. Immunosuppression of transplantation responses

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12 December 2020

Clinical and immunologic effects of a PRIMATIZED anti-CD4 monoclonal antibody in active rheumatoid arthritis: results of a phase I, single dose, dose escalating trial.

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12 December 2020

Passive transfer of diabetes in the BB/W rat

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12 December 2020

Repeat-cycle study of high-dose intravenous 4162W94 anti-CD4 humanized monoclonal antibody in rheumatoid arthritis. A randomized placebo-controlled trial

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12 December 2020

Effects of in vivo administration of anti-CD3 monoclonal antibody on T cell function in mice. II. In vivo activation of T cells

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12 December 2020

Effects of an anti-CD5 immunoconjugate (CD5-plus) in recent onset type I diabetes mellitus: a preliminary investigation. The CD5 Diabetes Project Team.

1 reference

12 December 2020

Increase in remission rate in newly diagnosed type I diabetic subjects treated with azathioprine

1 reference

12 December 2020

Cyclosporin A treatment of young children with newly-diagnosed type 1 (insulin-dependent) diabetes mellitus. London Diabetes Study Group

1 reference

12 December 2020

Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial.

1 reference

12 December 2020

Double-blind, placebo-controlled multicenter trial using chimeric monoclonal anti-CD4 antibody, cM-T412, in rheumatoid arthritis patients receiving concomitant methotrexate

1 reference

12 December 2020

Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala).

1 reference

12 December 2020

10.1007/S11892-004-0081-X

Identifiers

DOI

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10 August 2017

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