(Q35842139)

English

A conserved aspartate residue located at the extracellular end of the binding pocket controls cation interactions in brain glutamate transporters

scientific article published on 7 October 2011

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A conserved aspartate residue located at the extracellular end of the binding pocket controls cation interactions in brain glutamate transporters (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

author name string

Noa Rosental

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Armanda Gameiro

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Christof Grewer

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Baruch I Kanner

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

7 October 2011

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

286

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

48

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

41381-41390

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Evidence for a third sodium-binding site in glutamate transporters suggests an ion/substrate coupling model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

The position of an arginine residue influences substrate affinity and K+ coupling in the human glutamate transporter, EAAT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

A conserved methionine residue controls the substrate selectivity of a neuronal glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Mechanism of cation binding to the glutamate transporter EAAC1 probed with mutation of the conserved amino acid residue Thr101.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Transport mechanism of a bacterial homologue of glutamate transporters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

The equivalent of a thallium binding residue from an archeal homolog controls cation interactions in brain glutamate transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Thallium ions can replace both sodium and potassium ions in the glutamate transporter excitatory amino acid carrier 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Transport direction determines the kinetics of substrate transport by the glutamate transporter EAAC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Aspartate-444 is essential for productive substrate interactions in a neuronal glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Cooperation of the conserved aspartate 439 and bound amino acid substrate is important for high-affinity Na+ binding to the glutamate transporter EAAC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

The glutamate-activated anion conductance in excitatory amino acid transporters is gated independently by the individual subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Individual subunits of the glutamate transporter EAAC1 homotrimer function independently of each other

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Structure of a glutamate transporter homologue from Pyrococcus horikoshii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Dynamic equilibrium between coupled and uncoupled modes of a neuronal glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Sulfhydryl modification of V449C in the glutamate transporter EAAT1 abolishes substrate transport but not the substrate-gated anion conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Glutamate translocation of the neuronal glutamate transporter EAAC1 occurs within milliseconds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Isolation of current components and partial reaction cycles in the glial glutamate transporter EAAT2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

A conserved serine-rich stretch in the glutamate transporter family forms a substrate-sensitive reentrant loop

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Two serine residues of the glutamate transporter GLT-1 are crucial for coupling the fluxes of sodium and the neurotransmitter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Stoichiometry of the glial glutamate transporter GLT-1 expressed inducibly in a Chinese hamster ovary cell line selected for low endogenous Na+-dependent glutamate uptake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Macroscopic and microscopic properties of a cloned glutamate transporter/chloride channel.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Molecular determinant of ion selectivity of a (Na+ + K+)-coupled rat brain glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Flux coupling in a neuronal glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Binding order of substrates to the (sodium + potassium ion)-coupled L-glutamic acid transporter from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

High-efficiency transformation of mammalian cells by plasmid DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Counterflow of L-glutamate in plasma membrane vesicles and reconstituted preparations from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Expression of a cloned gamma-aminobutyric acid transporter in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Cloning and expression of a rat brain L-glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Primary structure and functional characterization of a high-affinity glutamate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Active transport of L-glutamate by membrane vesicles isolated from rat brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

27 July 2018

Na(+):aspartate coupling stoichiometry in the glutamate transporter homologue Glt(Ph).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

The role of cation binding in determining substrate selectivity of glutamate transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

The substrate specificity of a neuronal glutamate transporter is determined by the nature of the coupling ion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Arginine 445 Controls the Coupling between Glutamate and Cations in the Neuronal Transporter EAAC-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Is the glutamate residue Glu-373 the proton acceptor of the excitatory amino acid carrier 1?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Distinct conformational states mediate the transport and anion channel properties of the glutamate transporter EAAT-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Coupled, but not uncoupled, fluxes in a neuronal glutamate transporter can be activated by lithium ions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Biotinylation of single cysteine mutants of the glutamate transporter GLT-1 from rat brain reveals its unusual topology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Kinetics of a human glutamate transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Ion fluxes associated with excitatory amino acid transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3308850

24 September 2018

Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.291021

21 January 2018

Arginine 447 plays a pivotal role in substrate interactions in a neuronal glutamate transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrogen ion cotransport by the renal brush border glutamate transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of three glutamate transporter subtypes in the rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation of an amino acid residue influencing potassium coupling in the glutamate transporter GLT-1 induces obligate exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity of antibodies: unexpected cross-reactivity of antibodies directed against the excitatory amino acid transporter 3 (EAAT3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple consequences of mutating two conserved beta-bridge forming residues in the translocation cycle of a neuronal glutamate transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glutamate and chloride permeation pathways are colocalized in individual neuronal glutamate transporter subunits

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rigidity of the subunit interfaces of the trimeric glutamate transporter GltT during translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate 404 is involved in the substrate discrimination of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The accessibility of a novel reentrant loop of the glutamate transporter GLT-1 is restricted by its substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/21984827

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.291021

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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