(Q35846845)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

4

1 reference

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27 January 2020

Michael D. Buschmann

7

1 reference

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27 January 2020

author name string

Mohamad Alameh

1

1 reference

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27 January 2020

Diogo Dejesus

2

1 reference

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27 January 2020

Myriam Jean

3

1 reference

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27 January 2020

Marc Thibault

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Marc Lavertu

6

1 reference

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27 January 2020

Abderrazzak Merzouki

8

1 reference

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27 January 2020

language of work or name

English

0 references

publication date

13 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Nanomedicine

27 January 2020

published in

1 reference

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27 January 2020

volume

7

1 reference

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27 January 2020

page(s)

1399-1414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 3.0 Unported

27 January 2020

copyright license

start time

1 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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11 July 2018

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11 July 2018

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Molecular-weight-dependent toxic effects of chitosans on the human keratinocyte cell line HaCaT.

11 July 2018

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11 July 2018

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11 July 2018

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Chitosan-based formulations for delivery of DNA and siRNA.

11 July 2018

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Functional gene silencing mediated by chitosan/siRNA nanocomplexes

11 July 2018

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Understanding biophysicochemical interactions at the nano-bio interface

11 July 2018

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New insights into chitosan-DNA interactions using isothermal titration microcalorimetry.

11 July 2018

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The effect of chemical modification and nanoparticle formulation on stability and biodistribution of siRNA in mice.

11 July 2018

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A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity

11 July 2018

1 reference

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Knocking down barriers: advances in siRNA delivery

11 July 2018

1 reference

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The promises and pitfalls of RNA-interference-based therapeutics

11 July 2018

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Oxidative modification of LDL: its pathological role in atherosclerosis

11 July 2018

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Anticancer activity of RecQL1 helicase siRNA in mouse xenograft models

11 July 2018

1 reference

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Chemical modification: the key to clinical application of RNA interference?

11 July 2018

1 reference

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Polycation-based nanoparticle delivery for improved RNA interference therapeutics.

11 July 2018

1 reference

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Induction of mitotic cell death in cancer cells by small interference RNA suppressing the expression of RecQL1 helicase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Interfering with disease: a progress report on siRNA-based therapeutics

11 July 2018

1 reference

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Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

RNA learns from antisense

11 July 2018

1 reference

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The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Development and characterisation of chitosan nanoparticles for siRNA delivery

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

DNA helicases required for homologous recombination and repair of damaged replication forks

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

11 July 2018

1 reference

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High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation

11 July 2018

1 reference

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Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells

11 July 2018

1 reference

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Apolipoprotein B: a clinically important apolipoprotein which assembles atherogenic lipoproteins and promotes the development of atherosclerosis

11 July 2018

1 reference

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A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

11 July 2018

1 reference

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Albumin-protamine-oligonucleotide-nanoparticles as a new antisense delivery system. Part 2: cellular uptake and effect.

11 July 2018

1 reference

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Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality

11 July 2018

1 reference

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RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

11 July 2018

1 reference

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RNA interference and the use of small interfering RNA to study gene function in mammalian systems

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

PLGA-PEI nanoparticles for gene delivery to pulmonary epithelium

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate, and cellular toxicity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

In vivo activity of nuclease-resistant siRNAs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Biodegradable nanoparticles for drug and gene delivery to cells and tissue

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Tolerance for mutations and chemical modifications in a siRNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Uptake of FITC-chitosan nanoparticles by A549 cells.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Drug-induced phospholipidosis: are there functional consequences?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Comprehensive analysis of the acute toxicities induced by systemic administration of cationic lipid:plasmid DNA complexes in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Differential regulation of human RecQ family helicases in cell transformation and cell cycle

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Gastrointestinal uptake of biodegradable microparticles: effect of particle size

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Phosphorothioate antisense oligodeoxynucleotides: questions of specificity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Delivery of DNA into mammalian cells by receptor-mediated endocytosis and gene therapy.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Passive tumor targeting of soluble macromolecules and drug conjugates

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Effective and safe gene-based delivery of GLP-1 using chitosan/plasmid-DNA therapeutic nanocomplexes in an animal model of type 2 diabetes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Enhanced gene delivery mediated by low molecular weight chitosan/DNA complexes: effect of pH and serum

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

One-step analysis of DNA/chitosan complexes by field-flow fractionation reveals particle size and free chitosan content

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Chitosan-plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

RNAi-mediated gene silencing in non-human primates.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Glycosaminoglycan destabilization of DNA-chitosan polyplexes for gene delivery depends on chitosan chain length and GAG properties

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Total RNA suitable for molecular biology analysis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

A validated 1H NMR method for the determination of the degree of deacetylation of chitosan.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

RNA interference in mammalian cells by chemically-modified RNA.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Homozygous familial defective apolipoprotein B-100. Enhanced removal of apolipoprotein E-containing VLDLs and decreased production of LDLs.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3310411

Hypersensitivity and loss of disease site targeting caused by antibody responses to PEGylated liposomes

24 September 2018

1 reference

12 December 2020

Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA

1 reference

12 December 2020

DNA protection from extracapsular nucleases, within chitosan- or poly-L-lysine-coated alginate beads

1 reference

12 December 2020

Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability

1 reference

12 December 2020

First clinical data on RNAi

1 reference

12 December 2020

Biodegradation and distribution of water-soluble chitosan in mice

1 reference

12 December 2020

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

1 reference

12 December 2020

An Update on Non-clathrin-coated Endocytosis

1 reference

12 December 2020

Identifiers

DOI

10.2147/IJN.S26571

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22457597%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

22457597

1 reference