(Q35848131)

English

Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature

scientific article published on 6 September 2005

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Endothelial targeting of a recombinant construct fusing a PECAM-1 single-chain variable antibody fragment (scFv) with prourokinase facilitates prophylactic thrombolysis in the pulmonary vasculature (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Bi-Sen Ding

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Claudia Gottstein

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Andrea Grunow

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Alice Kuo

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Kumkum Ganguly

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Steven M Albelda

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Douglas B Cines

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Vladimir R Muzykantov

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

6 September 2005

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

106

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

13

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

4191-4198

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Prevention of recurrent idiopathic venous thromboembolism

1 reference

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11 July 2018

Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy

1 reference

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11 July 2018

A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

uPAR: a versatile signalling orchestrator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Platelet-endothelial cell adhesion molecule-1-directed immunotargeting to cardiopulmonary vasculature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Generation and characterization of recombinant vascular targeting agents from hybridoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Genetic evidence for functional redundancy of Platelet/Endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Streptavidin facilitates internalization and pulmonary targeting of an anti-endothelial cell antibody (platelet-endothelial cell adhesion molecule 1): a strategy for vascular immunotargeting of drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Gene therapy to promote thromboresistance: local overexpression of tissue plasminogen activator to prevent arterial thrombosis in an in vivo rabbit model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Gene therapy for arterial thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

A tissue plasminogen activator/P-selectin fusion protein is an effective thrombolytic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Design and evaluation of a thrombin-activable plasminogen activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Towards improved thrombolytic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Construction and expression of a recombinant antibody-targeted plasminogen activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

A recombinant chimeric plasminogen activator with high affinity for fibrin has increased thrombolytic potency in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

Characterization of a chimeric plasminogen activator consisting of a single-chain Fv fragment derived from a fibrin fragment D-dimer-specific antibody and a truncated single-chain urokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

11 July 2018

P-selectin-targeting of the fibrin selective thrombolytic Desmodus rotundus salivary plasminogen activator alpha1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

A novel strategy to modify adenovirus tropism and enhance transgene delivery to activated vascular endothelial cells in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

Construction and characterization of a recombinant plasminogen activator composed of an anti-fibrin single-chain antibody and low-molecular-weight urokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

Lung Endothelium Targeting for Pulmonary Embolism Thrombolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

Medicine. Stroke--tPA and the clinic.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

The kringle stabilizes urokinase binding to the urokinase receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

Platelets inhibit the lysis of pulmonary microemboli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

Plasminogen activator inhibitor-1 is a major determinant of arterial thrombolysis resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895234

24 September 2018

Immunotargeting of catalase to the pulmonary endothelium alleviates oxidative stress and reduces acute lung transplantation injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial endocytic pathways: gates for vascular drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of plasminogen by single-chain urokinase or by two-chain urokinase--a demonstration that single-chain urokinase has a low catalytic activity (pro-urokinase)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A multicenter, randomized, placebo-controlled trial of a new form of intravenous recombinant tissue-type plasminogen activator (activase) in acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

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based on heuristic

inferred from PubMed ID database lookup

Immunoselective targeting of an anti-thrombin agent to the surface of cytokine-activated vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

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based on heuristic

inferred from PubMed ID database lookup

Superficial accumulation of plasminogen during plasma clot lysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

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based on heuristic

inferred from PubMed ID database lookup

Targeting of antibody-conjugated plasminogen activators to the pulmonary vasculature

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor Infarction in Mice by Antibody-Directed Targeting of Tissue Factor to Tumor Vasculature

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Construction and functional evaluation of a single-chain antibody fusion protein with fibrin targeting and thrombin inhibition after activation by factor Xa

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific occlusion of murine and human tumor vasculature by VCAM-1-targeted recombinant fusion proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung uptake of antibodies to endothelial antigens: key determinants of vascular immunotargeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16144802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2005-05-2002

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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