(Q35849564)

10 August 2017

Folding mechanism of the metastable serpin α1-antitrypsin (English)

1 reference

10 August 2017

Yuko Tsutsui

1

1 reference

10 August 2017

Richard Dela Cruz

series ordinal

2

1 reference

10 August 2017

Patrick L Wintrode

series ordinal

3

1 reference

10 August 2017

language of work or name

English

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publication date

5 March 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

1 reference

10 August 2017

109

1 reference

10 August 2017

12

1 reference

10 August 2017

4467-4472

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How the serpin α1-proteinase inhibitor folds

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Molecular basis of α1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Conformational pathology of the serpins: themes, variations, and therapeutic strategies

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Crystal structure of a stable dimer reveals the molecular basis of serpin polymerization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

The structural basis of serpin polymerization studied by hydrogen/deuterium exchange and mass spectrometry

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Contributions of hydrophobic domain interface interactions to the folding and stability of human gammaD-crystallin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Retarded protein folding of deficient human alpha 1-antitrypsin D256V and L41P variants

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Serpin structure, mechanism, and function

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Interactions causing the kinetic trap in serpin protein folding

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Probing the unfolding pathway of alpha1-antitrypsin.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

What do dysfunctional serpins tell us about molecular mobility and disease?

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311335

Cleaved serpin refolds into the relaxed state via a stressed conformer

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1109125109

alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1109125109

Identification of residual structure within denatured antichymotrypsin: implications for serpin folding and misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1109125109

The roles of stability and contact order in determining protein folding rates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1109125109

Pathogenic α1-Antitrypsin Polymers Are Formed by Reactive Loop-β-Sheet A Linkage

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1109125109

Alpha 1-antitrypsin Siiyama (Ser53-->Phe). Further evidence for intracellular loop-sheet polymerization

21 January 2018

1 reference

12 December 2020

Folding pathway of human alpha 1-antitrypsin: characterization of an intermediate that is active but prone to aggregation

1 reference

12 December 2020

Fluorescence-detected polymerization kinetics of human alpha 1-antitrypsin

1 reference

12 December 2020

Cooperative unfolding of a metastable serpin to a molten globule suggests a link between functional and folding energy landscapes

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1109125109

1 reference

10 August 2017

0 references

1 reference

10 August 2017

PubMed publication ID

22392975

1 reference